Carlos Josue Anaya
Biomedical R&D Engineer at Rockley Photonics- Claim this Profile
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Bio
Experience
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Rockley Photonics
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United Kingdom
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Medical Equipment Manufacturing
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100 - 200 Employee
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Biomedical R&D Engineer
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Mar 2022 - Present
- Designed test methods for verifying system level requirements and performed testing to verify functionality of 90% of prototypes - Compiled and consolidated engineering verification test data to review prototype design and quality - Advised quality teams on the development of a Standard Operating Procedures for meeting design controls of early clinical study prototypes, enabling testing of early prototype designs for algorithm data collection - Spearheaded development of a calibration algorithm that allowed the prototype to collect accurate temperature measurements - Developed signal processing algorithms (MATLAB & Python) for analyzing the signal-to-noise ratio of optical systems under varying temperature and power conditions
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Medtronic
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United States
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Medical Equipment Manufacturing
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700 & Above Employee
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R&D Engineer
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Feb 2020 - Present
- Led cross-functional collaborations between R&D, Quality, Regulatory, and Clinical to prepare new glucose sensor designs for testing feasibility clinical studies - Facilitated Design Reviews and created Research Development Plan and Report documents to capture the design control strategy and execution for new glucose sensor designs in early feasibility - Oversaw study enrollment and data collection for over 800 subjects in 1.5 years in 2 Medtronic Sponsored feasibility clinical studies - Managed an R&D Feasibility Study support team to coordinate subject enrollment across 14 Diabetes Clinical Center sites at an enrollment throughput of 100 subjects/month - Troubleshoot issues during study enrollment to facilitate successful insertions at the clinics and recover lost data from failed data downloads - Developed a data processing workflow and tools (Microsoft Excel, MATLAB) to reduce data collection turnaround time from 2-4 weeks, to 1-5 days, and hand-off clean data for analysis - Developed database of glucose sensor performance diagnostic data to improve identifying failure modes for new glucose sensor designs at a faster rate - Performed analytic review of study data to measure site performance and subject compliance to study protocol, and led conversations with Clinical team on areas of improvement for our clinical sites
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Neuromodulation Labratory - University of Michigan
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Ann Arbor, MI
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Graduate Student Research Assistant
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Sep 2017 - Aug 2019
- Developed electrostatic simulations of the electric fields generated by Spinal Cord Stimulation (COMSOL) and analyze their effects on neural activity in the spinal cord (NEURON+Python) - Managed supercomputer cluster allocation (SDSC Comet) to run computer simulations of electrophysiological activity in neurons (NEURON+Python, Linux OS) - Analyzed simulated signal recordings to determine that spine anatomy and electrode location affect the amplitude and shape of evoked compound action potentials - Assisted in developing and troubleshooting experimental procedures for two clinical study protocols investigating neurostimulation therapies for chronic pain - Conducted Quantitative Sensory Testing (QST) on 14 patients undergoing neurostimulation therapy for pain to identify changes in QST profile pre- and post-therapy - Led stimulation programming sessions on 10 patients undergoing neurostimulation therapy to collect stimulation thresholds and paresthesia maps for novel stimulation patterns
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Graduate Student Instructor
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Jan 2019 - Apr 2019
- Managed two teams to develop a functional alpha prototype medical device, from planning through completion - Analyzed design requirements and specifications to quickly provide technical guidance and address challenges that might arise in the design process - Resolved team conflict after facing fabrication challenges and advised development of alternative design - Reviewed and graded 69 engineering notebooks, 12 Design History Files, 12 Design Review presentations, and 2 Design Reports, in 6 days
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Undergraduate Student Research Assistant
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Mar 2015 - May 2017
- Developed an animal model (mouse) for studying diabetic neuropathic pain induced by periodic insulin treatment (insulin neuritis) to systematically investigate potential drug treatments - Maintained records of routine inspections of weight and health quality of animal subjects (mice) - Characterized changes in nerve conduction, structural nerve density in peripheral skin and cornea, and withdrawal thresholds to painful stimuli in diabetic neuropathic pain models in mice - Developed an animal model (mouse) for studying diabetic neuropathic pain induced by periodic insulin treatment (insulin neuritis) to systematically investigate potential drug treatments - Maintained records of routine inspections of weight and health quality of animal subjects (mice) - Characterized changes in nerve conduction, structural nerve density in peripheral skin and cornea, and withdrawal thresholds to painful stimuli in diabetic neuropathic pain models in mice
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Summer Research Assistant
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Jun 2016 - Jul 2016
- Assisted in evaluating designs for control circuits to operate the output of a microelectromechanical system (optoelectrode) - Developed initial design of a graphical user interface (LabVIEW) to control the light intensity, frequency, and pulse duration, of two laser diodes on an optoelectrode - Assisted in evaluating designs for control circuits to operate the output of a microelectromechanical system (optoelectrode) - Developed initial design of a graphical user interface (LabVIEW) to control the light intensity, frequency, and pulse duration, of two laser diodes on an optoelectrode
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University of California, San Diego
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La Jolla, CA
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Bioengineering Senior Design Project
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Sep 2015 - May 2016
- Developed a computer simulation (COMSOL) of an implantable, cell-based, insulin producing device to be used for the treatment of Type 1 diabetic patients - Characterized insulin producing device as a 2-dimensional finite element model of a bedsheet of insulin producing cells and investigated the mass transfer properties of oxygen at homeostatic levels - Developed a computer simulation (COMSOL) of an implantable, cell-based, insulin producing device to be used for the treatment of Type 1 diabetic patients - Characterized insulin producing device as a 2-dimensional finite element model of a bedsheet of insulin producing cells and investigated the mass transfer properties of oxygen at homeostatic levels
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Undergraduate Student Research Assistant
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Jan 2014 - Apr 2015
- Extracted bovine bone and cartilage disk samples from bovine knee tissue and drilled annuli onto disk samples - Extracted synovial fluid samples from blood donations from osteoarthritis patients in an aseptic environment - Measured Glycosaminoglycan concentrations extracted from bovine cartilage wear samples through immunohistochemistry - Extracted bovine bone and cartilage disk samples from bovine knee tissue and drilled annuli onto disk samples - Extracted synovial fluid samples from blood donations from osteoarthritis patients in an aseptic environment - Measured Glycosaminoglycan concentrations extracted from bovine cartilage wear samples through immunohistochemistry
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Education
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University of Michigan - Rackham Graduate School
Master of Science in Engineering - M.S.E., Biomedical Engineering -
University of California, San Diego - Jacobs School of Engineering
Bachelor of Science - BS, Bioengineering: Biotechnology