Amit Singh
Scientist -D at National Jalma Institute of Leprosy And Other Mycobacterial Diseases- Claim this Profile
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Bio
Credentials
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PGDIPR
Indira Gandhi National Open University (IGNOU)
Experience
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National Jalma Institute of Leprosy And Other Mycobacterial Diseases
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Higher Education
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1 - 100 Employee
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Scientist -D
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Sep 2020 - Present
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Scientist C
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Dec 2017 - Jun 2022
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Scientist C
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Jun 2016 - Dec 2017
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Jeju National University
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Biotechnology
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1 - 100 Employee
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Postdoctoral Research Fellow
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Jul 2015 - Mar 2016
Working in the area of cancer biology on development of immunotherapy for targeting cancer stem cells (CSCs). Simultaneously, also working on evaluation of phytochemicals efficacy for inhibiting CSCs growth. Working in the area of cancer biology on development of immunotherapy for targeting cancer stem cells (CSCs). Simultaneously, also working on evaluation of phytochemicals efficacy for inhibiting CSCs growth.
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Guru Angad Dev Veterinary & Animal Sciences University, Ludhiana
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India
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Higher Education
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1 - 100 Employee
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Assistant Toxicologist
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Sep 2013 - Jun 2015
Working as research scholar on development of drug delivery system for veterinary purpose and also interested in elucidating immunological responses following infection and its modulation following drug treatment. Mentor and Supervisor: Prof. Suresh Sharma, PhD, Professor cum Head, Guru Angad Dev Veterinary & Animal Science University, Ludhiana, India. Working as research scholar on development of drug delivery system for veterinary purpose and also interested in elucidating immunological responses following infection and its modulation following drug treatment. Mentor and Supervisor: Prof. Suresh Sharma, PhD, Professor cum Head, Guru Angad Dev Veterinary & Animal Science University, Ludhiana, India.
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Department Of Biotechnology, Government Of india
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India
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Biotechnology Research
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1 - 100 Employee
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Consultant
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May 2012 - Aug 2013
Involved in Tuberculosis research program, reviewing research proposals received, involved in clinical trials, working in close co-ordination with leading scientists involved in TB research, Involved in Tuberculosis research program, reviewing research proposals received, involved in clinical trials, working in close co-ordination with leading scientists involved in TB research,
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Central Drug Research Institute, Lucknow
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Pharmaceutical Manufacturing
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300 - 400 Employee
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Senior Research Fellow
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Aug 2008 - Oct 2012
My thesis addressed host-pathogen interactions in tuberculosis (TB) in the context of the genetic background of the human host, and the effect of drug treatment on these interactions. We investigated whether in vitro infection of primary human monocyte-derived macrophages with Mycobacterium tuberculosis results in differences in host gene expression and bacterial survival in the presence and absence of drug treatment. A novel drug delivery system comprising inhalable, biodegradable… Show more My thesis addressed host-pathogen interactions in tuberculosis (TB) in the context of the genetic background of the human host, and the effect of drug treatment on these interactions. We investigated whether in vitro infection of primary human monocyte-derived macrophages with Mycobacterium tuberculosis results in differences in host gene expression and bacterial survival in the presence and absence of drug treatment. A novel drug delivery system comprising inhalable, biodegradable microparticles was also evaluated for its ability to affect host response in addition to targeting anti-TB drugs to macrophages. Mentor: Dr. Amit Misra, PhD, Principal Scientist cum Head, Pharmaceutics Division, CDRI, (India).
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Junior Research Fellow
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Aug 2006 - Aug 2008
Carried out Yeast two hybrid assay to identify the host protein interacting with M.tuberculosis virulent gene. Also did gene cloning, protein purification, western blotting experiments.
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Education
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Central Drug Research institute
Doctor of Philosophy (PhD), Host pathogen interaction in tuberculosis and drug delivery system -
National Dairy Research Institute
M.V.Sc., Animal Biotechnology -
College of Veterinary Science & animal husbandry, Anjora, Durg
B.V.Sc.&A.H, Veterinary Science -
St. Joseph Convent School