Albert Lee
Golden Touch Genomic Data Alchemist at Guardant Health- Claim this Profile
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Bio
Experience
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Guardant Health
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United States
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Biotechnology Research
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700 & Above Employee
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Golden Touch Genomic Data Alchemist
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Apr 2022 - Present
Redwood City, California, United States
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Senior Bioinformatics Scientist
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Sep 2020 - Apr 2022
Redwood City, California, United States
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Myriad Genetics
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United States
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Biotechnology Research
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700 & Above Employee
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Bioinformatics Scientist II
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Jul 2018 - Sep 2020
United States ● Led the bioinformatics updates and performed the analytical validation of the new assay called Prequel® AMPLIFY, which resulted in 2.3x amplification of fetal fraction. ● Developed and deployed the fetal sex prediction model using the Bayesian hierarchical classifier, enhancing the performance of an existing algorithm. The model processes 110,000+ clinical samples per year. ● Communicated complex results to non-technical collaborators and provided the data-driven recommendation and… Show more ● Led the bioinformatics updates and performed the analytical validation of the new assay called Prequel® AMPLIFY, which resulted in 2.3x amplification of fetal fraction. ● Developed and deployed the fetal sex prediction model using the Bayesian hierarchical classifier, enhancing the performance of an existing algorithm. The model processes 110,000+ clinical samples per year. ● Communicated complex results to non-technical collaborators and provided the data-driven recommendation and direction for business-critical decisions. Show less
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Counsyl
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United States
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Biotechnology Research
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1 - 100 Employee
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Bioinformatics Scientist I
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Jan 2018 - Jul 2018
● Led the R&D project from investigation to development to validation and launch, resulting in the product feature "Expanded Aneuploidy Analysis'' of its non-invasive prenatal testing (NIPT). ● Performed computational science analysis, project management/execution with high quality and rigorous SWE best practices for multiple projects, enhancing the performance. ● Applied the advanced Bayesian statistical inference using the state-of-the-art Markov Chain Monte Carlo (MCMC) algorithm and… Show more ● Led the R&D project from investigation to development to validation and launch, resulting in the product feature "Expanded Aneuploidy Analysis'' of its non-invasive prenatal testing (NIPT). ● Performed computational science analysis, project management/execution with high quality and rigorous SWE best practices for multiple projects, enhancing the performance. ● Applied the advanced Bayesian statistical inference using the state-of-the-art Markov Chain Monte Carlo (MCMC) algorithm and the large scale machine learning; detailed analytic performance evaluation and operational considerations. ● Worked with a large codebase, performed thorough code reviews, wrote high quality technical documentations, and mentored other software engineers and scientists. Show less
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Graduate Student Researcher
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Sep 2011 - Dec 2017
New York Advisor: Prof. Raul Rabadan ● Designed and built the statistical framework and software based on Bayesian multilevel modeling technique to analyze complex(14000+ genes/3 tissues/5 time points) RNA sequencing data by combining tools such as R, Shiny (interactive visualization), Stan (probabilistic programming), and SGE (parallelization). ● Collaborated with researchers from Boston University, U.S. Army Medical Research Institute of Infectious Diseases(USAMRIID), and Centers for… Show more Advisor: Prof. Raul Rabadan ● Designed and built the statistical framework and software based on Bayesian multilevel modeling technique to analyze complex(14000+ genes/3 tissues/5 time points) RNA sequencing data by combining tools such as R, Shiny (interactive visualization), Stan (probabilistic programming), and SGE (parallelization). ● Collaborated with researchers from Boston University, U.S. Army Medical Research Institute of Infectious Diseases(USAMRIID), and Centers for Disease Control and Prevention(CDC) on characterizing genome and transcriptome of Egyptian Fruit Bat. Show less
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Supervisor; Physics Tutor
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Sep 2008 - Jun 2010
● Tutored university physics course to undergraduate students; Topics include Mechanics, Electricity, Waves, & Magentism. ● Held the bi-weekly department meeting with tutors discussing various issues related to tutoring and the AAP program.
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Peer Learning Facilitator
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Jul 2009 - Sep 2009
● Tutored Calculus to 60 incoming university freshman / transfer students ● Led daily recitations / discussions, EXCEL workshops, and evening drop-in tutoring
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Education
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Columbia University in the City of New York
Doctor of Philosophy (Ph.D.), Biomedical informatics / Systems biology -
Columbia University in the City of New York
MA, Biomedical Informatics -
UCLA
B.S., Molecular, Cell, Developmental Biology