Ambily Sivadas

Post Doctoral Fellow at St Johns Research Institute
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Contact Information
us****@****om
(386) 825-5501
Location
Bengaluru, Karnataka, India, IN

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Experience

    • India
    • Research Services
    • 1 - 100 Employee
    • Post Doctoral Fellow
      • Mar 2019 - Present
    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Scientist
      • Jan 2013 - Jun 2013

      Novel biomarker discovery and identification of gene-metabolite networks by integrating human genomics with metabolomics: Developing a novel4-way cross-correlation method to combine genotype, gene expression, metabolomic data and clinical trait information to reveal novel gene-metabolite networks of clinical importance

    • Graduate Research Assistant
      • Jan 2012 - Dec 2012

      The WHOLE Study (An approach to personalized medicine through deep integrative profiling): Worked on developing an efficient and accurate clinico-genomic model that can generate disease risk scores for healthy individuals through integrative analysis of longitudinal multiple omics data (genomic, transcriptomic, epigenetic) in light of their clinical measurements

    • United States
    • Biotechnology
    • 700 & Above Employee
    • Summer Intern
      • May 2012 - Aug 2012

      Development and Deployment of NGS Data Analysis Pipeline: Implemented an NGS data analysis pipeline to evaluate the efficiency of a Zinc Finger Nuclease gene modification toolkit and deployed an ASP.Net Web application using MySQL database to perform real-time execution of the pipeline on a super-computing cluster environment and analyze the results through a web portal Development and Deployment of NGS Data Analysis Pipeline: Implemented an NGS data analysis pipeline to evaluate the efficiency of a Zinc Finger Nuclease gene modification toolkit and deployed an ASP.Net Web application using MySQL database to perform real-time execution of the pipeline on a super-computing cluster environment and analyze the results through a web portal

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Software Engineer - BioInformatics
      • Jul 2008 - Jul 2011

      Designed and implemented an indigenous Sequence-based Allele Search Algorithm for efficient and optimized search of homozygous as well as heterozygous allele sequences to identify New Allele occurrence in the HLA gene  Conceptualized and automated the process of high volume New Allele submission to GenBank using TBL2ASN tool and to WHO Nomenclature Committee to get allele designations for new alleles discovered by Histogenetics  Led a team of two for the development of In-house… Show more Designed and implemented an indigenous Sequence-based Allele Search Algorithm for efficient and optimized search of homozygous as well as heterozygous allele sequences to identify New Allele occurrence in the HLA gene  Conceptualized and automated the process of high volume New Allele submission to GenBank using TBL2ASN tool and to WHO Nomenclature Committee to get allele designations for new alleles discovered by Histogenetics  Led a team of two for the development of In-house web-enabled software support that captures every stage of the laboratory-oriented work flow involved in the HLA typing process  Designed and implemented a Task Scheduler program (ASP.NET –SQLSERVER) which automates task planning and scheduling activity in the laboratory for various experimental processes thereby achieving process improvement  Upgraded the HLA genetic data processing and reporting system to adopt the latest Allele Nomenclature  Designed and implemented an algorithm to identify HLA haplotypes using the huge HLA typing database Show less Designed and implemented an indigenous Sequence-based Allele Search Algorithm for efficient and optimized search of homozygous as well as heterozygous allele sequences to identify New Allele occurrence in the HLA gene  Conceptualized and automated the process of high volume New Allele submission to GenBank using TBL2ASN tool and to WHO Nomenclature Committee to get allele designations for new alleles discovered by Histogenetics  Led a team of two for the development of In-house… Show more Designed and implemented an indigenous Sequence-based Allele Search Algorithm for efficient and optimized search of homozygous as well as heterozygous allele sequences to identify New Allele occurrence in the HLA gene  Conceptualized and automated the process of high volume New Allele submission to GenBank using TBL2ASN tool and to WHO Nomenclature Committee to get allele designations for new alleles discovered by Histogenetics  Led a team of two for the development of In-house web-enabled software support that captures every stage of the laboratory-oriented work flow involved in the HLA typing process  Designed and implemented a Task Scheduler program (ASP.NET –SQLSERVER) which automates task planning and scheduling activity in the laboratory for various experimental processes thereby achieving process improvement  Upgraded the HLA genetic data processing and reporting system to adopt the latest Allele Nomenclature  Designed and implemented an algorithm to identify HLA haplotypes using the huge HLA typing database Show less

Education

  • CSIR-Institute of Genomics and Integrative Biology
    Doctor of Philosophy (Ph.D.), Bioinformatics, and Computational Biology
    2013 - 2018
  • Georgia Institute of Technology
    Master's degree, Bioinformatics
    2011 - 2012
  • Birla Institute of Technology and Science, Pilani
    MSc(Hons) Biological Science with BE (Hons) Computer Science, BioInformatics
    2003 - 2008

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