Experience

Hong Kong Center for Neurodegenerative Diseases Limited

• Research Assistant

  • Jan 2021 - Present

  I'm currently under supervision as part of the Human brain histology team in Prof. Nancy Ip's laboratory at HKUST, under Programme 1 in HKCeND. With the use of immunostaining of molecular markers on human brain AD and healthy control tissue samples from various brain banks, spatial relationships and pattern differences in plaque-associated glial interactions are studied at the microscopic level in (multiplex) widefield images and confocal stacks. I have been designing and scripting algorithm-based workflows as part of our customized 2D (ImageJ, QuPath) and 3D (Imaris, AIVIA) bioimage analysis, looking into phenotypical features of nearest-neighbor objects that are subject to compositional heterogeneity within notable patterns of spatial organization. Analysis pipelines have been developed for (semi-)automatic quantification of sampled image datasets, using both parameter-based criteria and Machine Learning-based classifiers for image processing and data taming, based on the combinations of stained markers highlighting different microanatomical features. Hypothesis-driven analysis are tailor-designed to extract relevant biological information based on relevant pattern observations. Show less



Singapore-ETH Centre

• Singapore
• Research Services
• 1 - 100 Employee

• Junior Research Assistant at ETH FCL Cognition

  • Jan 2020 - Dec 2020

  Worked as Researcher under the Future Cities Laboratory module - Cognition, Perception, and Behaviour in Urban Environments. - Recruitment and scheduling of participants - Conduct VR/desktop behavioural testing and wayfinding experiments - Pre-processing and analysis of behavioural and qualitative data - Assist with the experimental design, literature review, also write-up of progress/ final reports and manuscripts. Projects: (1) User-centred behavioural evaluation of Dynamic Guidance System design concepts in transit hub, for dynamic wayfinding (2) Appraisals and Preferences of design variations for boundary/edge conditions of pedestrian walkways Show less



Queen Mary Hospital

• Hong Kong
• Hospitals and Health Care
• 100 - 200 Employee

• Temporary Executive Assistant II

  • Sep 2019 - Dec 2019

  Provided administrative and executive support to the services of Central Nursing department - clerical duties e.g. report compilation, prepare meeting agenda, minutes and presentation materials - documentation and records keeping - Handle enquiries Provided administrative and executive support to the services of Central Nursing department - clerical duties e.g. report compilation, prepare meeting agenda, minutes and presentation materials - documentation and records keeping - Handle enquiries



Sleep and Brain Research Unit, Neurodegeneration Network at UEA

• Project Student

  • Oct 2018 - Jun 2019

  Final Year Research Project: Age-related differences in Habitual Sleep, spatial memory and navigational abilities in healthy APOE ε4 carriers Reference publication: 1. Coughlan, G., Zhukovsky, P., Puthusseryppady, V., Gillings, R., Minihane, A., Cameron, D. and Hornberger, M., 2020. Functional connectivity between the entorhinal and posterior cingulate cortices underpins navigation discrepancies in at-risk Alzheimer's disease. Neurobiology of Aging, 90, pp.110-118. 2. Tu, S., Wong, S., Hodges, J., Irish, M., Piguet, O. and Hornberger, M., 2015. Lost in spatial translation – A novel tool to objectively assess spatial disorientation in Alzheimer's disease and frontotemporal dementia. Cortex, 67, pp.83-94. Show less



STEMNET

• E-Learning Providers

• STEM Ambassador

  • Nov 2016 - Jun 2019

  A keen interest in science communication, especially in translating basic science into engaging activities with layman's terms, through STEM workshops and science weeks at primary schools. A keen interest in science communication, especially in translating basic science into engaging activities with layman's terms, through STEM workshops and science weeks at primary schools.



Amgen

• United States
• Biotechnology Research
• 700 & Above Employee

• Amgen Scholar 2018

  • Jun 2018 - Sep 2018

  Former Amgen Scholar at LMU München, as part of the Amgen Scholars European Programme 2018. I undertook an independent research project under supervision in Prof. Dr. Anton Sirota's lab, to work on technical, computational and behavioural adaptations for the use of ratCAVE - Virtual Reality (VR) system with mice, and further examining its contextual simulations for behavioural tasks. This research project was presented at poster symposiums in Graduate school of Systemic Neuroscience (GSN) Munich and at Cambridge. For reference: https://github.com/ratcave/ratcave https://ratcave.readthedocs.io/en/latest/introduction.html Reference publication : 1. Del Grosso, N., Graboski, J., Chen, W., Blanco-Hernández, E. and Sirota, A., 2017. Virtual Reality system for freely-moving rodents. bioRxiv. 2. Del Grosso, N. and Sirota, A., 2019. Ratcave: A 3D graphics python package for cognitive psychology experiments. Behavior Research Methods, 51(5), pp.2085-2093. Show less



