Bilge Gungoren
Computational Biologist at Barrier Biosciences- Claim this Profile
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Experience
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Barrier Biosciences
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United States
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Biotechnology
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1 - 100 Employee
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Computational Biologist
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Mar 2023 - Present
Los Angeles, California, United States
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Caltech
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United States
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IT Services and IT Consulting
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1 - 100 Employee
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Undergraduate Research Assistant
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Oct 2019 - Mar 2023
Pasadena, California, United States - Synthesized gas vesicle (GV) derivatives, hollow protein structures, to implement ultrasound imaging on a cellular level. - Worked on expressing and purifying protein nanostructures bicones, smaller GV derivatives, from E. coli cultures to study their acoustic properties. - Researched potential uses of bicones as therapeutic and diagnostic agents for tumors and neurodegenerative diseases.
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Undergraduate Teaching Assistant
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Jan 2022 - Jun 2022
Pasadena, California, United States
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ArsenalBio
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Brazil
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Retail
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Computational Biology Intern
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Jun 2022 - Sep 2022
Remote - Developed interactive web applications in collaboration with various divisions to make data visualizations and analysis easy and accessible company-wide - Applied statistical tests such as ANOVA and logrank test on large datasets with flexible subsetting options to make significance analysis versatile and convenient - Packaged web applications into Docker to streamline sharing and deployment
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Washington University in St. Louis
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Research Assistant
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Aug 2021 - Jun 2022
Remote - Obtaining methylation data from cell-free DNA in the blood to deconvolve immune cells populations that have infiltrated cancerous tumors. - Contributing to a coding pipeline that obtains, analyzes, and reports methylation information from sequenced DNA. - Applying the deconvolution data to gain insight on the type of immune cells found in tumors and personalize immunotherapy to improve therapeutics and prognosis.
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Summer Undergraduate Research Fellowship
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Jun 2021 - Aug 2021
Pasadena, California, United States - Obtained methylation data from cell-free DNA in the blood to deconvolve immune cells populations that have infiltrated cancerous tumors. - Contributed to a coding pipeline that obtains, analyzes, and reports methylation information from sequenced DNA. - Used the deconvolution data to gain insight on the type of immune cells found in tumors and personalize immunotherapy to improve therapeutics and prognosis.
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Undergraduate Teaching Assistant
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Sep 2020 - Jun 2021
Pasadena, California, United States
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Summer Undergraduate Research Fellowship
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Jun 2020 - Sep 2020
Pasadena, California, United States - Researched and implemented ways to edit gas vesicle (GV) expression genes in cyanobacteria to express GV derivatives. - Designed CRISPR (clustered regularly interspaced short palindromic repeats) guides and repair templates to perform precise deletions in two GV expression genes. - Implemented a program to check for off-target matches for CRISPR guides in cyanobacteria genome to avoid mismatched editing.
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Editor of the California Tec
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Jan 2020 - Jun 2020
Pasadena, California, United States
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Robert College
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Türkiye
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Venture Capital and Private Equity Principals
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1 - 100 Employee
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President of Robert College Science and Medicine Club
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Sep 2018 - May 2019
Istanbul, Turkey
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Koç University
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Appliances, Electrical, and Electronics Manufacturing
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1 - 100 Employee
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Summer Research Program for High School Students
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Jul 2018 - Aug 2018
Istanbul, Turkey - Optimized the transformation of regular cells into iPSCs to improve the yield. - Transformed iPSCs to model RTD, a neurodegenerative disease, by using CRISPR and RNAi to knockdown and knockout genes associated with RTD. - Obtained neural cells from transformation of iPSCs to test therapeutic drugs on RTD.
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Koç Üniversitesi Hastanesi
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Türkiye
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Hospitals and Health Care
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700 & Above Employee
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Summer Research Assistant
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Jun 2017 - Jul 2017
Istanbul, Turkey - Worked on adjusting the process of baking milk-containing snacks for children to adjust the level of milk protein still remaining after the process. - Extracted and analyzed the protein content of the snacks using SDS-PAGE to determine how much milk protein left. - Used the data obtained from these snacks to make hypoallergenic milk-containing snacks for children with intolerance to milk-proteins.
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Education
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Caltech
Bachelor of Science - BS, Chemical Engineering