Aoife Thornton PhD
Scientist at VICO Therapeutics B.V.- Claim this Profile
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Bio
Experience
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VICO Therapeutics B.V.
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Netherlands
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Biotechnology Research
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1 - 100 Employee
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Scientist
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Apr 2022 - Present
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Trinity College Dublin
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Ireland
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Higher Education
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700 & Above Employee
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Postdoctoral Researcher
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Oct 2020 - Feb 2022
Project manager for multidisciplinary project funded by the LouLou Foundation which investigates plasma microtubule proteins as potential biomarkers and novel therapeutic targets in CDKL5 Deficiency Disorder (CDD). The project includes clinical and preclinical work and adopts a translational approach. Project manager for multidisciplinary project funded by the LouLou Foundation which investigates plasma microtubule proteins as potential biomarkers and novel therapeutic targets in CDKL5 Deficiency Disorder (CDD). The project includes clinical and preclinical work and adopts a translational approach.
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University of Galway
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Ireland
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Higher Education
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700 & Above Employee
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PhD Researcher
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Sep 2016 - Sep 2020
Awarded NUI Galway Hardiman Scholarship to undertake a 4 year PhD in preclinical neuroscience.Project title: Examine the role of the endocannabinoid system in neuronal alterations and behavioural symptoms associated with autism.This project involved both in vitro and in vivo components allowing me to utilise a wide range of techniques such as cell culture, small animal handling and welfare, behavioural testing, drug delivery, RNA isolation, qRT-PCR, western blot, SDS-PAGE, HPLC, mass spectrometry, ELISA, immunohistochemistry.My day-to-day tasks include designing and executing experiments, analysing and interpreting data, reviewing literature, writing detailed scientific reports and abstracts for scientific meetings, presenting data at conferences and research days, attending weekly lab meetings to discuss ongoing research, collaborating on several projects in a team-based environment, demonstrating at undergraduate labs and mentoring undergraduate and postgraduate students during their research projects.I developed key interpersonal skills including project and time management, teamwork, organisational, communication and presentation skills.
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Lab demonstrator
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Sep 2016 - Dec 2019
I demonstrated at Physiology labs to undergraduate science and medicine students and at introduction to science communication (computer) labs to first year biomedical science students.Duties include: supervision of class, active participation in lab, correction of lab reports and assignments.
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University of Roehampton
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United Kingdom
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Higher Education
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700 & Above Employee
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Visiting Researcher
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May 2017 - Jul 2017
As part of my PhD program I spent two 10-week periods on a research placement in the University of Roehampton to investigate the effect of valproic acid on the proliferation of neural stem cells and the role of IL1β. I was trained and became competent in cell culture and developed the cell lines back in NUIG when the placement finished. As part of my PhD program I spent two 10-week periods on a research placement in the University of Roehampton to investigate the effect of valproic acid on the proliferation of neural stem cells and the role of IL1β. I was trained and became competent in cell culture and developed the cell lines back in NUIG when the placement finished.
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University of Galway
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Ireland
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Higher Education
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700 & Above Employee
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Final Year Undergraduate Research Project
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Sep 2015 - Dec 2015
My final year thesis examined the neurochemical mechanisms underlying impaired expression of fear-conditioned analgesia in a genotype associated with negative affect. My final year thesis examined the neurochemical mechanisms underlying impaired expression of fear-conditioned analgesia in a genotype associated with negative affect.
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Health Research Board (HRB)
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Ireland
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Research Services
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1 - 100 Employee
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Research Intern
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Jun 2015 - Aug 2015
Awarded scholarship from the HRB to partake in a summer research project. Project title: An investigation of changes in central tryptophan hydroxylase following olfactory bulbectomy in the rat. Awarded scholarship from the HRB to partake in a summer research project. Project title: An investigation of changes in central tryptophan hydroxylase following olfactory bulbectomy in the rat.
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Education
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National University of Ireland, Galway
Doctor of Philosophy - PhD, Neuroscience -
Institute of Project Management
IPMA Certified Diploma - Project Management, 1.1 -
National University of Ireland, Galway
Biomedical Science, Pharmacology -
The Hong Kong University of Science and Technology
Biomedical Science, 1.1 -
St. Vincents Secondary School Dundalk
Leaving Certificate