KAIST

• Machinery Manufacturing

• Intern Researcher

  • Sep 2017 - Jun 2018

  Worked as an intern in the Hippocampus team of the System Neuroscience laboratory(SNL), under the Center of Synaptic Brain Dysfunctions (CSBD) in the Institute of Basic Science (IBS), within KAIST. Have strived to help with three research projects, assisted in the experimental work and data analysis. • Regionally-specific chemogenetic inhibition of value signals by DREADD-Gi system • Sleep and awake immobility SWRs electrophysiological recording in CA1 neurons • Value-dependent action selection under probabilistic reward delivery in T-maze variants • Data visualization of rat’s behavioural trajectories and pre-processing of spike clusters using MATlab x MClust • (Immuno-)histochemical staining and imaging of rodent brain sections Supervised by a researcher who focuses on investigating the role of CA1 in Incremental value processing during Hippocampal replays, further exploring this mechanism in rat CA3, using 24-tetrodes electrophysiological recordings. Reference publication : Jeong, Y., Huh, N., Lee, J., Yun, I., Lee, J., Lee, I. and Jung, M. (2018). Role of the hippocampal CA1 region in incremental value learning. Scientific Reports, 8(1). Show less



Graduate School of Systemic Neurosciences - LMU Munich

• Germany
• Higher Education
• 1 - 100 Employee

• Munich Brain Course Award 2018 awardee

  • Mar 2018 - Mar 2018

  Sponsored by scholarship awared by GSN-LMU Munich, to attend a course on neuroanatomical topics, at the Institute of Anatomy in Ludwig-Maximilians-Universität München. Sponsored by scholarship awared by GSN-LMU Munich, to attend a course on neuroanatomical topics, at the Institute of Anatomy in Ludwig-Maximilians-Universität München.



Harrow International Schools

• United Kingdom
• Consumer Services
• 1 - 100 Employee

• Summer Intern

  • Jul 2017 - Aug 2017

  Summer internship at the Admission Department and library of the Harrow International School Hong Kong. Summer internship at the Admission Department and library of the Harrow International School Hong Kong.



University of East Anglia

• United Kingdom
• Higher Education
• 700 & Above Employee

• Student Ambassador

  • Apr 2016 - Jul 2017

  This has provided an opportunity to support young prospective and current students in UEA, through guiding campus tours and orientation events, as well as outreach work to Secondary school and Sixth form colleges, which have built up my interpersonal relationship with colleagues, confidence in public speaking and proactive attitude towards work.

• Dean of Students(DOS) Representative

  • Mar 2016 - Jul 2017

  As a student Ambassador representing the DOS office, it was my responsibility to present fruitful university life whilst time in UEA to potential and new students, which involved giving campus tours, working at the orientation desk, assisting orientation events and generally answering questions surround university life.



Big C Cancer Charity

• United Kingdom
• Hospitals and Health Care
• 1 - 100 Employee

• Student Helper

  • Nov 2016 - Jun 2017

  Work weekly to assist the paper work in the Head office, facilitate the operation of fundraising department of the Big C Cancer Charity. Work weekly to assist the paper work in the Head office, facilitate the operation of fundraising department of the Big C Cancer Charity.

• QMH Student Attachment Programme (SVAP) 2016

  • Aug 2016 - Sep 2016

  • Served the out-patient pharmacy by dispensing appropriate medications • Observe the daily operation and shadowed clinicians in Neurology ward e.g. bedside rounds Explored the work at several Clinical Departments: - the Adult ICU - Paediatric ICU - Hematology laboratory - Department of Clinical oncology - Out-patient and In-patient pharmacy Observed in person: - Medication Reconciliation - production of Infliximab and Cytotoxic drugs in the laboratory of the Department of Clinical oncology. - Clinical trial of Fibroscan on assessing Fibrosis and Streatosis after Liver transplant Show less


Imperial College London
• Research Services
• 700 & Above Employee
• Revolutions in Biomedicine programme

  • Jun 2016 - Jul 2016


South Island School (SIS), Hong Kong

• Library Assistant

  • Aug 2015 - Aug 2015

  Worked at the Learning Resource Centre at an international school. Worked at the Learning Resource Centre at an international school.


The University of British Columbia
• Canada
• Higher Education
• 700 & Above Employee
• Summer Scholars Programme

  • Jul 2014 - Aug 2014