Experience

Novavax

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Scientist II, Vaccine Development

  • Apr 2022 - Present

  Independent, skilled, highly motivated, enthusiastic and passionate protein structural biology lead at Novavax Inc using cryoEM as a tool for next generation vaccine development. Skilled with cryoEM infrastrucre set-up, data management and processing.Great experience with protein biochemical as well as biophysical characterization using wide range of methods-ITC, SPR, BLI, DSC, DLS, NSEM, Fluorescence polarizations, FRET etc.

• Scientist I, Discovery

  • Nov 2020 - May 2022

  Understanding and uncovering the protein based vaccine strategies



IBBR Institute for Bioscience and Biotechnology Research

• United States
• Biotechnology Research
• 1 - 100 Employee

• Scientific Researcher

  • Feb 2019 - Nov 2020

  Determining the atomic and molecular architecture of membrane protein complexes responsible for biological transport, disease, and virus assembly. I use single particle cry-electron microscopy (cryo-EM) of large, multi-subunit assemblies and X-ray crystallography to gain high-resolution insights into the molecular basis of trans-membrane communication and protein-protein interactions. Determining the atomic and molecular architecture of membrane protein complexes responsible for biological transport, disease, and virus assembly. I use single particle cry-electron microscopy (cryo-EM) of large, multi-subunit assemblies and X-ray crystallography to gain high-resolution insights into the molecular basis of trans-membrane communication and protein-protein interactions.



Dulbecco Telethon Instiute

• Genoa Area, Italy

• Senior Postdoctoral Fellow

  • Aug 2015 - Feb 2019

  Ion channels and transporters play a critical role in maintaining the normal physiology of cell for many pathophysiologic states. My research examines the molecular basis of the cellular signalling as mediated by the family of transmembrane receptors in human genome, the anion exchanger CLC-chloride ion channel proteins. We utilize a broad range of methods in biophysics, biochemistry, molecular and cell biology to understand the molecular function and atomic structures of these channels. We aim to utilize these insights towards the development of therapeutics with unique properties and novel in vivo biology.



All India Institute of Medical Sciences

• India
• Hospitals and Health Care
• 700 & Above Employee

• Research Associate

  • 2014 - Sep 2015

  Project 1: Screening of small molecules inhibiting amyloid beta fibrils critical for Alzheimer’s. Used proteomics, Biacore SPR and Fluorescence assays to investigate the small molecule interaction with Amyloid beta monomer or oligomer. Project 2: Used X-ray crystellography to understand the molecular interactions of antibiotic (e.g. Gentamicin) to investigate its side effects on human health. Project 1: Screening of small molecules inhibiting amyloid beta fibrils critical for Alzheimer’s. Used proteomics, Biacore SPR and Fluorescence assays to investigate the small molecule interaction with Amyloid beta monomer or oligomer. Project 2: Used X-ray crystellography to understand the molecular interactions of antibiotic (e.g. Gentamicin) to investigate its side effects on human health.



The University of Queensland

• Higher Education
• 700 & Above Employee

• Post Doc

  • Jan 2013 - Dec 2013

  Membrane Protein Crystallography

• Researcher PHD Student

  • Aug 2009 - Dec 2012

  PhD degree in protein Biochemistry and Biophysics. Closely worked on expressing individual or multi-protein co-complexes involving in vesicle fusion. Used various tools (Like Recombinant Protein expression, X-ray crystelography of soluble or membrane proteins (using LCP), ITC or spectroscopy to investigate protein-protein interactions) to characterize the function and atomic structures of various proteins.