Alexandre Chapeaux

Senior Director, Downstream Process at C16 Biosciences
  • Claim this Profile
Online Presence
Contact Information
Location
New York, New York, United States, US

Topline Score

Bio

Generated by
Topline AI

0

/5.0
/ Based on 0 ratings
  • (0)
  • (0)
  • (0)
  • (0)
  • (0)

Filter reviews by:

No reviews to display There are currently no reviews available.

0

/5.0
/ Based on 0 ratings
  • (0)
  • (0)
  • (0)
  • (0)
  • (0)

Filter reviews by:

No reviews to display There are currently no reviews available.
You need to have a working account to view this content. Click here to join now

Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Director, Downstream Process
      • Mar 2022 - Present

      New York City Metropolitan Area

    • Director, Downstream Process
      • Jul 2020 - Apr 2022

    • United Kingdom
    • Retail Groceries
    • Director Process
      • Aug 2018 - Apr 2020

      I oversee the entire process, sample generation, and manufacturing aspects of the company. I manage a team of 8 people. My team works to optimize yeast fermentation and functional protein purification to meet food product specs. We make samples at CROs to provide to potential clients to create demand and sales, and to prove the scalability of our process. We work with CMOs to tech transfer our process at scale to manufacture our products. I am responsible for techno-economic modeling,… Show more I oversee the entire process, sample generation, and manufacturing aspects of the company. I manage a team of 8 people. My team works to optimize yeast fermentation and functional protein purification to meet food product specs. We make samples at CROs to provide to potential clients to create demand and sales, and to prove the scalability of our process. We work with CMOs to tech transfer our process at scale to manufacture our products. I am responsible for techno-economic modeling, strategic planning, budgeting, and timely execution of all the research, engineering, and scale up projects. Show less

    • Georgia
    • IT Services and IT Consulting
    • Process Development Manager
      • Sep 2017 - Aug 2018

      San Francisco Bay Area I manage the process development and optimization of protein isolate purification. My team of researchers work to maintain protein functionality and purity during purification. I am responsible for the day to day operations of the process laboratory, help plan runs in the pilot plant, manage some tech transfer activities, and lead the design of a commercial plant. Key Achievements: Build, optimize and run Protein Separation Pilot Plant • Helped build and commission the protein… Show more I manage the process development and optimization of protein isolate purification. My team of researchers work to maintain protein functionality and purity during purification. I am responsible for the day to day operations of the process laboratory, help plan runs in the pilot plant, manage some tech transfer activities, and lead the design of a commercial plant. Key Achievements: Build, optimize and run Protein Separation Pilot Plant • Helped build and commission the protein pilot plant under time with small budget • Run successful pilot sized process development campaigns to optimize process • Run successful pilot production runs for internal product development and samples • Manage safety, scheduling, and ordering for the Pilot Plant • Developed a micro prevention and sampling plan to create consistent and safe isolates, adhere to cGMP. Develop a robust lab-scale protein process development • Installed, commissioned and tested lab UF and FLPC • Build tech transfer of data and protocols for new protein candidates, work to correlate assays with process data • Help develop analytical assays and procedures to characterize our materials • Design systems for the maintaining of isolate inventory, isolate data, isolate functionality • Develop functionality assays and data to help understand differences in isolates • Work to develop better communication and understanding of the various assays that other teams • Manage a team of researchers, mentoring junior staff, and overseeing summer interns Transfer our process to CMOs and manage relationships • Transfer lab processes, functionality processes, and pilot processes to CMO • Develop relationship with two other CMOs Design large scale protein manufacturing plant • Lead the team to design a commercial protein plant • Coordinate other technical leaders to provide data to contract engineer firm • Oversee the process to create FEL-1 and FEL-2 reports • Communicate cost and timelines to leadership. Show less

    • United States
    • Senior Process Engineer
      • Jul 2016 - Sep 2017

      San Francisco Bay Area

    • United States
    • Chemical Manufacturing
    • 1 - 100 Employee
    • Lead Chemical Engineer/Safety Officer
      • Feb 2013 - Jun 2016

