Experience

Institute of Molecular Biology (IMB)

• Germany
• Research
• 100 - 200 Employee

• Bioinformatician

  • Jan 2014 - Present

  • Member of the Bioinformatics Core Facility • analysis of NGS data (RNAseq, ChIPseq, iCLIP, RIPseq) • splicing analysis • teaching (analysis of ChIPseq data, analysis of iCLIP data) • Member of the Bioinformatics Core Facility • analysis of NGS data (RNAseq, ChIPseq, iCLIP, RIPseq) • splicing analysis • teaching (analysis of ChIPseq data, analysis of iCLIP data)



UC Irvine

• United States
• Higher Education
• 700 & Above Employee

• Associate Specialist

  • Apr 2012 - Dec 2013

  • Development of a pipeline for the analysis of next-generation sequencing (NGS) data combining my own Perl and R scripts with established tools like Tophat, SAMtools, and edgeR to find differentially expressed genes and exons changing splicing behavior between samples• Creation of a machine learning based classifier (a 'splicing code') to combine factors of exon recognition in order to predict splicing behavior of exons and extract common characteristics among certain exon classes• Development of bioinformatics tools and pipelines to facilitate analyses of biological experiments carried out in the lab• Training of lab scientist on bioinformatics tools and a HPC cluster to empower them to do their own analysis Show less

• Postdoc

  • Jun 2010 - Mar 2012

  • Creation of a machine learning based classifier (a 'splicing code') to combine factors of exon recognition in order to predict splicing behavior of exons and extract common characteristics among certain exon classes• Design and creation of an online database of human exon splicing events allowing easy filtering for certain exon types



Leipzig University

• Germany
• Higher Education
• 700 & Above Employee

• Postdoc

  • Apr 2009 - May 2010

  • Detection of similar and possibly duplicated human exons to find common duplication mechanisms during evolution • Identification of new microRNAs in seven worm genomes • Identification of human microRNAs, which switch off synthetic lethal partners of a gene • Detection of similar and possibly duplicated human exons to find common duplication mechanisms during evolution • Identification of new microRNAs in seven worm genomes • Identification of human microRNAs, which switch off synthetic lethal partners of a gene



University of Freiburg

• Germany
• Research
• 300 - 400 Employee

• Research Associate

  • Jun 2008 - Mar 2009

  • Development and implementation of a new approach to predict RNA-RNA interactions (IntaRNA) to find targets of small RNAs • Analysis and evaluation of factors necessary for microRNA-mRNA interactions using machine learning to provide suggestions of how to artificially design microRNAs that can function as drugs • Development and implementation of a new approach to predict RNA-RNA interactions (IntaRNA) to find targets of small RNAs • Analysis and evaluation of factors necessary for microRNA-mRNA interactions using machine learning to provide suggestions of how to artificially design microRNAs that can function as drugs