Amit Singh

Scientist -D at National Jalma Institute of Leprosy And Other Mycobacterial Diseases
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Contact Information
us****@****om
(386) 825-5501
Location
Delhi, India, IN

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Credentials

  • PGDIPR
    Indira Gandhi National Open University (IGNOU)

Experience

    • Scientist -D
      • Sep 2020 - Present
    • Scientist C
      • Jun 2016 - Dec 2017
    • Biotechnology
    • 1 - 100 Employee
    • Postdoctoral Research Fellow
      • Jul 2015 - Mar 2016

      Working in the area of cancer biology on development of immunotherapy for targeting cancer stem cells (CSCs). Simultaneously, also working on evaluation of phytochemicals efficacy for inhibiting CSCs growth. Working in the area of cancer biology on development of immunotherapy for targeting cancer stem cells (CSCs). Simultaneously, also working on evaluation of phytochemicals efficacy for inhibiting CSCs growth.

    • Assistant Toxicologist
      • Sep 2013 - Jun 2015

      Working as research scholar on development of drug delivery system for veterinary purpose and also interested in elucidating immunological responses following infection and its modulation following drug treatment. Mentor and Supervisor: Prof. Suresh Sharma, PhD, Professor cum Head, Guru Angad Dev Veterinary & Animal Science University, Ludhiana, India. Working as research scholar on development of drug delivery system for veterinary purpose and also interested in elucidating immunological responses following infection and its modulation following drug treatment. Mentor and Supervisor: Prof. Suresh Sharma, PhD, Professor cum Head, Guru Angad Dev Veterinary & Animal Science University, Ludhiana, India.

    • India
    • Biotechnology Research
    • 1 - 100 Employee
    • Consultant
      • May 2012 - Aug 2013

      Involved in Tuberculosis research program, reviewing research proposals received, involved in clinical trials, working in close co-ordination with leading scientists involved in TB research, Involved in Tuberculosis research program, reviewing research proposals received, involved in clinical trials, working in close co-ordination with leading scientists involved in TB research,

    • Pharmaceutical Manufacturing
    • 300 - 400 Employee
    • Senior Research Fellow
      • Aug 2008 - Oct 2012

      My thesis addressed host-pathogen interactions in tuberculosis (TB) in the context of the genetic background of the human host, and the effect of drug treatment on these interactions. We investigated whether in vitro infection of primary human monocyte-derived macrophages with Mycobacterium tuberculosis results in differences in host gene expression and bacterial survival in the presence and absence of drug treatment. A novel drug delivery system comprising inhalable, biodegradable… Show more My thesis addressed host-pathogen interactions in tuberculosis (TB) in the context of the genetic background of the human host, and the effect of drug treatment on these interactions. We investigated whether in vitro infection of primary human monocyte-derived macrophages with Mycobacterium tuberculosis results in differences in host gene expression and bacterial survival in the presence and absence of drug treatment. A novel drug delivery system comprising inhalable, biodegradable microparticles was also evaluated for its ability to affect host response in addition to targeting anti-TB drugs to macrophages. Mentor: Dr. Amit Misra, PhD, Principal Scientist cum Head, Pharmaceutics Division, CDRI, (India).

    • Junior Research Fellow
      • Aug 2006 - Aug 2008

      Carried out Yeast two hybrid assay to identify the host protein interacting with M.tuberculosis virulent gene. Also did gene cloning, protein purification, western blotting experiments.

Education

  • Central Drug Research institute
    Doctor of Philosophy (PhD), Host pathogen interaction in tuberculosis and drug delivery system
    2006 - 2012
  • National Dairy Research Institute
    M.V.Sc., Animal Biotechnology
    2004 - 2006
  • College of Veterinary Science & animal husbandry, Anjora, Durg
    B.V.Sc.&A.H, Veterinary Science
    1998 - 2003
  • St. Joseph Convent School
    1991 - 1994

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