Experience

IBioBA - CONICET - Partner Institute of the Max Planck Society

• Argentina
• Research Services
• 1 - 100 Employee

• Principal Investigator at IBIOBA-MPSP-CONICET - Cancer stem cells and Cell plasticity

  • Mar 2012 - Present

  We study molecular and cellular mechanisms involved during the dynamic regulation of cell plasticity and how the tumor microenvironment regulates the expression of critical genes in this process. Cell plasticity, drives by stem-like tumors cells, contributes to the heterogeneous cell population observed in tumors, and consequently, their recurrence after treatment and dissemination. These cells express core transcription factors and epigenetic regulators that mediate the acquisition and maintenance of a malignant cell phenotype. Our research includes human tumor samples, mouse xenograft models, and three-dimensional (3D) cultures of cancer cells (enrichment of stem-like tumor cells) that simulate in vitro the conditions of cell plasticity in the tumor. Also, we carried out a multidisciplinary approach and advanced microscopy methods to conceive and understand the organization and dynamic progression of tumor cells in these models.



University of Buenos Aires

• Argentina
• Higher Education
• 700 & Above Employee

• Principal Investigator

  • 2009 - 2012

  Facultad de Ciencias Exactas y Naturales Departamento de Química Biológica Facultad de Ciencias Exactas y Naturales Departamento de Química Biológica



CONICET

• Argentina
• Government Administration
• 700 & Above Employee

• Postdoctoral Repatriation Fellow

  • Apr 2008 - Aug 2008



University of California, San Francisco

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Fellow

  • Mar 2005 - Dec 2007

• Postdoctoral Fellow

  • Mar 2002 - Mar 2005



Max-Planck Institute for Psychiatry

• Munich, Baviera, Alemania

• Visiting Fellow- Volkswagen Foundation Scholarship

  • 1999 - 1999