Amanda Kedaigle

Principal Scientist, Associate Director, Molecular Innovation – Systems Biology at Decibel Therapeutics
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Contact Information
us****@****om
(386) 825-5501
Location
Greater Boston

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Credentials

  • From the Laboratory to Leadership
    The Leadership Edge
    Apr, 2023
    - Nov, 2024
  • Graduate Education in Medical Sciences
    Harvard-MIT Health Sciences & Technology
    Jan, 2015
    - Nov, 2024

Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Principal Scientist, Associate Director, Molecular Innovation – Systems Biology
      • Jul 2023 - Present

    • Senior Scientist, Computational Biology
      • Jul 2022 - Jun 2023

    • Bioinformatics Analyst
      • Sep 2017 - Jul 2023

      Volunteer work for a cancer research non-profit, leveraging RNA sequencing data to study a rare cancer Volunteer work for a cancer research non-profit, leveraging RNA sequencing data to study a rare cancer

    • Research Services
    • 700 & Above Employee
    • Computational Scientist II
      • Jul 2021 - Jul 2022

      A member of Joshua Levin's group at the Stanley Center and Paola Arlotta's group at Harvard University, studying neuropsychiatric disorders through single cell data analysis of brain organoids.

    • Computational Scientist I
      • Jul 2018 - Jun 2021

    • United States
    • Higher Education
    • 700 & Above Employee
    • PhD Research
      • Sep 2012 - Jun 2018

      Worked with Dr. Ernest Fraenkel to study Huntington's Disease through the development and use of computational and systems biology tools. Created the Omics Integrator tool which allows for network-based analysis of multiple omics datasets. Applied the tool to data procured from iPSC-derived neuronal models of HD to identify novel proteins and pathways that impact the disease. Worked with Dr. Ernest Fraenkel to study Huntington's Disease through the development and use of computational and systems biology tools. Created the Omics Integrator tool which allows for network-based analysis of multiple omics datasets. Applied the tool to data procured from iPSC-derived neuronal models of HD to identify novel proteins and pathways that impact the disease.

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Translational Research Preceptorship
      • Nov 2015 - Feb 2016

      Worked with Dr. Anne Louise Oaklander during treatment and study of Small Fiber Polyneuropathy, an understudied chronic pain disorder. Created software tools to track patient symptoms. Worked with Dr. Anne Louise Oaklander during treatment and study of Small Fiber Polyneuropathy, an understudied chronic pain disorder. Created software tools to track patient symptoms.

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Intern
      • Sep 2013 - Nov 2013

      Research Intern at Merrimack Pharmaceuticals. Analyzed Next-Gen Sequencing data and applied results to the search for cancer therapies. Research Intern at Merrimack Pharmaceuticals. Analyzed Next-Gen Sequencing data and applied results to the search for cancer therapies.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Researcher
      • Sep 2009 - Aug 2012

      Undergraduate research in Don Elmore's lab on computational modeling of hypothetical structures for the novel protein Patellin1. Undergraduate research in Don Elmore's lab on computational modeling of hypothetical structures for the novel protein Patellin1.

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Intern
      • Jun 2010 - Aug 2010

      Worked with Kathrin Bernt in Scott Armstrong's Lab researching genetic causes of MLL leukemias. Worked with Kathrin Bernt in Scott Armstrong's Lab researching genetic causes of MLL leukemias.

Education

  • Massachusetts Institute of Technology
    Doctor of Philosophy (PhD), Computational Biology
    2012 - 2018
  • Wellesley College
    BA, Bioinformatics
    2008 - 2012

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