Experience

Industrial Technology Research Institute (ITRI)(工業技術研究院, 工研院)

• Taiwan
• Research Services
• 700 & Above Employee

• Associate Researcher

  • Nov 2018 - Present

  Hsinchu County, Taiwan, Taiwan • OmniMSC‐WH/OmniMSC‐AMI – Carried out Phase I clinical testing (on‐going) for a stem cell therapeutic promoting wound healing in diabetes and preventing inflammation acute myocardial infraction * Developed cell bank processes according to regulatory requirements: parent cell banks, master cell bank, working cell bank and cell products * Established standardized cell manufacturing processes to comply with Taiwan FDA cell therapy regulations * Evaluated cells functions by immune… Show more • OmniMSC‐WH/OmniMSC‐AMI – Carried out Phase I clinical testing (on‐going) for a stem cell therapeutic promoting wound healing in diabetes and preventing inflammation acute myocardial infraction * Developed cell bank processes according to regulatory requirements: parent cell banks, master cell bank, working cell bank and cell products * Established standardized cell manufacturing processes to comply with Taiwan FDA cell therapy regulations * Evaluated cells functions by immune modulations, angiogenesis and tissue regeneration – Assisted with technology transfer of US$199 million for OmniMSC‐AMI cell preparation to Taiwan Bio Therapeutics • Serum‐Free Melanocyte Medium – Worked as Project Manager to chemically define a serum‐free melanocyte culture technique with lower risks and with less clinical side effects • EPiTRIFull‐Thickness Skin Printing System – Refined stable, pathological 3D skin alternative models to animal models for drug screening using 3D printing technology: in‐vitro psoriasis model – Established and designed full‐thickness tissues which are cost‐effective and can be used for cosmetic and/or treatment applications – Supported the development of 3D printing system and cell printing inks for end manufacturer • Automatic Cell Production System – Automated manual operations such as medium replacement and cell passaging, resulting in 10 times the cellular density, while requiring 30‐40% less manpower – Optimized operating parameters for real‐time contamination detection functions – Developed a closed‐facility GMP manufacturing automatic cell production system • AI for Cell Identification – Created an AI algorithm for early prediction of cell harvesting viability to avoid extra passaging cycles (two cycles with AI vs. five cycles without) – Applied DNN models(ResNet‐50)to classify aged versus young cells with 93% accuracy Show less



Micromechanics Laboratory at UC Irvine

• Lab manager

  • Jun 2017 - Nov 2018

  Irvine, California



UC Irvine

• United States
• Higher Education
• 700 & Above Employee

• Graduate Student at UC Irvine

  • Sep 2016 - Jun 2018

  Irvine, California, USA • Developed a cardiomyocyte cell culture micro-fabrication for cardiotoxicity in rapid drug screening – Cultured mouse/rat cardiomyocytes from cell lines to primary cells – Manufactured cell culture micro‐fabrications using clean‐room protocols – Performed data clustering analysis on cell culture images using MATLAB/ImageJ



National Taiwan University

• Taiwan
• Higher Education
• 700 & Above Employee

• Resarch Assistant in Institute of Applied Mechanics at NTU

  • Aug 2014 - Aug 2016

  Taipei City, Taiwan •Designed new microfluidic platform for angiogenesis and tumorigenesis •Developed a smart air cushion for weight measurement of wheel chair bound patients to give correct drug dosages Research field: Biomechanical Microsystem Lab, working on microfluidic project