Asha Wadhavaniya

Research Associate at Sardona Therapeutics
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Contact Information
us****@****om
(386) 825-5501
Location
San Francisco, California, United States, US
Languages
  • English Full professional proficiency
  • Hindi Native or bilingual proficiency
  • Gujarati Native or bilingual proficiency

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Credentials

  • Think Like a Lawyer to Make Decisions and Solve Problems
    LinkedIn
    Aug, 2021
    - Oct, 2024

Experience

  • Sardona Therapeutics
    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Associate
      • Feb 2022 - Present

      •Performing discovery, development, and implementation of multiple biochemical and metabolic assays for SAR, started with a Seed-Stage company, as a cross-functional molecular biologist and characterize the dose-dependent inhibition response of RNA binding molecules in triple-negative breast cancer cell lines and lung cancer. •Developed various biochemical and cell-based assays for lead discovery and optimization as part of the discovery biology group to determine the metabolic fate of potential drug candidates. •Supported target identification and pre-clinical drug development for in-house as well as inter-company partner compounds. •Experience with various cell growth and viability assays, establishing IC50s of drug candidates, optimization, and analysis methods. •Responsible for processing, and analysis of patient matched PBMC’s and tumor samples for translational efforts including target analysis and biomarker strategy determination. •Handled independent projects to analyze in-house compounds to establish potency on various Breast cancer and NSCLC, CRC lines. •Executed FACS immune profiling of pre-clinical samples, able to design panels, run on a flow cytometer, and analyze in FlowJo. •Planned and executed GLP and cGMP-like lab processes and supported good documentation practices. Show less

  • Georgia State University
    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Research Assistant
      • Feb 2021 - Feb 2022

      •Regulation of Androgen Receptor (AR)-Cyclin D1 axis in Quadruple Negative Breast Cancer•Understanding the role of Androgen receptor in transcriptionally regulating CyclinD1-CDK4/6 axis in Quadruple Negative Breast Cancer.•Investigating CyclinD1-CDK4/6 as a promising therapeutic target for QNBCs.•Wnt/b-catenin inhibitor(s) as a therapeutic option for Quadruple Negative Breast Cancer (QNBC)•Molecular characterization of a novel anaerobic aromatic-degrading bacterial strain BFN5•Mutagenesis of Geobacter Daltonii strain FRC-32 genes to characterize anerobic aromatic degrading genes.•Bioinformatics analysis of anaerobic biodegradation of crude oil and plastics. Show less

    • Graduate Teaching Assistant
      • Jan 2020 - Jun 2021

      Worked as Graduate Teaching Assistant for Biology and Genetics Classes, Biology Department,GSU

Education

  • Georgia State University
    Master of Science - MS, Biology, General
    2020 - 2021
  • Atlanta Technical College
    Certificate Course, Bioscience Environmental Laboratory Technologist – Technical Certificate Program
    2018 - 2019
  • Atlanta Technical College
    Certificate Course, Bioscience regulatory assurance technologist – Technical Certificate Program
    2018 - 2019
  • Houston Community College
    Associate of Science - AS, Biology/Biological Sciences, General
    2015 - 2017
  • Aurora Degree College
    Bachelor of Science - BS, Biotechnology
    2012 - 2015

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