Experience

New York Structural Biology Center

• United States
• Research Services
• 1 - 100 Employee

• Group Leader

  • Jan 2021 - Present

• Postdoctoral Fellow / Research Scientist

  • 2018 - Dec 2020

  Ruth L. Kirschstein Postdoctoral Fellow

• Postdoctoral Research Scientist

  • Aug 2016 - Dec 2020

  Tomography, sub-tomogram averaging, deep learning applications, and cell tomography hardware and software development towards automation, high throughput, and high resolution biological structure determination.



Florida State University

• United States
• Higher Education
• 700 & Above Employee

• Research Assistant

  • Aug 2011 - Jul 2016

  I work on developing and applying high-throughput and optimization methods to reliably solve macromolecular protein structures. I am currently studying the biologically available conformations of the COPII vesicle through molecular dynamics and normal modes simulations as a generic case for an optimization procedure. I am developing high throughput, easily accessible tomography reconstruction interfaces and software. I am also currently collaborating on solving a near-atomic model resolution… Show more I work on developing and applying high-throughput and optimization methods to reliably solve macromolecular protein structures. I am currently studying the biologically available conformations of the COPII vesicle through molecular dynamics and normal modes simulations as a generic case for an optimization procedure. I am developing high throughput, easily accessible tomography reconstruction interfaces and software. I am also currently collaborating on solving a near-atomic model resolution structure of a gene therapy virus capsid through frame-based weighting of a sample imaged using cryo-electron microscopy. I regularly interact with raw data from Cryo-electron Microscopy, Cryo-electron Tomography, X-Ray Crystallography, and Hydrogen-Deuterium Exchange Mass Spectrometry. Show less I work on developing and applying high-throughput and optimization methods to reliably solve macromolecular protein structures. I am currently studying the biologically available conformations of the COPII vesicle through molecular dynamics and normal modes simulations as a generic case for an optimization procedure. I am developing high throughput, easily accessible tomography reconstruction interfaces and software. I am also currently collaborating on solving a near-atomic model resolution… Show more I work on developing and applying high-throughput and optimization methods to reliably solve macromolecular protein structures. I am currently studying the biologically available conformations of the COPII vesicle through molecular dynamics and normal modes simulations as a generic case for an optimization procedure. I am developing high throughput, easily accessible tomography reconstruction interfaces and software. I am also currently collaborating on solving a near-atomic model resolution structure of a gene therapy virus capsid through frame-based weighting of a sample imaged using cryo-electron microscopy. I regularly interact with raw data from Cryo-electron Microscopy, Cryo-electron Tomography, X-Ray Crystallography, and Hydrogen-Deuterium Exchange Mass Spectrometry. Show less