Experience

Lions VisionGift

• Clinical Research Associate

  • Jul 2017 - Present

  Portland, Oregon



Adverum Biotechnologies, Inc.

• Senior Research Associate

  • May 2015 - Jul 2017

  San Francisco Bay Area Senior Research Associate on the Preclinical Development Team. Designed and executed in vivo experiments based on gene therapy for ocular and systemic diseases. Performed various ophthalmic imaging modalities in vivo to identify the efficacy and safety of adeno-associated viral vectors (AAV). Interpreted, organized, and presented data from experiments conducted internally and at CRO’s. Responsible for generating reliable and reproducible preclinical data for the following drug… Show more Senior Research Associate on the Preclinical Development Team. Designed and executed in vivo experiments based on gene therapy for ocular and systemic diseases. Performed various ophthalmic imaging modalities in vivo to identify the efficacy and safety of adeno-associated viral vectors (AAV). Interpreted, organized, and presented data from experiments conducted internally and at CRO’s. Responsible for generating reliable and reproducible preclinical data for the following drug programs: • Cone-specific AAV’s for color vision disorders (preclinical) • Directed evolution platform for wet age-related macular degeneration (preclinical) • X-linked Retinoschisis (XLRS) collaboration with Regeneron Pharmaceuticals (preclinical) • Next generation AAV serotype for alpha-1 antitrypsin (A1AT) deficiency and hereditary angioedema (HAE) Show less



Allergan

• Pharmaceutical Manufacturing
• 700 & Above Employee

• Professional

  • Jan 2010 - Apr 2015

  Orange County, California Area Professional Biologist on the Retina Disease Research Team. Key contributor in testing the angiostatic and anti-inflammatory efficacy of novel compounds in animal models of pathological neovascularization and vascular permeability (rabbit, rat, and mouse). Conceptualized and developed proprietary in vivo models of neovascularization and retinal vessel permeability in order to reliably assess proof of concept around new targets and platforms. Helped design and implemented protocols to… Show more Professional Biologist on the Retina Disease Research Team. Key contributor in testing the angiostatic and anti-inflammatory efficacy of novel compounds in animal models of pathological neovascularization and vascular permeability (rabbit, rat, and mouse). Conceptualized and developed proprietary in vivo models of neovascularization and retinal vessel permeability in order to reliably assess proof of concept around new targets and platforms. Helped design and implemented protocols to differentiate multiple formats of a novel biologic platform. Designed and optimized immunohistochemistry protocols for evaluation of novel endpoints in proprietary models of vascular pathology. Responsible for generating reliable and reproducible preclinical data for the following drug programs: • Abicipar pegol (anti vascular endothelial growth factor, Phase 3) • Early discovery DARPin projects (preclinical) • Angiostatic Anticalin therapeutics (preclinical) • Multi-kinase inhibitor platforms (preclinical Show less