Ariel Isser
Senior Scientist at Regeneron- Claim this Profile
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English Native or bilingual proficiency
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Hebrew Professional working proficiency
Topline Score
Bio
Experience
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Regeneron
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United States
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Biotechnology
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700 & Above Employee
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Senior Scientist
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Mar 2023 - Present
TCR Discovery
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Associate Scientist
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Jun 2022 - Present
TCR Discovery
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The Johns Hopkins University School of Medicine
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United States
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Hospitals and Health Care
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700 & Above Employee
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Biomedical Engineering PhD Candidate - Schneck Laboratory
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Aug 2016 - Jun 2022
• Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer… Show more • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer immunotherapy. • Directly mentored 3 undergraduate, 9 graduate, and 1 postdoctoral researcher. • Helped in writing and data collection for funded R01, R33, and P41 grants. Show less • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer… Show more • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer immunotherapy. • Directly mentored 3 undergraduate, 9 graduate, and 1 postdoctoral researcher. • Helped in writing and data collection for funded R01, R33, and P41 grants. Show less
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Johns Hopkins BME Extramural Development in Graduate Education (BME EDGE)
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Baltimore, Maryland, United States
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Co-Chair
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Jun 2017 - Jun 2021
Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional… Show more Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional development events. Webmaster (June 2017 - June 2018) • Re-designed the BME EDGE website. Show less Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional… Show more Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional development events. Webmaster (June 2017 - June 2018) • Re-designed the BME EDGE website. Show less
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University of Maryland
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Research Assistant
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Aug 2014 - Aug 2016
• Studied free energy of mixing and clustering behavior of ionic liquids in organic solvents in the presence of carbohydrate chains using Molecular Dynamics simulations. • Synthesized pH-sensitive bilayer polymer squares through spin-coating, thermal annealing, and photolithography. • Characterized surface morphology with optical and atomic force microscopy. • Studied free energy of mixing and clustering behavior of ionic liquids in organic solvents in the presence of carbohydrate chains using Molecular Dynamics simulations. • Synthesized pH-sensitive bilayer polymer squares through spin-coating, thermal annealing, and photolithography. • Characterized surface morphology with optical and atomic force microscopy.
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Alpha Eta Mu Beta National Biomedical Engineering Honor Society
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Biotechnology Research
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1 - 100 Employee
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Founding Vice President of Academic Affairs
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Sep 2015 - May 2016
• Co-founder of UMD Chapter - helped draft constitution, elect first board, and recruit members. • Established and coordinated departmental tutoring and peer academic advising programs. • Co-founder of UMD Chapter - helped draft constitution, elect first board, and recruit members. • Established and coordinated departmental tutoring and peer academic advising programs.
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Melvin J. Berman Hebrew Academy
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United States
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Education Administration Programs
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1 - 100 Employee
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Computer Science Teacher
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Sep 2015 - May 2016
Designed and taught an after-school programming course in Python to middle school students. Designed and taught an after-school programming course in Python to middle school students.
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National Institute of Standards and Technology (NIST)
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United States
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Research Services
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700 & Above Employee
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Summer Undergraduate Research Fellow
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May 2015 - Aug 2015
• Created Python Wrapper for Molecular Dynamics Software and developed algorithms to predict bulk properties of organic liquids. • Created Python Wrapper for Molecular Dynamics Software and developed algorithms to predict bulk properties of organic liquids.
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National Institute of Standards and Technology (NIST)
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United States
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Research Services
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700 & Above Employee
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Summer Undergraduate Research Fellow
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May 2014 - Aug 2014
• Performed liquid silane deposition, spin-coating, and grafting out of solution to synthesize polymer brushes. • Studied brushes with variable angle spectroscopic ellipsometry and atomic force microscopy. • Performed liquid silane deposition, spin-coating, and grafting out of solution to synthesize polymer brushes. • Studied brushes with variable angle spectroscopic ellipsometry and atomic force microscopy.
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University of Maryland
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Research Assistant
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Jun 2012 - Jan 2014
• Created a microfluidic device and computer vision software for imaging and sorting C. Elegans nematodes. • Designed and built a LabVIEW-based system to measure magnetic fields three-dimensionally. • Created a microfluidic device and computer vision software for imaging and sorting C. Elegans nematodes. • Designed and built a LabVIEW-based system to measure magnetic fields three-dimensionally.
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FDA
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United States
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Government Administration
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700 & Above Employee
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Research Assistant
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Jun 2010 - Aug 2010
Conducted monoclonal antibody purification, protein assays, gel electrophoresis, virus purification through sucrose gradients, enzyme-linked immunosorbent assays, competition and virus neutralization assays. Conducted monoclonal antibody purification, protein assays, gel electrophoresis, virus purification through sucrose gradients, enzyme-linked immunosorbent assays, competition and virus neutralization assays.
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Education
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The Johns Hopkins University School of Medicine
Doctor of Philosophy (Ph.D.), Biomedical Engineering -
University of Maryland College Park
Bachelor’s Degree, Bioengineering