Bilge Gungoren

Computational Biologist at Barrier Biosciences
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Location
Pasadena, California, United States, US

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Experience

    • United States
    • Biotechnology
    • 1 - 100 Employee
    • Computational Biologist
      • Mar 2023 - Present

      Los Angeles, California, United States

    • United States
    • IT Services and IT Consulting
    • 1 - 100 Employee
    • Undergraduate Research Assistant
      • Oct 2019 - Mar 2023

      Pasadena, California, United States - Synthesized gas vesicle (GV) derivatives, hollow protein structures, to implement ultrasound imaging on a cellular level. - Worked on expressing and purifying protein nanostructures bicones, smaller GV derivatives, from E. coli cultures to study their acoustic properties. - Researched potential uses of bicones as therapeutic and diagnostic agents for tumors and neurodegenerative diseases.

    • Undergraduate Teaching Assistant
      • Jan 2022 - Jun 2022

      Pasadena, California, United States

    • Brazil
    • Retail
    • Computational Biology Intern
      • Jun 2022 - Sep 2022

      Remote - Developed interactive web applications in collaboration with various divisions to make data visualizations and analysis easy and accessible company-wide - Applied statistical tests such as ANOVA and logrank test on large datasets with flexible subsetting options to make significance analysis versatile and convenient - Packaged web applications into Docker to streamline sharing and deployment

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Aug 2021 - Jun 2022

      Remote - Obtaining methylation data from cell-free DNA in the blood to deconvolve immune cells populations that have infiltrated cancerous tumors. - Contributing to a coding pipeline that obtains, analyzes, and reports methylation information from sequenced DNA. - Applying the deconvolution data to gain insight on the type of immune cells found in tumors and personalize immunotherapy to improve therapeutics and prognosis.

    • Summer Undergraduate Research Fellowship
      • Jun 2021 - Aug 2021

      Pasadena, California, United States - Obtained methylation data from cell-free DNA in the blood to deconvolve immune cells populations that have infiltrated cancerous tumors. - Contributed to a coding pipeline that obtains, analyzes, and reports methylation information from sequenced DNA. - Used the deconvolution data to gain insight on the type of immune cells found in tumors and personalize immunotherapy to improve therapeutics and prognosis.

    • Undergraduate Teaching Assistant
      • Sep 2020 - Jun 2021

      Pasadena, California, United States

    • Summer Undergraduate Research Fellowship
      • Jun 2020 - Sep 2020

      Pasadena, California, United States - Researched and implemented ways to edit gas vesicle (GV) expression genes in cyanobacteria to express GV derivatives. - Designed CRISPR (clustered regularly interspaced short palindromic repeats) guides and repair templates to perform precise deletions in two GV expression genes. - Implemented a program to check for off-target matches for CRISPR guides in cyanobacteria genome to avoid mismatched editing.

    • Editor of the California Tec
      • Jan 2020 - Jun 2020

      Pasadena, California, United States

    • Türkiye
    • Venture Capital and Private Equity Principals
    • 1 - 100 Employee
    • President of Robert College Science and Medicine Club
      • Sep 2018 - May 2019

      Istanbul, Turkey

    • Appliances, Electrical, and Electronics Manufacturing
    • 1 - 100 Employee
    • Summer Research Program for High School Students
      • Jul 2018 - Aug 2018

      Istanbul, Turkey - Optimized the transformation of regular cells into iPSCs to improve the yield. - Transformed iPSCs to model RTD, a neurodegenerative disease, by using CRISPR and RNAi to knockdown and knockout genes associated with RTD. - Obtained neural cells from transformation of iPSCs to test therapeutic drugs on RTD.

    • Türkiye
    • Hospitals and Health Care
    • 700 & Above Employee
    • Summer Research Assistant
      • Jun 2017 - Jul 2017

      Istanbul, Turkey - Worked on adjusting the process of baking milk-containing snacks for children to adjust the level of milk protein still remaining after the process. - Extracted and analyzed the protein content of the snacks using SDS-PAGE to determine how much milk protein left. - Used the data obtained from these snacks to make hypoallergenic milk-containing snacks for children with intolerance to milk-proteins.

Education

  • Caltech
    Bachelor of Science - BS, Chemical Engineering
    2019 - 2023

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