Experience

Sino Biological, Inc.

• China
• Biotechnology Research
• 1 - 100 Employee

• Head, Product and Marketing Department

  • Jun 2023 - Present

• Head, Product Department

  • Jul 2022 - Present

  Houston, Texas, United Stateas

• Product Manager

  • Jun 2021 - Jul 2022



Frontiers in Pharmacology

• Guest Editor

  • Oct 2018 - Present

  Lausanne Area, Switzerland Topic Editor: “Resistance to Immunotherapy: A Challenge of Cancer Treatment”; Journal of oncology. Impact Factor: 3.55 https://www.hindawi.com/journals/jo/si/708536/cfp/



Filtricine, Inc.

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist II

  • Aug 2020 - Jul 2021

  Sunnyvale, California, United States

• Scientist II

  • May 2019 - Jul 2020

  Sunnyvale, California, United States Research on cancer metabolism and novel therapeutic development (IND enabling efficacy, safety, and toxicology studies) Project management and coordination with CROs Medical writing and Grant writing Clinical Trial Coordination Patient communication and coordination (HIPAA certified)



Journal of Oncology

• Guest Editor

  • Dec 2018 - May 2019

  London, United Kingdom Topic Editor: “Resistance to Immunotherapy: A Challenge of Cancer Treatment”; Journal of oncology. Impact Factor: 3.55 https://www.hindawi.com/journals/jo/si/708536/cfp/



University of Houston

• United States
• Higher Education
• 700 & Above Employee

• Research Associate

  • Jun 2018 - May 2019

  • Responsible for creating, optimizing, and performing the On-Bead Two-Color (OBTC) Cell Screen for direct identification of highly selective cell surface receptor targeting peptoid compounds • Worked on the mechanistic study of the epigenetic modulating small molecule (TET2 activator) in cancer cells • Worked on the production and purification of His-tagged recombinant EZH2 protein • Responsible for xenograft mouse model and drug efficacy in vivo assays • Responsible for in depth… Show more • Responsible for creating, optimizing, and performing the On-Bead Two-Color (OBTC) Cell Screen for direct identification of highly selective cell surface receptor targeting peptoid compounds • Worked on the mechanistic study of the epigenetic modulating small molecule (TET2 activator) in cancer cells • Worked on the production and purification of His-tagged recombinant EZH2 protein • Responsible for xenograft mouse model and drug efficacy in vivo assays • Responsible for in depth data analysis, interpretation, and presentation for genomic, epigenomic, and transcriptomic data (RNA sequencing and ChIP sequencing data) • Generated data summaries for potential publication using common data analysis software • Responsible for the performing and training of graduate students on the design, development, optimization, and performance of various molecular biological techniques (e.g. western blotting, ELISA, molecular cloning, CRISPR, etc.) • Responsible for addressing methodological problems in experimental protocols and results • Engaged in the writing of manuscripts and grants Show less



Beth Israel Deaconess Medical Center

• United States
• Hospitals and Health Care
• 700 & Above Employee

• Research Fellow

  • Mar 2017 - Jun 2018

  Greater Boston Area • Worked on the mechanistic study of modulating PDGFR signaling and protein translation initiation in Glioblastoma • Established primary cell cultures; maintained and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Performed routine transgenic mouse colony breeding, genotyping, and maintenance • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques… Show more • Worked on the mechanistic study of modulating PDGFR signaling and protein translation initiation in Glioblastoma • Established primary cell cultures; maintained and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Performed routine transgenic mouse colony breeding, genotyping, and maintenance • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques (e.g. western blotting, qPCR, molecular cloning, flow cytometry, etc.) based on the requirement of research projects • Responsible for in depth data analysis, interpretation, and presentation for large scale proteomics/phosphor-proteomics data • Established signaling pathway maps with extensive details using Cell Designer software • Performed visualization of gene/protein interactions using Cytoscape software • Performed isolation of exosomes from cell cultures; extraction and quantification (qPCR) of miRNAs from exosomes • Engaged in the writing of manuscripts and grants Show less



Harvard Medical School

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Fellow

  • Mar 2017 - Jun 2018

  Greater Boston Area • Worked on the mechanistic study of modulating PDGFR signaling and protein translation initiation in Glioblastoma • Established primary cell cultures; maintained and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Performed routine transgenic mouse colony breeding, genotyping, and maintenance • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques… Show more • Worked on the mechanistic study of modulating PDGFR signaling and protein translation initiation in Glioblastoma • Established primary cell cultures; maintained and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Performed routine transgenic mouse colony breeding, genotyping, and maintenance • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques (e.g. western blotting, qPCR, molecular cloning, flow cytometry, etc.) based on the requirement of research projects • Responsible for in depth data analysis, interpretation, and presentation for large scale proteomics/phosphor-proteomics data • Established signaling pathway maps with extensive details using Cell Designer software • Performed visualization of gene/protein interactions using Cytoscape software • Performed isolation of exosomes from cell cultures; extraction and quantification (qPCR) of miRNAs from exosomes • Engaged in the writing of manuscripts and grants Show less