      New Haven, CT My overall responsibilities are scale–up process optimization, green engineering design, permitting and techo-economic aspects of all the processes developed in the company. I oversee the layout and building of our laboratory and lab-pilot facility. I perform the economic and process safety analysis for the processes. I have key input on the business development, process decisions, and the production schedule. Key Achievements: Managed Development, Design, and Economic Viability… Show more My overall responsibilities are scale–up process optimization, green engineering design, permitting and techo-economic aspects of all the processes developed in the company. I oversee the layout and building of our laboratory and lab-pilot facility. I perform the economic and process safety analysis for the processes. I have key input on the business development, process decisions, and the production schedule. Key Achievements: Managed Development, Design, and Economic Viability of Demonstration-scale Production Facility •Lead scale–up process optimization, green engineering design, permitting and techno-economic aspects •Serve key role in business development, process decisions, and the production schedule •Hold deep understanding of core reaction technologies, intensified core reactions, and innovative reactor design •Build lab-pilot scale reactor systems to simulate large scale production in a continuous process •Designed whole process for the demonstration scale for engineering partnership •Develop supporting infrastructure and separation unit operations •Analyzed equipment, consumables, and infrastructure costs for the plant •Developed overall long term financial model for demonstration plant and full scale plant Safety Officer Responsibilities •Oversee economic and process safety analysis for the processes •Foster safety hazards mitigations for all processes and reactions in the laboratory and lab-pilot plant •Develop EHS manual and Standard Operating Procedures for the company with hands-on training •Supervise overall facility safety equipment inspections Show less

    • Research Engineer/Project Lead
      • Jul 2009 - Feb 2013

      Golden, CO Lead/Manage Industrial Project Researching Conversion of Ligno-cellulosic Biomass to Drop-in Fuels • Worked with the client to develop a commercially relevant process, setting targets • Designed experimental plan of bench-scale and pilot-scale experiments to meet goals and deadlines • Managed a team of 8-10 engineers and technicians Develop Processes and Procedures for Algal Biomass Extraction and Conversion to Biofuels • Managed and performed the enzymatic hydrolysis and… Show more Lead/Manage Industrial Project Researching Conversion of Ligno-cellulosic Biomass to Drop-in Fuels • Worked with the client to develop a commercially relevant process, setting targets • Designed experimental plan of bench-scale and pilot-scale experiments to meet goals and deadlines • Managed a team of 8-10 engineers and technicians Develop Processes and Procedures for Algal Biomass Extraction and Conversion to Biofuels • Managed and performed the enzymatic hydrolysis and fermentation experiments to consider alternative uses for the carbohydrate and protein portions of the Improve Process Configuration for the Production of Fuel Ethanol to Meet DOE Targets • Developed an innovative process configuration for ethanol production, and performed enzymatic hydrolyses and microbial fermentations on the bench scale. • Calculated mass balance and mass closure for the whole process Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Post Doctoral Researcher
      • May 2009 - Jun 2009

      Study of Energy Related Binary and Ternary Systems involving Ionic Liquids • Vapor-liquid measurement of mixtures of gases (CO2, O2, CH4…) with Ionic Liquids • Extraction of compounds from Ionic Liquids using high-pressure CO2 • Synthesis of Ionic Liquids

    • Graduate Research Assistant
      • Aug 2004 - May 2009

      Study of Energy Related Binary and Ternary Systems involving Ionic Liquids • Separation of alcohols and water using Ionic Liquids • Liquid-liquid equilibrium measurements with Ionic Liquids • Vapor-liquid measurement of mixtures of gases (CO2, O2, CH4…) with Ionic Liquids • Extraction of compounds from Ionic Liquids using high-pressure CO2 • Measurements of enthalpies of mixing of ionic liquid and alcohol mixtures • Measurement of long-term decompositions of Ionic Liquids •… Show more Study of Energy Related Binary and Ternary Systems involving Ionic Liquids • Separation of alcohols and water using Ionic Liquids • Liquid-liquid equilibrium measurements with Ionic Liquids • Vapor-liquid measurement of mixtures of gases (CO2, O2, CH4…) with Ionic Liquids • Extraction of compounds from Ionic Liquids using high-pressure CO2 • Measurements of enthalpies of mixing of ionic liquid and alcohol mixtures • Measurement of long-term decompositions of Ionic Liquids • Synthesis of Ionic Liquids

    • United States
    • Research Services
    • 700 & Above Employee
    • Research Aid
      • May 2006 - Aug 2006

      Liquid-Liquid Equilibrium Study of the Separation of Ethanol and Water using Ionic Liquids * Designed and executed experimental plan. * Set-up of a laboratory to make and handle ionic liquids * Synthesized and purified ionic liquids * Developed methods for ionic liquid measurement on HPLC * Mentored undergraduates and high-school students

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Jan 2001 - Apr 2004

      • Study of the effects of inhibitors on the growth of Candida used in the production of xylitol. • Design a process to use luminescent bacteria in the treatment of wastewater • Set-up, testing, and trouble shooting of High Performance Liquid Chromatograph (HPLC) for measurement of sugars concentrations • Examined the stability and viability of the yeast Pichia Pastoris while immobilized in calcium alginate beads with dilution cell plating and respirometry

Education

  • University of Notre Dame
    Ph.D., Chemical Engineering
    2004 - 2009
  • University of Notre Dame
    M.S., Chemical Engineering
    2004 - 2008
  • Syracuse University
    B.S., Chemical Engineering
    2000 - 2004

Community

You need to have a working account to view this content. Click here to join now