Bruno Quiroga Fisichella

Associate Scientist I -Medicinal Chemistry at FogPharma
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Boston, Massachusetts, United States, US
Languages
  • Italian Native or bilingual proficiency
  • Spanish Native or bilingual proficiency
  • English Native or bilingual proficiency
  • French Professional working proficiency

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
Join now
You need to have a working account to view this content.
Join now

Credentials

  • Genome Engineering: CRISPR Advanced Certificate Program
    CRISPR BIOTECH ENGINEERING
    Jan, 2021
    - Nov, 2024

Experience

  • FogPharma
    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Associate Scientist I -Medicinal Chemistry
      • Oct 2022 - Present

      • Design and synthesize novel stapled peptides based on biochemical SAR • Independently operate and maintain automated peptide synthesizers • Troubleshoot and optimize reaction conditions • Functionalize peptides via on-resin chemistry • Characterize products by LCMS • Design and synthesize novel stapled peptides based on biochemical SAR • Independently operate and maintain automated peptide synthesizers • Troubleshoot and optimize reaction conditions • Functionalize peptides via on-resin chemistry • Characterize products by LCMS

  • Northeastern University
    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • Jul 2021 - Jun 2023

      Manetsch Research GroupDiversification and structure-activity relationship of 4(1H)-quinolones• Perform multistep synthesis of 4(1H)-quinolones for the development and diversification of antimalarial agents• Execute manual (normal-phase) column chromatography • Characterize products by TLC, LC-MS, and 1H NMR.

    • Research Assistant
      • Jan 2021 - Sep 2021

      Advanced Drug Delivery Research (ADDRES) LaboratoryDevelopment of pharmacokinetic models for griseofulvin and celecoxib - NIH funded • Studied the mechanistic effect of co-dosed surfactants, lipids, and proteins on dynamic processes governing the oral absorption of griseofulvin and celecoxib• Conducted drug solubility, drug dissolution, lipid digestion, and proteolysis studies under simulated gastrointestinal conditions• Analyzed samples via RP-HPLC and SDS-PAGE• Managed inventory Show less

    • Research Assistant
      • May 2021 - Jul 2021

      Laboratory for Neglected Disease Drug DiscoveryStructure-activity relationship exploration of imidazo[1,2-a]pyridines • Explored reliable synthetic routes for imidazo[1,2-a]pyridine structural analogs against methicillin-resistant S. aureus• Purified products via manual (normal-phase) and automated (reverse-phase) column chromatography (Biotage), and vacuum distillation• Characterized analogs by TLC, LC-MS, and 1H NMR

  • University of Miami
    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • Jan 2018 - Sep 2019

      LeBlanc Research GroupCarbon quantum dot mediated photocatalysis. • Conducted synthesis of carbon quantum dots • Purified products via chromatography (SEC) • Characterized carbon quantum dots (FTIR, UV-vis, fluorescence) • Participated in microscopical analyses (AFM, TEM) • Conducted water-splitting reaction via solar light simulation • Performed free radical scavenging • Managed inventory Gene silencing therapy for Alzheimer’s disease. • Conducted synthesis and conjugation of carbon quantum dots • Purified adducts via dialysis and chromatography (TLC) • Perform spectroscopy studies (UV-vis, fluorescence) and gel electrophoresis • Directed siRNA-Carbon Dot coupling reactions Carbon quantum dot conjugation for drug delivery. • Conducted synthesis and conjugation of carbon quantum dots • Purified the adducts via SEC • Characterized nanoparticles (FTIR, UV-vis, fluorescence) • Participated in Confocal microscopical analyses • Performed In vivo testing with zebrafish Show less

    • Research Assistant
      • Aug 2018 - Apr 2019

      Advanced Research for the Exploration of Space (ARES) lab Generation of radiation-shielding magnetic fields on Mars- DARPA funded• Created weekly radiation dosimetry reports• Tested organic and inorganic superconductors and dopants• Prototyped toroid magnetic fields

  • Miami Dade College
    • United States
    • Higher Education
    • 700 & Above Employee
    • Peer Lead Team Learning (PLTL) Leader
      • Aug 2018 - May 2019

      Organic Chemistry Peer-Led Team Learning (PLTL) Leader • Facilitated Organic Chemistry I recitation• Created weekly assessments • Communicated with professors• Prepared students for their ACS Organic Chemistry examinations

    • Research Assistant
      • Jun 2018 - May 2019

      Department of Natural Sciences.Antimicrobial activity of Bursera simaruba.• Preparation of plant ethanolic extracts• Fractioning based on polarity and acid-base separations• Conducted phytochemical screening• Performed free radical scavenging analysis

    • Peer Academic Leader
      • May 2018 - May 2019

      Peer Academic Leader (PAL) • Tutored general biology, general chemistry, organic chemistry, physics for engineering, algebra, trigonometry, multivariable calculus, and differential equations• Communicated with professors • Hosted review sessions

Education

  • Northeastern University
    Bachelor of Science - BS, Chemical Engineering and Biochemistry
    2019 - 2022
  • Miami Dade College
    Associate of Arts - AA, Chemical Engineering
    2017 - 2019

Community

You need to have a working account to view this content. Click here to join now