Experience

Orbillion Bio (YC W21)

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist - Cell line development and tissue engineering

  • Oct 2022 - Present

  San Francisco Bay Area, California, United States • Patented an innovative concept in 3D-based cell culture. • Developed animal tissue-derived cell lines (Primary satellite and adipocyte cells) - Carried out muscle cell organoid formation in suspension culture to establish a scalable system. - Worked on the proliferation and differentiation media formulation for muscle cells and improved the percentage of cell differentiation and tube formation. • Worked with various collaborator companies across the world to evaluate their… Show more • Patented an innovative concept in 3D-based cell culture. • Developed animal tissue-derived cell lines (Primary satellite and adipocyte cells) - Carried out muscle cell organoid formation in suspension culture to establish a scalable system. - Worked on the proliferation and differentiation media formulation for muscle cells and improved the percentage of cell differentiation and tube formation. • Worked with various collaborator companies across the world to evaluate their microcarrier products as a solution for scaling up cell production. • Worked closely with the bioprocessing group and evaluated media formulations, cell metabolic activities, and microparticles for muscle cell expansion in microcarrier-based spinners, and shaker suspension culture platforms. • Led the project on the fabrication of the dissolvable microcarriers and evaluated their efficacy in suspension culture which simplified the cell harvesting process. • Introduced and led the production of the cultivated meat patty burger from an edible scaffold (cultured with cells) at Orbillion.

• Scientist- Cell line development and tissue engineering

  • May 2021 - Oct 2022

  Los Angeles, California, United States



UCLA

• United States
• Higher Education
• 700 & Above Employee

• Visiting Graduate Researcher

  • Jan 2020 - May 2021

  Los Angeles, California, United States • Significantly improved soft tissue regeneration and vascularization in vivo through developing a new porous bioink for 3D bioprinting the tissue structures. Supervisors: Dr.Ali Tamayol and Dr.Nasim Annabi



University of Nebraska-Lincoln

• United States
• Higher Education
• 700 & Above Employee

• Graduate Research Assistant

  • Jan 2018 - May 2021

  Lincoln, Nebraska • Improved muscle regeneration and vascularization through in vivo printing of growth factor-loaded nanoengineered material in volumetric muscle loss animal models (VML). - Improved in vitro differentiation of myoblasts to myotubes by aligning cells through 3D bioprinting technique. - Enhanced HUVECs functionality by controlling the release of growth factors (VEGF) from loaded nanoparticles (Laponites) to improve vascularization in VML injuries. - Improved the skeletal muscle… Show more • Improved muscle regeneration and vascularization through in vivo printing of growth factor-loaded nanoengineered material in volumetric muscle loss animal models (VML). - Improved in vitro differentiation of myoblasts to myotubes by aligning cells through 3D bioprinting technique. - Enhanced HUVECs functionality by controlling the release of growth factors (VEGF) from loaded nanoparticles (Laponites) to improve vascularization in VML injuries. - Improved the skeletal muscle regeneration in volumetric muscle loss mouse animal models using in vivo printing of loaded nanoengineered hydrogel (a collaboration work with Brigham hospital, Boston). - Contributed to the development of a handheld 3D printer for in vivo printing of soft materials. • Bone tissue regeneration by developed a new approach for in situ printing of micro-engineered osteoconductive hard material. - Introduced an in situ printable osteoconductive PCL-based biomaterials and evaluated it's in vivo body reaction. - Enhanced the differentiation of hMSC to osteoblasts using an osteoconductive material (HAp). • Evaluated the effect of nanoelectrospined liquid crystal fibers scaffold on improving the differentiation of the skeletal muscle cell. Supervisor: Dr.Ali Tamayol Show less



Royan Institute

• Iran
• Biotechnology
• 300 - 400 Employee

• Graduate Research Assistant

  • 2013 - 2016

  Tehran, Iran • Developed a highly tough and self-healable dual physically crosslinked sulfated alginate-based polyurethane elastomers for vascular tissue engineering. - Synthesised and characterized the physical and mechanical properties of the polymer. - Analysed the anticoagulation activities of the polymer to prevent blood clotting and platelet adhesion to the scaffold. - Isolated HUVEC cells from the umbilical cord and evaluate the improvement of the cultured cells on the polymer. - In vivo… Show more • Developed a highly tough and self-healable dual physically crosslinked sulfated alginate-based polyurethane elastomers for vascular tissue engineering. - Synthesised and characterized the physical and mechanical properties of the polymer. - Analysed the anticoagulation activities of the polymer to prevent blood clotting and platelet adhesion to the scaffold. - Isolated HUVEC cells from the umbilical cord and evaluate the improvement of the cultured cells on the polymer. - In vivo evaluation of body reaction to the synthesized polymer. Supervisors: Professor Hossein Baharvand and Dr.Sara Rajabi Show less