Beatrice Tyrrell
Principal Medical Writer at Aspire Scientific Ltd- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
0
/5.0 / Based on 0 ratingsFilter reviews by:
Credentials
-
Certified Medical Publication Professional™
ISMPP (International Society for Medical Publication Professionals)Apr, 2022- Sep, 2024
Experience
-
Aspire Scientific Ltd
-
Pharmaceutical Manufacturing
-
1 - 100 Employee
-
Principal Medical Writer
-
Jun 2022 - Present
-
-
Senior Medical Writer
-
Nov 2020 - Jun 2022
-
-
Medical Writer
-
Jan 2019 - Oct 2020
-
-
-
University of Oxford
-
United Kingdom
-
Research Services
-
700 & Above Employee
-
PhD Student
-
Oct 2015 - Jan 2019
Investigating the therapeutic potential of iminosugar compounds against diverse viruses and as immunomodulators.Techniques: Containment Level 3 laboratory work with dengue virus, virological assays with dengue virus, Zika virus and Hazara virus, cytokine assays, tissue culture, qRT-PCRSupervisor: Professor Nicole Zitzmann (Director of the Oxford Glycobiology Institute and Associate Head of Department: Infection and Disease Processes, Department of Biochemistry) Investigating the therapeutic potential of iminosugar compounds against diverse viruses and as immunomodulators.Techniques: Containment Level 3 laboratory work with dengue virus, virological assays with dengue virus, Zika virus and Hazara virus, cytokine assays, tissue culture, qRT-PCRSupervisor: Professor Nicole Zitzmann (Director of the Oxford Glycobiology Institute and Associate Head of Department: Infection and Disease Processes, Department of Biochemistry)
-
-
-
Nuffield Department of Medicine
-
United Kingdom
-
Research Services
-
1 - 100 Employee
-
PhD Rotation Student
-
May 2015 - Aug 2015
Research project investigating the interaction between TRIM22 and HIV-2 infection. Techniques: tissue culture, shRNA knockdown, qPCR, flow cytometrySupervisors: Shmona Simpson (DPhil Student), Professor Sarah Rowland Jones (Principal Investigator) Research project investigating the interaction between TRIM22 and HIV-2 infection. Techniques: tissue culture, shRNA knockdown, qPCR, flow cytometrySupervisors: Shmona Simpson (DPhil Student), Professor Sarah Rowland Jones (Principal Investigator)
-
-
-
Kennedy Institute of Rheumatology
-
United Kingdom
-
Research Services
-
1 - 100 Employee
-
PhD Rotation Student
-
Mar 2015 - May 2015
Research project investigating the effects of short chain fatty acids on macrophage differentiation, in terms of epigenetic effects and implications for macrophage function. Techniques: tissue culture, Western blot, ELISA, qPCRSupervisors: Dr Julie Schulthess (Postdoctoral Scientist), Professor Fiona Powrie FRS (Director of the Kennedy Institute of Rheumatology and Principal Investigator) Research project investigating the effects of short chain fatty acids on macrophage differentiation, in terms of epigenetic effects and implications for macrophage function. Techniques: tissue culture, Western blot, ELISA, qPCRSupervisors: Dr Julie Schulthess (Postdoctoral Scientist), Professor Fiona Powrie FRS (Director of the Kennedy Institute of Rheumatology and Principal Investigator)
-
-
-
-
PhD Rotation Student
-
Oct 2014 - Feb 2015
Research project investigating the effects of iminosugar drug treatment on dengue virus infection, and the host response to infection, in human monocyte-derived macrophages.Techniques: Containment Level 3 laboratory work with dengue virus, tissue culture, ELISA, qRT-PCR, functional cytokine assay developmentSupervisors: Andrew Sayce (DPhil Biochemistry student), Dr Jo Miller (Senior Postdoctoral Scientist), Professor Nicole Zitzmann (Head of the Antiviral Research Unit and Deputy Director of the Oxford Glycobiology Institute)
-
-
-
-
Part II Student
-
Sep 2013 - Apr 2014
Research project investigating the activation of endoplasmic reticulum stress pathways - particularly the transcription of the XBP1 protein - in the response of human primary dendritic cells to infection with the intracellular pathogen Chlamydia trachomatis.Techniques: tissue culture, shRNA knockdowns, real-time qPCR and RT-PCR Supervisors: Dr Steven Webster (Research Associate), Dr Jane Goodall (Senior Research Fellow)This project was an assessed component of the BA (Hons) Natural Sciences, receiving a high First class mark.
-
-
-
Université de Lausanne - UNIL
-
Switzerland
-
Higher Education
-
1 - 100 Employee
-
Visiting Scholar
-
Jul 2013 - Aug 2013
Scholarship to the Summer Undergraduate Research Programme at the University of Lausanne, involving an 8-week individual research project in the Calandra & Roger Innate Immunity and Sepsis Laboratory, Department of Infectious Diseases, CHUV, and presentation at a poster symposium. My research was into the modulation of sirtuin expression, a class of NAD+-dependent histone deacetylase enzymes, in response to stimulation with microbial products, heat-killed microorganisms, cytokines and Danger Associated Molecular Patterns (DAMPs). Experiments were conducted using murine bone marrow-derived macrophages (BMDMs).Techniques: tissue culture, real-time quantitative PCR, Western blotting.Supervisors: Eleanora Ciarlo (PhD student), Dr Thierry Roger (Senior Lecturer)
-
-
Education
-
University of Oxford
Doctor of Philosophy (D.Phil.), Infection, Immunology and Translational Medicine -
University of Cambridge
BA Hons. (Cantab.), Natural Sciences -
King Edward VI School, Southampton
A-Levels, Biology, Chemistry, Mathematics