Amy Mandigo

Senior Scientist at Regeneron
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Contact Information
us****@****om
(386) 825-5501
Location
New York City Metropolitan Area

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Experience

    • United States
    • Biotechnology
    • 700 & Above Employee
    • Senior Scientist
      • Mar 2023 - Present

    • Associate Scientist
      • Sep 2021 - Mar 2023

    • United States
    • Higher Education
    • 700 & Above Employee
    • PHD Candidate
      • Aug 2014 - Aug 2021

      - Identified a new subset of castration-resistance prostate cancer that responds poorly to cytotoxic therapy. - Discovered a novel role for the retinoblastoma tumor suppressor protein (RB) in the regulation of cancer cell metabolism through negative control of the E2F1 transcription factor in advanced castration-resistant prostate cancer. - Elucidated the mechanism of the androgen receptor and E2F1 co-regulation of cancer-related transcription. - Identified a new subset of castration-resistance prostate cancer that responds poorly to cytotoxic therapy. - Discovered a novel role for the retinoblastoma tumor suppressor protein (RB) in the regulation of cancer cell metabolism through negative control of the E2F1 transcription factor in advanced castration-resistant prostate cancer. - Elucidated the mechanism of the androgen receptor and E2F1 co-regulation of cancer-related transcription.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Information Technology Helpdesk Support
      • Dec 2011 - Aug 2014

      - Coordinated between customers and several departments within Information Technology regarding computer hardware and software troubleshooting and service requests - Managed and trained new employees in assisting customers, submitting reports, and resolving issues - Developed a training program and manual for all new employees - Coordinated between customers and several departments within Information Technology regarding computer hardware and software troubleshooting and service requests - Managed and trained new employees in assisting customers, submitting reports, and resolving issues - Developed a training program and manual for all new employees

Education

  • Thomas Jefferson University Hospitals
    PhD in Biochemistry and Molecular Pharmacology, Cancer Biology
    2014 - 2021
  • Marist College
    Bachelor of Science (B.S.), Chemistry/Biochemistry
    2010 - 2014

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