Alexandra Danilova
Director of Science and Innovation at Pharmforward- Claim this Profile
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Русский Native or bilingual proficiency
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Английский Full professional proficiency
Topline Score
Bio
Credentials
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Продвинутый Power BI
LabaMay, 2021- Nov, 2024 -
Convolutional Neural Networks
CourseraJun, 2020- Nov, 2024 -
Бизнес-анализ
LabaMay, 2020- Nov, 2024 -
Fundamentals of Quantitative Modeling
CourseraDec, 2019- Nov, 2024 -
Improving Deep Neural Networks: Hyperparameter tuning, Regularization and Optimization
CourseraDec, 2019- Nov, 2024 -
Machine Learning
CourseraDec, 2019- Nov, 2024 -
Neural Networks and Deep Learning
CourseraDec, 2019- Nov, 2024 -
Structuring Machine Learning Projects
CourseraDec, 2019- Nov, 2024 -
Introduction to Genetics and Evolution
CourseraJan, 2013- Nov, 2024 -
Drugs and the Brain
CourseraDec, 2012- Nov, 2024 -
Bioelectricity: A Quantitative Approach
CourseraSep, 2012- Nov, 2024
Experience
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Pharmforward
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Russian Federation
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Director of Science and Innovation
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Dec 2021 - Present
Developed a plan for the strategic development of the future pharmaceutical plant, taking into account the latest industry trends
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Business Intelligence Analyst
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Jan 2019 - Dec 2021
1. Implemented Power BI analytics in the company's business processes2. Analyzed many drugs from various nosologies (oncology, diabetes mellitus, rheumatology, cardiology, orphan diseases): analysis of the mechanism of action and medical information, competitors, SWOT analysis, market analysis, sales forecast3. Developed a business model for the planned pharmaceutical plant (P&L, CashFlow, NPV, IRR). The project received the approval of the special economic zone
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InnovaPlus
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Saint Petersburg, Russian Federation
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Lead Researcher
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Mar 2018 - Dec 2018
1. Led 10 researchers in biotechnology, genetic engineering and cytology projects 2. Created and filed an application for Skolkovo Participant status, which received approval 1. Led 10 researchers in biotechnology, genetic engineering and cytology projects 2. Created and filed an application for Skolkovo Participant status, which received approval
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BIOCAD
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Russian Federation
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Pharmaceutical Manufacturing
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500 - 600 Employee
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R&D Scientist
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Oct 2017 - Dec 2017
1. Participated in adeno-associated viral vectors production bioprocess development. Introduced DoE platform to increase the development process efficiency 2. Developed E. coli fermentation process for plasmid DNA production 1. Participated in adeno-associated viral vectors production bioprocess development. Introduced DoE platform to increase the development process efficiency 2. Developed E. coli fermentation process for plasmid DNA production
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Pharm-Holding
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Russian Federation
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Head of fermentation laboratory
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Aug 2016 - Aug 2017
Laboratory Management:1. Conducted scientific research for approaches to the effective production of various recombinant proteins in E. coli. Fermentation processes were developed on Sartorius Biostat B with working volume 5 l and then scaled up to the 150 l bioreactor2. Organized screening studies of producer strains, media composition, cultivation conditions3. Formed a team. Paid great attention to professional development of staff4. The laboratory developed highly productive fermentation processes for producers of various therapeutic molecules (Fab, Fc-fusion protein, insulin and analogues) over the year under my leadershipProject Management:1. Developed the biotechnology project schedule from producer strain creation to preclinical studies2. Regularly reported on the project progress to the top management of the company Show less
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R&D Scientist
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Jul 2014 - Jul 2016
1. Participated in different stages of drug research and development, from molecular cloning to in vitro evaluation of biological activity2. Created a number of genetic constructs for the expression of recombinant proteins in both the cytoplasm and the periplasm of E. coli. Conducted screening studies of producer strains. The selected producer strains have been successfully used to produce recombinant therapeutic molecules.3. Conducted studies of the biological activity of a number of drugs using cell-based and biochemical methods. The results of the studies were included in the CTD Show less
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Pavlov Physiology Institute of the Russian Academy of Sciences
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Saint Petersburg
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Research Assistant
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Mar 2014 - Jun 2014
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Education
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Saint Petersburg State University
Master's degree, Neuroscience -
Saint Petersburg State University
Bachelor's degree, Genetics