Blake Breitmeyer

Senior Analytical R&D Scientist at AJNA BioSciences
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Contact Information
us****@****om
(386) 825-5501
Location
Colorado Springs, Colorado, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Analytical R&D Scientist
      • Aug 2021 - Present

      Method Development on QTOF-MS/MS coupled with HPLC for biopharmaceutical drug discovery to undergo clinical evaluation, regulatory review, and commercial drug development. AJNA BioSciences is a botanical drug development company focused on psilocybin and other naturally derived psychedelics to target innovative therapies for depression, addiction, PTSD, and Alzheimer's and Parkinson's diseases. Method Development on QTOF-MS/MS coupled with HPLC for biopharmaceutical drug discovery to undergo clinical evaluation, regulatory review, and commercial drug development. AJNA BioSciences is a botanical drug development company focused on psilocybin and other naturally derived psychedelics to target innovative therapies for depression, addiction, PTSD, and Alzheimer's and Parkinson's diseases.

  • Apex Laboratory, Physician-Owned Lab
    • Colorado Springs, Colorado Area
    • Clinical Laboratory Chemist, Laboratory Supervisor
      • Oct 2015 - Jan 2022

      -Performed urine drug toxicology analysis using LC-MS/MS. -Calibrated, maintained and operated a variety of laboratory equipment including liquid chromatography equipment, MS/MS triple quadrupole instrumentation, immunoanalyzers, analytical balances, centrifuges, pH meters, incubators, and air and positive-displacement pipettes. -Completed an LC-MS/MS method validation for a 55-analyte urine drug confirmation panel. -Manages and monitors all QA/QC aspects of the lab, including drafting, revising and updating standard operating procedures (SOPs) and conducting CAP proficiency testing. -Trained and supervised clinical laboratory staff. Show less

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Method Development Supervisor, Quality Control R&D
      • Aug 2019 - Jun 2021

      -Performs novel method development and validation for cannabinoid potency analysis following USP/ICH guidelines. -Supervises and trains a team of chemists for research and development projects involving LC-MS/MS, LC-DAD, GC-MS, and sample prep extraction. -Validates analytical sample prep and potency analysis methods for 0.0% THC broad-spectrum cannabinoid products. -Identifies and resolves analytical problems relating to chromatographic separation, detection, and instrumentation system suitability. Show less

    • United States
    • Research Services
    • 1 - 100 Employee
    • Analytical Chemist, R&D
      • Aug 2018 - Aug 2019

      -Performed stability-indicating method development and validation of active pharmaceutical ingredients using LC-MS and LC-DAD for a GMP-regulated/ISO 17025 certified research organization. -Supervised and trained chemists for forced degradation studies of active pharmaceutical ingredients. -Performed potency analysis and quality review on active pharmaceutical ingredient testing. -Identified and resolved analytical challenges relating to chromatographic separation and instrumentation system suitability. Show less

    • France
    • Biotechnology
    • 1 - 100 Employee
    • LC-MS/MS Analyst, Clinical Laboratory Services
      • Aug 2017 - Jun 2018

      -Performed sample preparation of 100+ clinical samples per day utilizing solid phase extraction (SPE) and LC-MS/MS instrumentation.-Performed chromatographic data analysis of confirmatory testing results on urine and oral fluid matrices to aid physicians in medication management and clinical diagnostics. -Supported laboratory process compliance by drafting and/or optimizing methods, SOPs, job aides and policies when necessary.-Identified and resolved analytical problems based on interpretations of QA/QC results. Show less

    • Analytical Chemist, Contract Research Organization
      • Aug 2017 - Jun 2018

      -Supported bioanalytical method validation, sample analysis, data management and report development. -Ensured all data was analyzed, processed, compiled in a timely manner and met appropropriate acceptance criteria. -Operated and ensured calibration of a variety of laboratory equipment including liquid chromatography equipment, MS/MS triple quadrupole instrumentation, UV-VIS spectrophotometers, analytical balances, centrifuges, pH meters, water purification systems, positive-pressure manifolds, incubators, and air and positive-displacement pipettes.-Reconciled technical viewpoints and ideas in the application of established standards, methods, and procedures when anomalous study situations existed.-Collaborated with chemists and customers to solve analytical requests and problems, evaluate and update SOPs, and to communicate progress and status of current projects to appropriate personnel. Show less

    • Lab Instructor II
      • Jun 2009 - May 2014

      Taught general and organic chemistry laboratory classes to students enrolled in chemistry, biology, and pre-med disciplines. Responsibilities included weekly lecture of theory behind lab procedure and reaction(s) studied, supervising procedures, monitoring lab materials and lab safety, handling and disposing of chemicals, compiling and grading exams, grading weekly lab reports.

    • Research Assistant
      • Jun 2009 - May 2014

      Various Projects:Researched in accordance with an NMR grant from the National Science Foundation to develop a guided inquiry experiment for students on C-NMR and H-NMR methods used for an Anasazi 60 MHz NMR instrument. Incorporated use of the instrument into general chemistry honors lab sections by authoring and optimizing a full laboratory experiment procedure.Performed sample analysis and processed proton and carbon spectra using NUTS 3.0.1 software.

    • United States
    • Hospitals and Health Care
    • 1 - 100 Employee
    • Clinical Research Consultant
      • Nov 2008 - Apr 2009

      Performed NMR analysis on samples of n-butyl cyanoacetate to confirm chemical structure and evaluate purity of distilled samples for application as commercial surgical adhesive. Performed NMR analysis on samples of n-butyl cyanoacetate to confirm chemical structure and evaluate purity of distilled samples for application as commercial surgical adhesive.

Education

  • University of Colorado Colorado Springs
    Bachelor's degree, Chemistry
    2003 - 2007
  • University of Colorado Colorado Springs
    Bachelor's degree, Biology
    2003 - 2007

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