Aistė Jekabsone

Chief Executive Officer at EXOLITUS
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Contact Information
us****@****om
(386) 825-5501
Location
LT

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Experience

    • Lithuania
    • Research Services
    • 1 - 100 Employee
    • Chief Executive Officer
      • Feb 2020 - Present

    • Head of Laboratory of Pharmaceutical Sciences
      • Nov 2018 - Present

      Design of more efficient models for drug testing, development of local/targeted delivery system, exosome application, bioactive hydrogel material investigation and application, nutraceutical and functional food solutions. On-going projects: 2018 – 2020 Functional food design project „Promotion of Birštono mineraliniai vandenys UAB investment towards R&D activities for development of innovative products“ No. J05-LVPA-K-01-0220, R&D Grant measure „Intelektas. Bendri mokslo ir verslo projektai“, Lithuanian Business Support Agency. Responsibility – in vitro research planning and coordination. 2018 – 2020 Functional food design project „Promotion of Akvavita UAB investment towards R&D activities for development of innovative products in the refreshing drink industry“ J05-LVPA-K-01-024, R&D Grant measure „Intelektas. Bendri mokslo ir verslo projektai“,Lithuanian Business Support Agency. Responsibility – in vitro research planning and coordination. 2017-2019 M-Era.Net project "Engineering and functionalization of delivery system with Pelargonium sidoides biologically active substance on inflamed periodontal surface area", PELARGODONT, S-M-ERA.NET-17-2. Cosortium of 7 international partners, leaded by LSMU, main coordinator - prof. Nijole Savickienė, second coordinator - Aiste Jekabsone. 2017-2021 "Exosome application for targeted drug delivery", EXOTARGET, 01.2.2-LMT-K-718-01-0036, supported by European Regional Funds under Global grant measure "Research projects implemented by world-class researcher groups". Project leader - Aiste Jekabsone. Number of national projects led in the past - 7, three of them R&D, other - scientific research projects. Participated in 9 projects leaded by other scientists, 3 of them - under international mobility schemes.

    • Scientific Researcher
      • Sep 2002 - Present

      Currently focus on the development of more efficient in vitro and ex vivo models for neurodegenerative pathology investigation and drug testing as well as targeted delivery device design. On-going projects: 2017-(2019) M-Era.Net project "Engineering and functionalization of delivery system with Pelargonium sidoides biologically active substance on inflamed periodontal surface area", PELARGODONT, S-M-ERA.NET-17-2. Cosortium of 7 international partners, leaded by Lithuanian University of Health Sciences, main coordinator - prof. Nijole Savickienė, second coordinator - Aiste Jekabsone. 2017-(2021) "Exosome application for targeted drug delivery", EXOTARGET, 01.2.2-LMT-K-718-01-0036, supported by European Social Fund under the Global grant measure "Research projects implemented by world-class researcher groups". Project leader - Aiste Jekabsone. Number of national projects leaded in the past - 7, two of the R&D. Participated in 3 projects leaded by other scientists.

    • Lithuania
    • Higher Education
    • 400 - 500 Employee
    • Lecturer
      • Sep 2015 - Jun 2016

      Giving Biochemistry course for 1st grade 2nd year students and practical laboratory work. Giving Biochemistry course for 1st grade 2nd year students and practical laboratory work.

  • Šv. Jono vaikai, Vš. Į.
    • Apatiškių km., Trakų raj
    • Social Worker
      • Aug 2013 - Jun 2015

      For a couple of years, our family lived together with the children of a family-model orphanage in the countryside. This was not only a work experience, this was life experience. For a couple of years, our family lived together with the children of a family-model orphanage in the countryside. This was not only a work experience, this was life experience.

    • Postdoctoral Research Associate, Marie-Curie fellow
      • Nov 2004 - Nov 2006

      Investigation of nitric oxide signaling pathways in stroke models and the role of microglial cells in Alzheimer‘s disease. Primary neuronal-glial and pure microglial cell culture, fluorescent microscopy, cell viability according to Hoechst33342 and propidium iodide nuclear staining and MTT assay, neuronal membrane potential evaluation, spectrometry, fluorometry, ELISA. Investigation of nitric oxide signaling pathways in stroke models and the role of microglial cells in Alzheimer‘s disease. Primary neuronal-glial and pure microglial cell culture, fluorescent microscopy, cell viability according to Hoechst33342 and propidium iodide nuclear staining and MTT assay, neuronal membrane potential evaluation, spectrometry, fluorometry, ELISA.

    • Internship, supported by FEBS fellowship
      • May 2000 - Jul 2000

      Determination of cytochrome c release from mitochondrial intermembrane space to citoplasm of cardiomyocytes by Western blotting. Determination of cytochrome c release from mitochondrial intermembrane space to citoplasm of cardiomyocytes by Western blotting.

    • Internship, supported by German Academic Exchange Service
      • May 1998 - Aug 1998

      Examination of mitochondrial functions in the cases of muscular neuropathies by measuring mitochondrial respiration in skinned muscle and cardiac fibers and determining activity of mitochondrial respiratory chain enzymes. Examination of mitochondrial functions in the cases of muscular neuropathies by measuring mitochondrial respiration in skinned muscle and cardiac fibers and determining activity of mitochondrial respiratory chain enzymes.

Education

  • Lithuanian University of Health Sciences
    Doctor of Philosophy - PhD, Biomedical/Medical Engineering
    1998 - 2002
  • Vytauto Didžiojo universitetas
    Master of Science - MS, Molecular Biology and Biotechnology
    1995 - 1997
  • Vytauto Didžiojo universitetas
    Bachelor of Science - BS, Biology/Biological Sciences, General
    1991 - 1995
  • Kaunas 37th secondary school
    1980 - 1991
  • Kaunas Art School of Antanas Martinaitis
    Art/Art Studies, General
    1986 - 1990

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