Aaron Chadderdon
Scientist at TSRL, Inc- Claim this Profile
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English -
Topline Score
Bio
Experience
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TSRL, Inc
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United States
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Scientist
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Jan 2021 - Present
• Manage daily operations of in vivo facilities • Serve as Study Director; point of contact for external collaborators/CROs • Participate in the design of in vivo research projects and write study protocols • Plan and conduct in vivo pharmacokinetic and toxicology experimental procedures independently • Learn and/or develop new surgical techniques and experimental procedures for in vivo studies as needed• Perform LCMS/MS analytical method development, evaluation, and qualification • Prepare in vivo samples for analysis• Analyze samples via LCMS/MS in compliance with established methods and requirements • Process data using appropriate statistical tools and participate in data QC and data presentations • Responsible for design, development, and implementation of all in vitro assays for grants and research projects • Prepare written reports of completed studies• Participate in development and revision of SOPs• Perform calibration and maintenance of equipment• Literature review • Serve on IACUC• Train new lab members • Assist with SBIR/STTR grant preparation
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Associate Scientist
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Oct 2017 - Dec 2020
• Manage daily operations of in vivo facilities • Serve as Study Director• Participate in the design of in vivo research projects and write study protocols • Plan and conduct in vivo pharmacokinetic and toxicology experimental procedures independently • Learn and/or develop new surgical techniques and experimental procedures for in vivo studies as needed• Prepare in vivo samples for analysis• Analyze samples via LCMS/MS and process data using appropriate statistical tools and participate in data QC and data presentations • Responsible for design, development, and implementation of all in vitro assays for grants and research projects • Prepare written reports of completed studies• Participate in development and revision of SOPs• Perform calibration and maintenance of equipment• Serve on IACUC• Train new lab members • Assist with SBIR/STTR grant preparation
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University of Michigan Medical School
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United States
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Higher Education
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700 & Above Employee
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Research Specialist Associate/Laboratory Manager
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Aug 2015 - Oct 2017
• Primary lab contact for OSEH and ULAM communications and inspections; serve as laboratory safety officer and chemical hygiene officer • In charge of radiation, chemical and biological safety/regulatory compliance within the laboratory; responsible for acquisition and disposal of these substances • Responsible for protocol and SOP management • Responsible for ordering equipment, animals and all other laboratory supplies • Responsible for equipment maintenance, general lab maintenance and arranging repairs • Upkeep of controlled substance inventory, records and use logs • Prepare schedule for laboratory data meetings and presentations • Responsible for maintaining lab members personnel and training records; assist with training of new lab members • Perform behavioral assays in mice (hot plate, von Frey, constipation and acetic acid stretch assays)• Mouse colony management and genotyping; transfer of animals between facilities • Perform tissue dissection and preparation, specializing in CNS dissection • Perform western blots• Perform mammalian cell culture and membrane preparation • Perform in vitro compound screening with radioligand binding and efficacy assays (competition and G protein binding assays) • Assist other lab members with experiments as necessary • Record, organize, analyze and present experimental data • Assist with manuscript preparation
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University of Michigan
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United States
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Higher Education
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700 & Above Employee
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Research Associate I
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Jan 2015 - Aug 2015
• Perform behavioral assays in rats (forced swim test, drug self-administration and locomotor activity assays) • Perform in vitro compound screening with radioligand binding and efficacy assays (competition and G protein binding assays) • Record, organize, analyze and present experimental data • Prepare manuscripts • Perform behavioral assays in rats (forced swim test, drug self-administration and locomotor activity assays) • Perform in vitro compound screening with radioligand binding and efficacy assays (competition and G protein binding assays) • Record, organize, analyze and present experimental data • Prepare manuscripts
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Education
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University of Michigan Medical School
Master of Science (MS), Pharmacology -
Oakland Community College
Biology and Chemistry -
University of Michigan
Bachelor of Science - BS, Brain, Behavior, and Cognitive Science