Baylor Scott & White Health

• United States
• Hospitals and Health Care
• 700 & Above Employee

• Postdoctoral Fellow

  • Jan 2016 - Mar 2017

  Killeen/Temple, Texas Area • Worked on the mechanistic study of small molecule cancer stem cell inhibitor and traditional Chinese medicinal drugs for the use in neuroblastoma, brain cancer, and pancreatic cancer • Worked on the identification of novel treatments for Alzheimer's disease (AD) • Performed experiments for validation of novel biomarkers (e.g. new biomarker panel for glioblastoma) for cancer diagnosis and better understanding of cancer progression • Established and used genetically engineered cell… Show more • Worked on the mechanistic study of small molecule cancer stem cell inhibitor and traditional Chinese medicinal drugs for the use in neuroblastoma, brain cancer, and pancreatic cancer • Worked on the identification of novel treatments for Alzheimer's disease (AD) • Performed experiments for validation of novel biomarkers (e.g. new biomarker panel for glioblastoma) for cancer diagnosis and better understanding of cancer progression • Established and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques (e.g. western blotting, ELISA, molecular cloning, CRISPR, etc.) based on the requirement of research projects • Responsible for training of graduate students, visiting scholars, and summer students • Responsible for in depth data analysis, interpretation, and presentation for established genomic databases • Engaged in the writing of manuscripts and grants Show less



North Dakota State University

• United States
• Higher Education
• 700 & Above Employee

• Teaching Assistant

  • Jan 2012 - Dec 2015

  • Teaching assistant for the course “Pharmacogenomics” and taught the “Methodologies and Applied Bioinformatics” part of the course, (1 semester); course “Chemotherapeutic/Infectious Disease Pharmacodynamics” (4 semesters); course “Principles of Pharmacokinetics and Pharmacodynamics” (1 semester)

• Research Assistant

  • Aug 2010 - Dec 2015

  • Worked on the mechanistic study of small molecule cancer stem cell inhibitor and the identification of its drug binding targets using enzymatic methods and proteomics • Evaluated the use of traditional Chinese medicinal drugs for the treatment of neuroblastoma, brain cancer, and pancreatic cancer using molecular biological techniques • Worked on the identification of novel treatments for Alzheimer's disease (AD) • Evaluated the TDP-43(A315T) mutation as a quick diagnostic biomarker… Show more • Worked on the mechanistic study of small molecule cancer stem cell inhibitor and the identification of its drug binding targets using enzymatic methods and proteomics • Evaluated the use of traditional Chinese medicinal drugs for the treatment of neuroblastoma, brain cancer, and pancreatic cancer using molecular biological techniques • Worked on the identification of novel treatments for Alzheimer's disease (AD) • Evaluated the TDP-43(A315T) mutation as a quick diagnostic biomarker for neurodegenerative disease and examined the mechanisms for TDP43 induced neuronal toxicity • Examined the roles of signaling pathways (e.g. PDGFR, EGFR, PI3K/ERK signaling) in the pathological process and treatment of cancer • Worked on the identification of the new applications of a few drugs in cancers, such as Docosahexaenoic Acid (DHA), Vitamin D, salinomycin, and thalidomide • Established and used genetically engineered cell cultures and immortalized human cell lines for genetic and molecular analyses • Analyzed cancer cells based on cell surface markers (CD133, CD34, c-kit, etc.) for cell separation and characterization using flow cytometry • Responsible for performing the design, development, optimization, and performance of various molecular biological techniques (e.g. western blotting, ELISA, molecular cloning, CRISPR, etc.) based on the requirement of research projects • Responsible for training of graduate students and summer students • Responsible for in depth data analysis, interpretation, and presentation for internal meetings and national conferences • Responsible for the maintenance of the Flow cytometry machine, and the training for fellow students for the use of flow cytometer. • Engaged in the writing of manuscripts and grants

• Ph.D. student

  • Jul 2010 - Dec 2015

  Fargo, North Dakota, United States



Centers of Disease Control and Prevention

• Summer Intern

  • 2006 - 2009

  Chifeng, Inner Mongolia, China Attended the prevention and control work of some diseases, such as AIDS and Hand-foot-mouth disease; Studied the operation of certain software, especially China Information System for Diseases Control and Prevention; Visited some hospitals, patients and schools to take part in works as disease diagnoses, medicine analysis and care of patients.