Experience

Rheonix, Inc

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Jun 2016 - Present

  Ithaca, NY Rheonix develops fully automated and integrated molecular testing devices. Rheonix Innovation Center develops core technology.



Cornell University

• United States
• Higher Education
• 700 & Above Employee

• Senior Research Associate

  • Jul 2013 - May 2016

  Ithaca, New York Area I am currently working on three projects; 1) engineering micro-scale array of habitats for investigating environmental factors affecting cyanobacterial harmful algal blooms; 2) transport and migration behavior of Shewanella sp. for bioelectrochemical systems; and 3) 3D in vitro models for breast tumor chemoinvasion.

• Research Associate

  • Apr 2010 - Jun 2013

  I am currently working on a cancer motility and invasion study under well-defined chemical microenvironments (Physical Sciences – Oncology Center, funded by the NCI through the NIH). With a hypothesis that chemokines, utilized for immune cell trafficking, are also used by malignant breast cancers (MDA-MB-231) for their directionality, a stable gradient of the chemokines over the cell culture chamber was established, and the cell motility was analyzed. Our quantitative results reveal the… Show more I am currently working on a cancer motility and invasion study under well-defined chemical microenvironments (Physical Sciences – Oncology Center, funded by the NCI through the NIH). With a hypothesis that chemokines, utilized for immune cell trafficking, are also used by malignant breast cancers (MDA-MB-231) for their directionality, a stable gradient of the chemokines over the cell culture chamber was established, and the cell motility was analyzed. Our quantitative results reveal the importance of complex effects of multiple chemokines and growth factors within the tumor microenvironments

• Research Associate

  • Mar 2008 - Mar 2010

  I am working on the project about development of a bioprocess on a chip. I have developed a miniaturized bioreactor for animal cell cultures producing therapeutic proteins and compared cell growth, viability and target protein producion to those in conventional methods such as spinner flasks. The minibioreactor provides a superior environment, resulting in better oxygen transfer, viability, specific growth rate, and target protein production (two-fold). Other culture modes such as fed-batch and… Show more I am working on the project about development of a bioprocess on a chip. I have developed a miniaturized bioreactor for animal cell cultures producing therapeutic proteins and compared cell growth, viability and target protein producion to those in conventional methods such as spinner flasks. The minibioreactor provides a superior environment, resulting in better oxygen transfer, viability, specific growth rate, and target protein production (two-fold). Other culture modes such as fed-batch and perfusion have been studied, too. Product assessment units will be designed and integrated with the minibioreactor.

• Postdoctoral Assoicate

  • May 2004 - Feb 2008

  I have worked on the environmental effect on the cell growth and virulence factor induction with Pseudomonas syrinage pv. tomato DC3000 in hrp-inducing minimal medium. I found that iron is the growth limiting nutrient and is involved in the virulence induction with chemostat cultures. The results were recently published in the Applied and Environmental Microbiology.