Experience

Decibel Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Director, Informatics

  • Oct 2022 - Present

  Boston, Massachusetts, United States - Managing of all functions of Research Informatics including procurement and support of research software, data mesh, all AWS and GCP cloud services, vendor contracts and budget. - Providing day to day informatics services for the R&D teams on a request-driven, collaborative or educational basis depending on the project. - Support and maintenance of all analytical software systems used by the R&D teams - Championing of deeper Benchling, Quilt and AI adoption within the… Show more - Managing of all functions of Research Informatics including procurement and support of research software, data mesh, all AWS and GCP cloud services, vendor contracts and budget. - Providing day to day informatics services for the R&D teams on a request-driven, collaborative or educational basis depending on the project. - Support and maintenance of all analytical software systems used by the R&D teams - Championing of deeper Benchling, Quilt and AI adoption within the company. - Actively reducing manual and inefficient processes: automating where possible. - Collaborating with QA and clinical groups on data integrity and storage best practices. - Actively working to drive down costs of data analysis and storage. - Custom tool development (web / GUI / Python / Bash) - Data analysis pipeline development and maintenance Show less



Sema4

• United States
• Biotechnology Research
• 200 - 300 Employee

• Director, Analytical Methods

  • May 2020 - Oct 2022

  Stamford, Connecticut, United States - Led, motivated, and nurtured a team of 8 bioinformaticians, biostatisticians and software engineers. - Provided bespoke analytical bioinformatics support and coordinated investigation into data quality anomalies and cryptic pipeline failures. - Provided bioinformatics support for clinical test development and validation. - Oversaw clinical validations of reagents and equipment and participated in clinical test validation. - Improved the efficiency of daily routine… Show more - Led, motivated, and nurtured a team of 8 bioinformaticians, biostatisticians and software engineers. - Provided bespoke analytical bioinformatics support and coordinated investigation into data quality anomalies and cryptic pipeline failures. - Provided bioinformatics support for clinical test development and validation. - Oversaw clinical validations of reagents and equipment and participated in clinical test validation. - Improved the efficiency of daily routine analysis tasks, reducing analysis time by up to 300%. - Collaborated extensively with project managers, clinical directors, and teams across the organization. - Co-led an “assay health” initiative to improve sample QC monitoring, reduce failure rate, reduce sample turnaround time and costs.

• Director Of Bioinformatics (Germline)

  • Jun 2017 - Apr 2020

  New York, New York - Led bioinformatics support for our flagship germline test portfolio. Responsible for ensuring that every patient sample completed the bioinformatics pipelines successfully whilst respecting turnaround time. - Participated in clinical germline test development and ensured that work satisfied CAP and NYS regulatory requirements, including writing SOPs and policies, and providing support for inspections. - Provided production pipeline support and custom bioinformatics analysis for… Show more - Led bioinformatics support for our flagship germline test portfolio. Responsible for ensuring that every patient sample completed the bioinformatics pipelines successfully whilst respecting turnaround time. - Participated in clinical germline test development and ensured that work satisfied CAP and NYS regulatory requirements, including writing SOPs and policies, and providing support for inspections. - Provided production pipeline support and custom bioinformatics analysis for lab directors and technology innovation. - Calmly directed, under pressure, a remote war-room when a critical bioinformatics system failed during the weekend, requiring a system rebuild. Successfully restored normal operation.



Icahn School of Medicine at Mount Sinai

• United States
• Hospitals and Health Care
• 700 & Above Employee

• Adjunct Assistant Professor

  • Nov 2018 - Oct 2022

  New York, New York

• Assistant Professor

  • Mar 2015 - Oct 2018

  New York, New York - Developed NGS data analysis pipelines and dashboard web apps under tight deadlines which facilitated a 1500% ramp-up in sample volume within a month after deployment. - Led bioinformatics support for our flagship germline test portfolio. Responsible for ensuring that every patient sample completed the bioinformatics pipelines successfully whilst respecting turnaround time. - Participated in clinical germline test development and ensured that work satisfied CAP and NYS… Show more - Developed NGS data analysis pipelines and dashboard web apps under tight deadlines which facilitated a 1500% ramp-up in sample volume within a month after deployment. - Led bioinformatics support for our flagship germline test portfolio. Responsible for ensuring that every patient sample completed the bioinformatics pipelines successfully whilst respecting turnaround time. - Participated in clinical germline test development and ensured that work satisfied CAP and NYS regulatory requirements, including writing SOPs and policies, and providing support for inspections. - Provided production pipeline support and custom bioinformatics analysis for lab directors and technology innovation team in the Genetic Testing Laboratory.



Albert Einstein College of Medicine

• United States
• Higher Education
• 700 & Above Employee

• Associate Faculty

  • May 2009 - Feb 2015

  - Led development of an end-to-end modular LIMS written primarily in Java, leveraging the Spring framework and HPC infrastructure. Handled over 8,000 NGS samples submitted by over 200 labs. - Custom bioinformatics analysis for Einstein researchers.



Ericsson

• Sweden
• Telecommunications
• 700 & Above Employee

• Software Developer

  • Sep 2008 - Apr 2009

  Served as integral member of highly skilled and motivated team developing and maintaining real-time C++ software to facilitate handling of 3G (WCDMA) mobile phone calls. Undertook personal responsibility for design impacts on three critically important blocks of production code, handling call traffic and resource allocation, maintained according to measured standards and design rule documentation. Participated in team code reviews and process improvement drives. Delivered new software features… Show more Served as integral member of highly skilled and motivated team developing and maintaining real-time C++ software to facilitate handling of 3G (WCDMA) mobile phone calls. Undertook personal responsibility for design impacts on three critically important blocks of production code, handling call traffic and resource allocation, maintained according to measured standards and design rule documentation. Participated in team code reviews and process improvement drives. Delivered new software features on time according to fixed schedules. Show less



University College Cork

• Ireland
• Higher Education
• 700 & Above Employee

• Post Doc

  • Jun 2002 - Jul 2006

  Worked primarily on bioinformatics-based projects, including development of bespoke Perl programs to investigate comparative molecular evolution of pregnancy-specific glycoprotein multi-gene families in rodents and primates. Developed Perl and C++ programs to provide data wrangling and statistical analysis of data generated during SNP-based investigation into genetics of autism.