Alexey Poyarkov
Head of Physicochemical Lab at Life Chemicals- Claim this Profile
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English Full professional proficiency
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Russian Native or bilingual proficiency
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Ukrainian Native or bilingual proficiency
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German Elementary proficiency
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Experience
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Life Chemicals
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Canada
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Chemical Manufacturing
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1 - 100 Employee
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Head of Physicochemical Lab
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Sep 2016 - Present
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Ecopharm
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Ukraine
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1 - 100 Employee
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Head of Bioorganic Chemistry Unit
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Nov 2015 - Sep 2016
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Pharis Biotec GmbH
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Germany
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Biotechnology Research
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1 - 100 Employee
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Research Fellow
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Aug 2014 - 2015
Participant of U-PEP (Ulm Peptide Pharmaceuticals) Peptide-based drug discovery and development. Participation in Hit Hidden Hiv Project (http://www.hithiddenhiv.org/en/) Participant of U-PEP (Ulm Peptide Pharmaceuticals) Peptide-based drug discovery and development. Participation in Hit Hidden Hiv Project (http://www.hithiddenhiv.org/en/)
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Arterium
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Pharmaceutical Manufacturing
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200 - 300 Employee
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Senior Analytical Chemist
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2013 - 2014
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University of Limerick
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Ireland
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Higher Education
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700 & Above Employee
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Postdoctoral Research Associate
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2012 - May 2013
I was involved in proteomics activities dedicated to development of new methods for short peptides identification using UPLC-QTOF-MS. Implemented strategies have involved both de-novo (pepnovo, PEAKS) and database dependent search (MASCOT, OMMSA, Protein Prospector (MSs-tag, MS-products)) fortified with additional bioinformational models, some of those were based on neural networks. My supplementary activity also was directed on investigation retention behaviors of low molecular weight… Show more I was involved in proteomics activities dedicated to development of new methods for short peptides identification using UPLC-QTOF-MS. Implemented strategies have involved both de-novo (pepnovo, PEAKS) and database dependent search (MASCOT, OMMSA, Protein Prospector (MSs-tag, MS-products)) fortified with additional bioinformational models, some of those were based on neural networks. My supplementary activity also was directed on investigation retention behaviors of low molecular weight compounds on reverse phase chromatography by using Waters UPLC system coupled with QTOF. Additionally I was a perticiapnt of FHI (Food for health Ireland) Research Center. Show less I was involved in proteomics activities dedicated to development of new methods for short peptides identification using UPLC-QTOF-MS. Implemented strategies have involved both de-novo (pepnovo, PEAKS) and database dependent search (MASCOT, OMMSA, Protein Prospector (MSs-tag, MS-products)) fortified with additional bioinformational models, some of those were based on neural networks. My supplementary activity also was directed on investigation retention behaviors of low molecular weight… Show more I was involved in proteomics activities dedicated to development of new methods for short peptides identification using UPLC-QTOF-MS. Implemented strategies have involved both de-novo (pepnovo, PEAKS) and database dependent search (MASCOT, OMMSA, Protein Prospector (MSs-tag, MS-products)) fortified with additional bioinformational models, some of those were based on neural networks. My supplementary activity also was directed on investigation retention behaviors of low molecular weight compounds on reverse phase chromatography by using Waters UPLC system coupled with QTOF. Additionally I was a perticiapnt of FHI (Food for health Ireland) Research Center. Show less
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Jr. research group leader/research fellow, Bio-medical research department
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Jan 2010 - Feb 2013
•Inhibitors modeling (according to enzymes structure knowledge) with molecular docking (AutoDock4.2) •Antiviral drug discovery (influenza H1N1) •Lipopepide based drug discovery (Development of nanodrugs concept for protease inhibitors design). •Peptide and peptidomimetic synthesis. (Chemical and enzymatic). •Analysis and purification of compounds (peptidomimetics, peptides and proteins) by HPLC, FPLC. •Structure elucidation of low molecular wight compounds with 1D H-NMR, LC/MS… Show more •Inhibitors modeling (according to enzymes structure knowledge) with molecular docking (AutoDock4.2) •Antiviral drug discovery (influenza H1N1) •Lipopepide based drug discovery (Development of nanodrugs concept for protease inhibitors design). •Peptide and peptidomimetic synthesis. (Chemical and enzymatic). •Analysis and purification of compounds (peptidomimetics, peptides and proteins) by HPLC, FPLC. •Structure elucidation of low molecular wight compounds with 1D H-NMR, LC/MS, and LDI MS. •Proteomic methods development for protein structure features determination and investigation of enzyme-ligand (inhibitor) complexes by means of Matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS). •Commercial application of MALDI TOF MS. •Enzyme kinetics (Steady state)
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Jr. research fellow
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2007 - 2011
Protein Chemistry Department
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Research engeneer
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2003 - 2007
Department of Protein Chemistry
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HelmholtzZentrum München
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Germany
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Veterinary
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1 - 100 Employee
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Joit Ukrainian-German project participant
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2010 - 2010
Institute of bioinformatics and systems biology (IBIS), Chemoinformatics group Institute of bioinformatics and systems biology (IBIS), Chemoinformatics group
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Public Institution
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Norway
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Center of immunobiological drugs. Public Institution
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2009 - 2009
• Analytical laboratory arrangement and management. • Vaccines characterization by SEC, HPLC. • Novel vaccine characterization. • Analytical laboratory arrangement and management. • Vaccines characterization by SEC, HPLC. • Novel vaccine characterization.
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Uppsala University
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Sweden
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Higher Education
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700 & Above Employee
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Visby programme participant
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2006 - 2006
Proteochemometric group, Department of Pharmaceutical Biosciences Proteochemometric group, Department of Pharmaceutical Biosciences
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Specific purpose contract
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2006 - 2006
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Education
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Institute of Bioorganic Chemistry and Petrochemistry (BPCI) NAS of Ukraine
Doctor of Philosophy (PhD), Bioorganic chemistry -
Kyiv National Taras Shevchenko University
Master's degree, Organic Chemistry