André Silva
Research Associate at REQUIMTE- Department of Chemistry- Claim this Profile
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English Full professional proficiency
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Portuguese Native or bilingual proficiency
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Bio
Experience
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REQUIMTE
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Portugal
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Research Services
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1 - 100 Employee
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Research Associate
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Jun 2013 - Present
My main research interest is the development of new analytical biochemistry methods for disease prognosis thought the identification of biomarkers. Current research focuses in developing quantification methods and understanding the role of toxic iron species in the pathology of diseases such as hereditary hemochromatosis (HH) and diabetes mellitus (DM). Two research lines are thus being pursued: The application and development of quantification methods for blood serum non-transferrin-bound iron (NTBI). I also, try to increase knowledge about the biochemical nature of these elusive NTBI species. I have also been applying my expertise in MS and MS based proteomics in a series of collaborations which range from the characterization of biomarkers in bladder cancer to metabolite identification in composite drugs. Show less
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REQUIMTE-LAQV
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Porto Area, Portugal
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Research Associate
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Jun 2013 - Present
The area of scientific activity is Biochemistry and Chemical Biology. Particular interests are the study of systemic iron transport in the blood plasma and the study of protein biochemistry, especially non-enzymatic post-translational modifications such as oxidation and glycation. Domain of specialization Biochemistry and Chemical Biology Inorganic Biochemistry of Iron Mass Spectrometry Proteomics The area of scientific activity is Biochemistry and Chemical Biology. Particular interests are the study of systemic iron transport in the blood plasma and the study of protein biochemistry, especially non-enzymatic post-translational modifications such as oxidation and glycation. Domain of specialization Biochemistry and Chemical Biology Inorganic Biochemistry of Iron Mass Spectrometry Proteomics
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QOPNA/ LAQV-REQUIMTE
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Portugal
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Research Services
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1 - 100 Employee
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Post-Doctoral Researcher
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Jan 2010 - May 2013
Post-dosctoral position at the Mass Spectrometry Centre, University of Aveiro Supervision: Pedro Domingues Post-dosctoral position at the Mass Spectrometry Centre, University of Aveiro Supervision: Pedro Domingues
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REQUIMTE- Department of Chemistry
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Porto Area, Portugal
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Graduate Research Assistant
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Jan 2005 - Jan 2006
Position in Professor Maria Rangel Laboratory Position in Professor Maria Rangel Laboratory
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Aarhus University
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Denmark
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Research
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700 & Above Employee
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BSc in Biochemistry, Final Year Internship
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Feb 2004 - Aug 2004
BSc in Biochemistry - Final Year Internship Title: Isolation and Further Characterization of the New Eukaryotic Elongation Factor 1 A2 Binding Protein Supervision: Charlotte R. Knudsen Institute of Molecular and Structural Biology, Aarhus University, Denmark (As part of the Erasmus program) BSc in Biochemistry - Final Year Internship Title: Isolation and Further Characterization of the New Eukaryotic Elongation Factor 1 A2 Binding Protein Supervision: Charlotte R. Knudsen Institute of Molecular and Structural Biology, Aarhus University, Denmark (As part of the Erasmus program)
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Education
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King's College London
Doctor of Philosophy - PhD, Pharmaceutical Sciences -
Universidade do Porto
Bachelor of Science - BS, Biochemistry -
Escola Secundária D. Dinis - Sto Tirso
Científico-Natural