Alexandra Surcel
Science & Engineering Policy Analyst at National Science Board (NSB)- Claim this Profile
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English Native or bilingual proficiency
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Romanian Professional working proficiency
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Bio
JOSEPH DEBES
Works until it's DONE RIGHT/ Detail oriented
Susan MacDonald
Alexandra is an exceptional person. She is brilliant, but acts normal. She is a true pleasure to know. Susan M. MacDonald, M.D.
JOSEPH DEBES
Works until it's DONE RIGHT/ Detail oriented
Susan MacDonald
Alexandra is an exceptional person. She is brilliant, but acts normal. She is a true pleasure to know. Susan M. MacDonald, M.D.
JOSEPH DEBES
Works until it's DONE RIGHT/ Detail oriented
Susan MacDonald
Alexandra is an exceptional person. She is brilliant, but acts normal. She is a true pleasure to know. Susan M. MacDonald, M.D.
JOSEPH DEBES
Works until it's DONE RIGHT/ Detail oriented
Susan MacDonald
Alexandra is an exceptional person. She is brilliant, but acts normal. She is a true pleasure to know. Susan M. MacDonald, M.D.
Experience
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National Science Board (NSB)
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United States
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Government Administration
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1 - 100 Employee
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Science & Engineering Policy Analyst
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Aug 2022 - Present
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AAAS
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United States
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Non-profit Organizations
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400 - 500 Employee
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AAAS Science and Technology Policy Fellow, Executive Branch (@NSF, @NSF_NSB)
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Sep 2020 - Dec 2022
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Johns Hopkins School of Medicine
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United States
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Hospitals and Health Care
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700 & Above Employee
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Faculty Research Associate
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Nov 2014 - Sep 2020
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Postdoctoral Fellow
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Nov 2007 - Nov 2014
Cell mechanics form the bedrock of a wide array of biological processes in healthy cells. In conjunction with biochemical signals, mechanical signals direct cell division, cell migration, and cell death. Changes in these parameters lead to vastly different cell and tissue outcomes, including cancer, pathogen invasion, hypertension, and degeneration, annually affecting hundreds of millions of people worldwide. I applied my chemical engineering and biological expertise in a highly… Show more Cell mechanics form the bedrock of a wide array of biological processes in healthy cells. In conjunction with biochemical signals, mechanical signals direct cell division, cell migration, and cell death. Changes in these parameters lead to vastly different cell and tissue outcomes, including cancer, pathogen invasion, hypertension, and degeneration, annually affecting hundreds of millions of people worldwide. I applied my chemical engineering and biological expertise in a highly translational program, to uncover novel compounds capable of dissecting cytokinesis pathways, shedding light on the mechanics of a variety of cancers (in particular pancreatic cancer) or impinging upon the cell viability of pathogenic amoebas. These project areas hold tremendous potential in the development of new, mechanics based therapeutics.
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Penn State University
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United States
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Higher Education
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700 & Above Employee
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Graduate student
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2000 - 2007
I was interested in discerning the structure of the cohesin complex involved in maintaining sister chromatid cohesin. To that end, I employed minichromosome affinity purification coupled with electron microscopy to isolated and analyze cohesin complexes attached to replicated minichromosomes. Additionally I performed a complete phylogenetic analysis on SMC proteins - a subset of which are found in cohesin and condensin complexes. I was interested in discerning the structure of the cohesin complex involved in maintaining sister chromatid cohesin. To that end, I employed minichromosome affinity purification coupled with electron microscopy to isolated and analyze cohesin complexes attached to replicated minichromosomes. Additionally I performed a complete phylogenetic analysis on SMC proteins - a subset of which are found in cohesin and condensin complexes.
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Johns Hopkins University
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United States
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Hospitals and Health Care
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1 - 100 Employee
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Undergraduate Student
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1995 - 2000
B.A. in Chemistry B.A. in Public Health B.A. in Chemistry B.A. in Public Health
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Education
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Penn State University
PhD, Cell and Developmental Biology -
The Johns Hopkins University
BA, Chemistry, Public Health