Adrián de Miguel Jiménez

PHD Student at INM-Leibniz Institute for New Materials
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Contact Information
us****@****om
(386) 825-5501
Location
Saarbrücken, Saarland, Duitsland
Languages
  • English Volledige professionele vaardigheid
  • French Basisvaardigheid
  • Spanish Moedertaal of tweetalig

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Experience

    • Germany
    • Research Services
    • 1 - 100 Employee
    • PHD Student
      • jun. 2019 - - heden

      Field: Organic Chemistry and Materials ScienceProject summary: The aim is to develop and optimize hydrogels for 3D cell culture models, 3D bioprinting and drug testing. I synthesize small molecules that act as crosslinkers in the formation of hydrogels after attaching them to synthetic or natural backbones (such as PEG or HA). I also work on improving the reproducibilty of the hydrogels by automating liquid handling. In addition, I test the hydrogels in 3D bioprinting and check the chemical and physical properties in order to improve the formulation.Dynamic BiomaterialsSupervisor: Prof Dr Aránzazu del Campo and Dr Samuel Pearson

    • Master Thesis Student
      • jan. 2018 - jul. 2018

      Field: Computational Chemistry and Medicinal ChemistryProject summary: The aim was to prevent the Ebola virus to enter the human cells by blocking an essential protein-protein interaction. I studied the interaction between the human protein NPC1 and the Ebola’s glycoprotein (GP) by using different methods such as druggable pocket searching, docking and molecular dynamics.Supervisor: Prof Dr Ana Martínez, Dr Carmen Gil and Dr Nuria Campillo Field: Computational Chemistry and Medicinal ChemistryProject summary: The aim was to prevent the Ebola virus to enter the human cells by blocking an essential protein-protein interaction. I studied the interaction between the human protein NPC1 and the Ebola’s glycoprotein (GP) by using different methods such as druggable pocket searching, docking and molecular dynamics.Supervisor: Prof Dr Ana Martínez, Dr Carmen Gil and Dr Nuria Campillo

    • Spain
    • Research Services
    • 1 - 100 Employee
    • Bachelor Thesis Student
      • nov. 2016 - jul. 2017

      Field: Organic Chemistry and Medicinal ChemistryProject summary: The aim was to prevent the entry of the Influenza virus by blocking an essential interaction between the human enzyme TTSP and the spike HA from the virus. I synthesized novel compounds by multicomponent reaction Ugi-3C and other methodologies in organic synthesis.Supervisor: Prof Dr María José Camarasa and Dr Sonsoles Velázquez Field: Organic Chemistry and Medicinal ChemistryProject summary: The aim was to prevent the entry of the Influenza virus by blocking an essential interaction between the human enzyme TTSP and the spike HA from the virus. I synthesized novel compounds by multicomponent reaction Ugi-3C and other methodologies in organic synthesis.Supervisor: Prof Dr María José Camarasa and Dr Sonsoles Velázquez

    • Bachelor Internship Student
      • jun. 2016 - jul. 2016

      Field: Organic Chemistry, Biochemistry and Medicinal ChemistryProject summary: Synthesis of indol based compounds under inert conditions and subsequent pharmacological evaluation on human neuroblastoma cells for the treatment of Alzheimer disease.Supervisor: Dr Cristóbal de los Ríos Field: Organic Chemistry, Biochemistry and Medicinal ChemistryProject summary: Synthesis of indol based compounds under inert conditions and subsequent pharmacological evaluation on human neuroblastoma cells for the treatment of Alzheimer disease.Supervisor: Dr Cristóbal de los Ríos

Education

  • Universidad Complutense de Madrid, Universidad de Alcalá and Universidad CEU San Pablo
    Master in Drug Discovery
    2017 - 2018
  • Universidad Autónoma de Madrid
    Bachelor in Chemistry
    2013 - 2017

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