Andrew Hsieh

Undergraduate Researcher at Waksman Institute of Microbiology
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Contact Information
us****@****om
(386) 825-5501
Languages
  • Chinese Limited working proficiency
  • Italian Limited working proficiency

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Bio

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Experience

    • Biotechnology Research
    • 1 - 100 Employee
    • Undergraduate Researcher
      • Sep 2020 - Present

      • Maintaining and inoculating cultures of gene knockout mutant cyanobacteria (Synechococcus 7002) while optimizing PCR procedures for genetic confirmation. • Designed assays to quantify protein, lipid, and glycogen content in cell biomass, and assembled/tested benchtop photobioreactors for continuous, scaled-up growth and monitoring of cultures. • Working to quantify cell physiology of mutant cultures through metabolic flux analysis, using isotope labeling and extracellular flux measurements. • Helped development of a computational ordinary differential equation model of photosystem II (PSII) electron transport kinetics using MATLAB to simulate chlorophyll fluorescence and PSII efficiency, fitting experimental data to study the parameters and origins of Fv/Fm oscillations. • Presented results and data regularly at lab group meetings and in poster sessions, including the 2022 Waksman Institute Annual Retreat and the 2021 Aresty Undergraduate Research Virtual Symposium.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Manufacturing and Quality Intern, QC Analytics
      • May 2022 - Aug 2022

      • Authored study protocol to evaluate comparability between the use of different HPLC systems for analytical purity testing of cetuximab (ERBITUX®) drug product as a continuous improvement opportunity to expand laboratory capabilities at Lilly Branchburg Quality Control Labs (BB QCL). • Incorporated feedback from Subject Matter Experts across Lilly Technical Services/Manufacturing Science and Quality functions to implement design of experiment and study acceptance criteria before guiding document to approval. • Completed Four Phase Skills-Based Training on Size Exclusion High Performance Liquid Chromatography (SE HPLC) as well as lab equipment and local procedures to meet standards of GMP, Safety, and Quality Assurance at BB QCL. • Executed comparability study protocol in GMP QC lab environment, generated and submitted lab data for processing and report. Study results will justify usage of different systems and provide greater flexibility for analytical testing at BB QCL. • Delivered formal presentation on project achievements to Manufacturing and Quality Site Lead Team.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Manufacturing Intelligence PAT Intern
      • May 2021 - Aug 2021

      • Assisted with development and implementation of cutting-edge Process Analytical Technology (PAT) measurement systems for API detection, cleaning validation, and tablet coating applications within Manufacturing Intelligence and Global Technology & Engineering • Monitored and evaluated instrument performance while installing and configuring spectroscopy software, with hands-on experience working with UV/Vis and Raman Spectroscopy analyzers at Pfizer's Process Monitoring, Automation and Control (PMAC) lab • Conducted market research and evaluation of automation solutions in laboratory and pharmaceutical manufacturing, reached out to and arranged meetings with leading global pharmaceutical automation and collaborative robotics companies • Submitted company reports and presented lab results to Pfizer Manufacturing Intelligence senior leadership

    • United States
    • Manufacturing
    • 700 & Above Employee
    • Regulatory Affairs Extern
      • Sep 2020 - Dec 2020

      • Analyzed regulatory process data and researched FDA OTC monographs to prototype a regulatory AI tool with InVision, with the goal of simplifying new cosmetic and drug product registration to make information accessible for non-regulatory departments • Conducted internal interviews to identify common pain points in the regulatory process and incorporate practical solutions • Communicated and collaborated with team and regulatory affairs personnel, gaining professional teamwork and industry experience • Presented functional AI tool prototype to Colgate-Palmolive Regulatory senior leadership

    • United States
    • Education Administration Programs
    • 700 & Above Employee
    • Mathematics Instructor
      • Aug 2018 - Sep 2020

      • Trained middle/high school students to build confidence in their math abilities with personalized homework and test prep • Attained high level of communication through close interaction with students to maintain a positive learning environment • Trained middle/high school students to build confidence in their math abilities with personalized homework and test prep • Attained high level of communication through close interaction with students to maintain a positive learning environment

Education

  • Rutgers University–New Brunswick
    Bachelor's degree, Chemical and Biochemical Engineering | Biological Sciences
    2019 - 2023
  • Parsippany High School
    2015 - 2019

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