Experience

Medchemica Ltd

• United Kingdom
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Managing Director

  • Aug 2012 - Present

  Cheshire Founding member of the company built on innovative thinking around Matched Molecular Pair Analysis Business Development and contracting with new clients Strategic business planning and budgeting R&D Project Management Medicinal Chemistry Design work and consultancy Creative solution generation for clients Recruitment



Society of Chemical Industry

• United States
• 1 - 100 Employee

• Member of Fine Chemicals Group

  • Apr 2013 - Present

  Conception, development and delivery of conferences and courses for professional scientists. Currently on the organising committee for 'Designing Safer Medicines: What works and what doesn’t' - October 2014



AstraZeneca

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Team Leader Medicinal Chemistry

  • Jul 2008 - Oct 2012

  CVGI Innovative Medicines Unit Diabetes and Obesity small molecule discovery Line manager of a team of 6 people Work in CVGI has focused on:- Compound design Data Analysis (e.g. matched pair analysis) Strategic thinking and planning in projects CNS penetration targets - receptors and enzymes PET ligand selection and synthesis Inverse agonist… Show more Diabetes and Obesity small molecule discovery Line manager of a team of 6 people Work in CVGI has focused on:- Compound design Data Analysis (e.g. matched pair analysis) Strategic thinking and planning in projects CNS penetration targets - receptors and enzymes PET ligand selection and synthesis Inverse agonist design Library design and strategic building block synthesis Competitive intelligence Creative problem solving Training and development through a strength based culture Improving Meeting Culture delivery

• Medicinal Chemistry: Team Leader

  • Aug 1999 - Jun 2008

  Alderley Park, Cheshire Medicinal chemistry in Inflammation research area. Team Leader of seven people. Coaching and development of a new starting team leader / medicinal chemist Conception and development of a course to increase performance of chemists at the bench through time management / organisation, team working on route design. Delivery of candidate drugs compound series against protease and GPCR targets for pre-clincal work against Rheumatoid and Osteo - arthritis. Specialities in high… Show more Medicinal chemistry in Inflammation research area. Team Leader of seven people. Coaching and development of a new starting team leader / medicinal chemist Conception and development of a course to increase performance of chemists at the bench through time management / organisation, team working on route design. Delivery of candidate drugs compound series against protease and GPCR targets for pre-clincal work against Rheumatoid and Osteo - arthritis. Specialities in high through-put screening work-up to select active series through clustering and scoring mechanisms to eliminate false positives and identify false negatives. Project leadership in early stage projects. Medicinal Chemist and team leader on Oncology projects Targets for hormonally driven tumours and receptor tyrosine kinase inhibitors. Working group to establish lead generation specialised capability

• Member of Fine Chemicals Group

  • 2004 - Jun 2010

  Young Chemists Panel (YCP) - Conception, development and delivery of conferences and courses for professional scientists. Led and delivered 'Discovery Synthetic Chemistry' 2006, 2008 and 2010. Course tutor on 'Chemistry for Non-chemists'. Established the YCP SCI group on LinkedIn.



Harvard University

• United States
• Higher Education
• 1 - 100 Employee

• Research Associate

  • Jan 1998 - Jun 1999

  Discovery of a new highly selective catalyst for asymmetric hetero-Diels Alder reaction working with Professor Eric Jacobsen. This ground breaking work for the group produced a grant proposal (and patent) to secure million dollar funding for further work, and further significant discoveries and natural product syntheses.


University of Nottingham
• United Kingdom
• Research Services
• 700 & Above Employee
• Student

  • 1994 - 1998


Salcare

• United Kingdom
• Individual and Family Services
• 1 - 100 Employee

• Cafe Manager

  • Jul 1992 - Sep 1992

  Heanor, Derbyshire, UK I returned to the cafe for another summer and for the second time returned it to profit. Along with this challenge I managed volunteers and disabled part time workers.

• Cafe Manager

  • Jul 1991 - Sep 1991

  Heanor, Derbyshire, UK Salcare is a charity recycling used goods into the hands of needy local people. I took over managing the cafe for summer work and returned it to working a small profit by focusing on customer needs and rigorous control of costs.