Aistė Jekabsone
Chief Executive Officer at EXOLITUS- Claim this Profile
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Bio
Experience
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EXOLITUS
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Lithuania
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Research Services
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1 - 100 Employee
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Chief Executive Officer
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Feb 2020 - Present
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Institute of Parmaceutical Technologies, LSMU
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Kaunas, Lithuania
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Head of Laboratory of Pharmaceutical Sciences
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Nov 2018 - Present
Design of more efficient models for drug testing, development of local/targeted delivery system, exosome application, bioactive hydrogel material investigation and application, nutraceutical and functional food solutions. On-going projects: 2018 – 2020 Functional food design project „Promotion of Birštono mineraliniai vandenys UAB investment towards R&D activities for development of innovative products“ No. J05-LVPA-K-01-0220, R&D Grant measure „Intelektas. Bendri mokslo ir verslo projektai“, Lithuanian Business Support Agency. Responsibility – in vitro research planning and coordination. 2018 – 2020 Functional food design project „Promotion of Akvavita UAB investment towards R&D activities for development of innovative products in the refreshing drink industry“ J05-LVPA-K-01-024, R&D Grant measure „Intelektas. Bendri mokslo ir verslo projektai“,Lithuanian Business Support Agency. Responsibility – in vitro research planning and coordination. 2017-2019 M-Era.Net project "Engineering and functionalization of delivery system with Pelargonium sidoides biologically active substance on inflamed periodontal surface area", PELARGODONT, S-M-ERA.NET-17-2. Cosortium of 7 international partners, leaded by LSMU, main coordinator - prof. Nijole Savickienė, second coordinator - Aiste Jekabsone. 2017-2021 "Exosome application for targeted drug delivery", EXOTARGET, 01.2.2-LMT-K-718-01-0036, supported by European Regional Funds under Global grant measure "Research projects implemented by world-class researcher groups". Project leader - Aiste Jekabsone. Number of national projects led in the past - 7, three of them R&D, other - scientific research projects. Participated in 9 projects leaded by other scientists, 3 of them - under international mobility schemes.
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Sr. Scientist
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Apr 2018 - Present
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Lithuanian University of Health Sciences, Neuroscience Institute
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Kaunas, Lithuania
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Scientific Researcher
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Sep 2002 - Present
Currently focus on the development of more efficient in vitro and ex vivo models for neurodegenerative pathology investigation and drug testing as well as targeted delivery device design. On-going projects: 2017-(2019) M-Era.Net project "Engineering and functionalization of delivery system with Pelargonium sidoides biologically active substance on inflamed periodontal surface area", PELARGODONT, S-M-ERA.NET-17-2. Cosortium of 7 international partners, leaded by Lithuanian University of Health Sciences, main coordinator - prof. Nijole Savickienė, second coordinator - Aiste Jekabsone. 2017-(2021) "Exosome application for targeted drug delivery", EXOTARGET, 01.2.2-LMT-K-718-01-0036, supported by European Social Fund under the Global grant measure "Research projects implemented by world-class researcher groups". Project leader - Aiste Jekabsone. Number of national projects leaded in the past - 7, two of the R&D. Participated in 3 projects leaded by other scientists.
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Lithuanian University of Health Sciences
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Lithuania
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Higher Education
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400 - 500 Employee
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Lecturer
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Sep 2015 - Jun 2016
Giving Biochemistry course for 1st grade 2nd year students and practical laboratory work. Giving Biochemistry course for 1st grade 2nd year students and practical laboratory work.
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Šv. Jono vaikai, Vš. Į.
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Apatiškių km., Trakų raj
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Social Worker
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Aug 2013 - Jun 2015
For a couple of years, our family lived together with the children of a family-model orphanage in the countryside. This was not only a work experience, this was life experience. For a couple of years, our family lived together with the children of a family-model orphanage in the countryside. This was not only a work experience, this was life experience.
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Cambridge University Department of Biochemistry, Professor Guy C. Brown group
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Cambridge, United Kingdom
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Postdoctoral Research Associate, Marie-Curie fellow
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Nov 2004 - Nov 2006
Investigation of nitric oxide signaling pathways in stroke models and the role of microglial cells in Alzheimer‘s disease. Primary neuronal-glial and pure microglial cell culture, fluorescent microscopy, cell viability according to Hoechst33342 and propidium iodide nuclear staining and MTT assay, neuronal membrane potential evaluation, spectrometry, fluorometry, ELISA. Investigation of nitric oxide signaling pathways in stroke models and the role of microglial cells in Alzheimer‘s disease. Primary neuronal-glial and pure microglial cell culture, fluorescent microscopy, cell viability according to Hoechst33342 and propidium iodide nuclear staining and MTT assay, neuronal membrane potential evaluation, spectrometry, fluorometry, ELISA.
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Junior scientific researcher
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Sep 1997 - Sep 2002
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Cambridge University, Department of Biochemistry
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Cambridge, United Kingdom
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Internship, supported by FEBS fellowship
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May 2000 - Jul 2000
Determination of cytochrome c release from mitochondrial intermembrane space to citoplasm of cardiomyocytes by Western blotting. Determination of cytochrome c release from mitochondrial intermembrane space to citoplasm of cardiomyocytes by Western blotting.
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The Martin Luther University of Halle-Wittenberg, Neurology Clinic, Dr. F.N. Gellerich group
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Halle-an-der-Saale, Germany
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Internship, supported by German Academic Exchange Service
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May 1998 - Aug 1998
Examination of mitochondrial functions in the cases of muscular neuropathies by measuring mitochondrial respiration in skinned muscle and cardiac fibers and determining activity of mitochondrial respiratory chain enzymes. Examination of mitochondrial functions in the cases of muscular neuropathies by measuring mitochondrial respiration in skinned muscle and cardiac fibers and determining activity of mitochondrial respiratory chain enzymes.
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Education
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Lithuanian University of Health Sciences
Doctor of Philosophy - PhD, Biomedical/Medical Engineering -
Vytauto Didžiojo universitetas
Master of Science - MS, Molecular Biology and Biotechnology -
Vytauto Didžiojo universitetas
Bachelor of Science - BS, Biology/Biological Sciences, General -
Kaunas 37th secondary school
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Kaunas Art School of Antanas Martinaitis
Art/Art Studies, General