Calum Henderson
Senior Process Development Scientist at AB BIOTECHNOLOGY LIMITED- Claim this Profile
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Bio
Experience
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AB BIOTECHNOLOGY LIMITED
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United Kingdom
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Biotechnology Research
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1 - 100 Employee
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Senior Process Development Scientist
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Apr 2023 - Present
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Process Development Scientist
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May 2021 - Apr 2023
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Almac Group
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United Kingdom
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Pharmaceutical Manufacturing
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700 & Above Employee
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GMP peptide synthesis scientist
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Sep 2020 - May 2021
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University of Dundee
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United Kingdom
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Research Services
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700 & Above Employee
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Masters Student project
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Nov 2019 - Aug 2020
My masters project focused on the screening of the compounds synthesised over the course of my honours project and summers placement. This was achieved through screening of compounds in HEK293 cell lines before carrying out time and concentration dependency studies for most promising compounds. Hit validation was then carried out on hit compounds and the recruited E3 ligase was identified via a pulldown proteomic approach. My masters project focused on the screening of the compounds synthesised over the course of my honours project and summers placement. This was achieved through screening of compounds in HEK293 cell lines before carrying out time and concentration dependency studies for most promising compounds. Hit validation was then carried out on hit compounds and the recruited E3 ligase was identified via a pulldown proteomic approach.
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University of Dundee
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United Kingdom
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Research Services
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700 & Above Employee
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Honours Project
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Sep 2018 - Dec 2018
My honours project focused on the synthesis of two PROTAC libraries. The project utilised a number of organic synthesis techniques to carry out the parallel synthesis of a total of 36 compounds over the course of the 3-month project. This project built off my previous summer placement giving a longer period of time to plan and design my project to optimise my time.
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Student Intern
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Aug 2018 - Oct 2018
As part of a University of Dundee summer placement I joined the Ciulli group carrying out the synthesis of a library of PROTAC molecules. Through this project I carried out parallel synthesis of compounds diversifying the compounds at each stage of the synthesis to introduce diversity into the final library produced by this project to ultimately synthesise 34 compounds.
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University of Dundee
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United Kingdom
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Research Services
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700 & Above Employee
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Student Intern
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Aug 2017 - Oct 2017
As part of my first placement I joined the BCDD unit at the university of Dundee, helping to synthesis a library of compounds for screening in a future high through-put screen. Through-out the project I synthesised a number of different compounds through a number of chemical reactions including Mitsunobu, SnAr, Sulphonamides and reductive amination reactions. As part of my first placement I joined the BCDD unit at the university of Dundee, helping to synthesis a library of compounds for screening in a future high through-put screen. Through-out the project I synthesised a number of different compounds through a number of chemical reactions including Mitsunobu, SnAr, Sulphonamides and reductive amination reactions.
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Education
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University of Dundee
MSci, Biological Sciences and Drug Discovery