Bruno Manta
Senior Scientist at Institut Pasteur de Montevideo- Claim this Profile
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Bio
Experience
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Institut Pasteur de Montevideo
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Research Services
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1 - 100 Employee
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Senior Scientist
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Mar 2021 - Present
Adjunct Researcher at Microbial Genomics Lab (PI Dr. Gregorio Iraola -https://iraola-lab.com) Working on developing a new research program on enzyme discovery in microorganisms. Interested in microbial chemical ecology, diet-microbiome interaction, fermented food, enzyme technology, biochemistry. Adjunct Researcher at Microbial Genomics Lab (PI Dr. Gregorio Iraola -https://iraola-lab.com) Working on developing a new research program on enzyme discovery in microorganisms. Interested in microbial chemical ecology, diet-microbiome interaction, fermented food, enzyme technology, biochemistry.
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Universidad de la República
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Higher Education
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1 - 100 Employee
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Assistant Professor
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Feb 2021 - Present
Assistant Faculty (Prof. Adjunto Grado 3) Department of Physiopathology, School of Dentistry. Interim role as Department Head, shared with another Adj. Faculty. Teaching administration, HHRR management and administrative roles.
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Adjunct Faculty
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Apr 2020 - Feb 2021
Adjunct Faculty (non-tenured) at School of Medicine, Universidad de la República. Member of PAyS ("Programa de Alimentos y Salud Humana" - UDELAR-BID-gobierno nacional)
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PEDECIBA
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Higher Education
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1 - 100 Employee
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Faculty member (honorary) - Chemistry and Biology
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Mar 2014 - Present
Lecturer, Advisor and reviewer at National Science Postgraduate Program (Uruguay). Lecturer, Advisor and reviewer at National Science Postgraduate Program (Uruguay).
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ANII
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Uruguay
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Government Administration
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1 - 100 Employee
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National System of Researchers (SNI) - Level 1
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May 2010 - Present
Scholarship from National Research and Innovation Agency (ANII, Uruguay). Scholarship from National Research and Innovation Agency (ANII, Uruguay).
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New England Biolabs
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United States
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Biotechnology Research
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500 - 600 Employee
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Senior Postdoctoral Researcher
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Feb 2018 - Mar 2020
Focus on methionine sulfoxide reductases (Msr). I applied bacterial genetics for discovering of new redox enzymes. Genetic selections, synthetic lethal screen and chemical screen, combined with metagenomic libraries and (some) biochemistry. Focus on methionine sulfoxide reductases (Msr). I applied bacterial genetics for discovering of new redox enzymes. Genetic selections, synthetic lethal screen and chemical screen, combined with metagenomic libraries and (some) biochemistry.
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Brigham and Women's Hospital / Harvard Medical School
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United States
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Alternative Medicine
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1 - 100 Employee
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Postdoctoral Research Fellow
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Sep 2015 - Jan 2018
Focus on MICALs (methionine oxidases). I developed tools to investigate mechanism and inhibition of MICALs, key component of the only targeted, specific, reversible redox control based on methionine oxidation. Sponsored by The Pew Charitable Trust. Focus on MICALs (methionine oxidases). I developed tools to investigate mechanism and inhibition of MICALs, key component of the only targeted, specific, reversible redox control based on methionine oxidation. Sponsored by The Pew Charitable Trust.
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Postdoctoral Research Fellow
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Oct 2013 - Sep 2015
Focus on glutaredoxins (Grx) and glutathione transferases (GST/MAPEG). Identification, characterization and validation of new drug targets using biochemical and biological approaches. Funded by Institut Pasteur Postdoctoral Fellows.
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PHD Student
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Jan 2009 - Oct 2013
PhD in Marcelo Comini's Lab, working on redox biology of trypanosomal glutaredoxins
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Research Assistant
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Sep 2006 - Jan 2009
Service and support to research programs in FPLC, light scattering (DLS/MALS, SEC-MALS), differential scanning calorimetry (DSC), isothermal titration calorimetry (ITC), circular dichroism (CD), fluorescence spectroscopy (steady-state, time-resolved and anisotropy).
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Instructor
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Feb 2013 - Aug 2015
Focus on peroxiredoxins (Prx), thioredoxins (Trx), glutaredoxins (Grx) and cysteine reactivity. My work changed over the years, from hands-on positions to advisory and management roles. Focus on peroxiredoxins (Prx), thioredoxins (Trx), glutaredoxins (Grx) and cysteine reactivity. My work changed over the years, from hands-on positions to advisory and management roles.
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Università degli Studi di Padova
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Italy
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Higher Education
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700 & Above Employee
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Visiting Professor
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Jul 2014 - Nov 2014
Training in Nuclear Magnetic Resonance (NMR) spectroscopy. Funded by The Coimbra group, fellows for Young Professors. Training in Nuclear Magnetic Resonance (NMR) spectroscopy. Funded by The Coimbra group, fellows for Young Professors.
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Visiting Fellow
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Nov 2013 - Dec 2013
Training in Nuclear Magnetic Resonance (NMR) Spectroscopy. Funded by the “International Relations Office” of the University of Padova. Training in Nuclear Magnetic Resonance (NMR) Spectroscopy. Funded by the “International Relations Office” of the University of Padova.
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Heidelberg University
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Germany
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Higher Education
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700 & Above Employee
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Visiting Fellow
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Mar 2010 - Jul 2010
Training in Molecular Parasitology in Dr. R.L. Krauth-Siegel's lab, BHZ-Heidelberg University. Funded by National Agency of Research and Innovation (Uruguay). Training in Molecular Parasitology in Dr. R.L. Krauth-Siegel's lab, BHZ-Heidelberg University. Funded by National Agency of Research and Innovation (Uruguay).
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Institut Pasteur
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France
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Research Services
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700 & Above Employee
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Visiting Fellow
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Oct 2008 - Dec 2008
Training in microcalorimetry (ITC and DSC) under the direction of Drs. Francis Schaeffer and Pedro M. Alzari. Training in microcalorimetry (ITC and DSC) under the direction of Drs. Francis Schaeffer and Pedro M. Alzari.
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Teacher Assistant
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Jan 2004 - Jul 2007
Teacher Assistant in course of Biochemistry, Enzymology and Fluorescence spectroscopy. Teacher Assistant in course of Biochemistry, Enzymology and Fluorescence spectroscopy.
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Education
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Universidad de la República
Doctor of Philosophy (Ph.D.), Biochemistry -
Universidad de la República
Master’s Degree, Biochemistry -
Universidad de la República
Bachelor of Science (B.Sc.), Biochemistry