Ahmed Elmenoufy, PhD, B Pharm

Research Scientist- Synthetic/Medicinal Chemistry at Dalriada Drug Discovery Inc. at Dalriada Drug Discovery
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Contact Information
us****@****om
(386) 825-5501
Location
Mississauga, Ontario, Canada, CA
Languages
  • English Full professional proficiency
  • Arabic Native or bilingual proficiency
  • French Elementary proficiency
  • Chinese Elementary proficiency

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Experience

    • Research Scientist- Synthetic/Medicinal Chemistry at Dalriada Drug Discovery Inc.
      • Jan 2021 - Present

      Duties and Responsibilities: * Design synthetic schemes, perform synthesis, purification and characterization of compounds.* Plan and perform SAR studies, procure and maintain inventory of reagent and consumables, maintain inventory of samples. * Operate and maintain LC-MS/MS, HPLC, and MS instruments, maintain and organize experimental data records, and ensure compliance with the regulatory and safety governmental and institutional requirements. * Provide… Duties and Responsibilities: * Design synthetic schemes, perform synthesis, purification and characterization of compounds.* Plan and perform SAR studies, procure and maintain inventory of reagent and consumables, maintain inventory of samples. * Operate and maintain LC-MS/MS, HPLC, and MS instruments, maintain and organize experimental data records, and ensure compliance with the regulatory and safety governmental and institutional requirements. * Provide needed training to employees and oversee their work, maintain well organized experimental and regulatory documentation, report to the company’s management team, maintain the organization and cleanliness of the laboratory space, maintain and arrange for all permits required for the operation of the lab, and maintain expense records. * Assist in the preparation of grant applications and assist with administrative duties. Show more Show less

    • Lecturer
      • Nov 2020 - Present

    • Assistant Lecturer
      • Oct 2015 - Oct 2020

    • Graduate Research And Teaching Assistant
      • Mar 2012 - Sep 2015

    • Research Scientist - Organic Chemistry at TC Scientific Inc.
      • May 2020 - Dec 2020

      I carried out various reactions as following: * Nucleophilic substitution reactions in a scale from 20 to 60 gm.* Grignard addition reactions and oxidation & reduction reactions using various mild conditions.* Conducted structure activity relationship of the inhibitors up to 120 gm scale by telescoped routes. * Cross coupling reactions such as Buchwald-Hartwig amination reactions. * Isotope labeling reactions using 15N and 13C for biological evaluation. * O and N… I carried out various reactions as following: * Nucleophilic substitution reactions in a scale from 20 to 60 gm.* Grignard addition reactions and oxidation & reduction reactions using various mild conditions.* Conducted structure activity relationship of the inhibitors up to 120 gm scale by telescoped routes. * Cross coupling reactions such as Buchwald-Hartwig amination reactions. * Isotope labeling reactions using 15N and 13C for biological evaluation. * O and N demethylation reactions.* Protection and deprotection of diverse of functional groups.* Amide coupling reactions * Click reactions such as copper(I)-catalyzed azide alkyne cycloaddition (CuAAC) in a scale of 150 gm. Show more Show less

    • Research And Teaching Assistant
      • Sep 2015 - May 2020

      - Teaching Duties: Taught the lab and experimental techniques in the following courses:* 09/2016- 04/2020: Teaching Assistant, Dept. of Chemistry, University of Alberta, Canada. Course: CHEM 261 (Introductory Organic Chemistry), TA ranking is Excellent. * 09/ 2015: Teaching Assistant, Dept. of Chemistry, University of Alberta, Canada. Course: CHEM 101 (General Chemistry).- Research Duties: Design, Synthesis and Biological Evaluation of Inhibitors of DNA Targeted… - Teaching Duties: Taught the lab and experimental techniques in the following courses:* 09/2016- 04/2020: Teaching Assistant, Dept. of Chemistry, University of Alberta, Canada. Course: CHEM 261 (Introductory Organic Chemistry), TA ranking is Excellent. * 09/ 2015: Teaching Assistant, Dept. of Chemistry, University of Alberta, Canada. Course: CHEM 101 (General Chemistry).- Research Duties: Design, Synthesis and Biological Evaluation of Inhibitors of DNA Targeted Repair Proteins (ERCC-XPF). Show more Show less

    • Pharmacy Assistant
      • Feb 2019 - Mar 2020

      - Gather and enter patient information and doctors' prescriptions in computer systems (Kroll software).- Assess prescriptions for completeness.- Prepare and package prescription medications.- Compound non-sterile pharmaceutical products.- Maintain prescription and inventory recordkeeping systems.- Maintain proper drug storage and security.

    • Research Assistant at National Engineering Research Center for Nanomedicine
      • Sep 2013 - Jun 2015

      I was appointed as a Research Assistant in National Engineering Research Center for Nanomedicine, Wuhan, China. The research outcome as following:* Synthesized and characterized silica nanoparticles (SN) as carriers for drugs.* Functionalized the surface of SN with terminal amines.* Performed amide coupling chemistry between the amine and Rose Bengal drug using EDC/NHS chemistry.* Conducted in-vitro experiments to testify the validation of our modality in photodynamic… I was appointed as a Research Assistant in National Engineering Research Center for Nanomedicine, Wuhan, China. The research outcome as following:* Synthesized and characterized silica nanoparticles (SN) as carriers for drugs.* Functionalized the surface of SN with terminal amines.* Performed amide coupling chemistry between the amine and Rose Bengal drug using EDC/NHS chemistry.* Conducted in-vitro experiments to testify the validation of our modality in photodynamic therapy in treating deep-seated tumors. Show more Show less

    • Pharmacist
      • Aug 2011 - Mar 2013

      - Serves patients by preparing medications, giving pharmacological information to multidisciplinary health care team, and monitoring patient drug therapies.- Prepares medications by reviewing and interpreting physician orders and detecting therapeutic incompatibilities.- Dispenses medications by compounding, packaging, and labeling pharmaceuticals.- Controls medications by monitoring drug therapies; advising interventions.- Completes pharmacy operational requirements by… - Serves patients by preparing medications, giving pharmacological information to multidisciplinary health care team, and monitoring patient drug therapies.- Prepares medications by reviewing and interpreting physician orders and detecting therapeutic incompatibilities.- Dispenses medications by compounding, packaging, and labeling pharmaceuticals.- Controls medications by monitoring drug therapies; advising interventions.- Completes pharmacy operational requirements by organizing and directing technicians’ workflow, verifying their preparation and labeling of pharmaceuticals, and verifying order entries, charges, and inspections.- Provides pharmacological information by answering questions and requests of health care professionals and counseling patients on drug therapies.- Develops hospital staff’s pharmacological knowledge by participating in clinical programs and training pharmacy staff, students, interns, externs, residents, and health care professionals.- Complies with state and federal drug laws as regulated by the state board of pharmacy, the drug enforcement administration, and the food and drug administration by monitoring nursing unit inspection.- Maintains records for controlled substances and removes outdated and damaged drugs from the pharmacy inventory. Show more Show less

Education

  • University of Alberta
    -
  • Huazhong University of Science and Technology
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  • Misr University for Science and Technology
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