Ariel Isser

Senior Scientist at Regeneron
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Contact Information
us****@****om
(386) 825-5501
Location
Teaneck, New Jersey, United States, JE
Languages
  • English Native or bilingual proficiency
  • Hebrew Professional working proficiency

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Experience

    • United States
    • Biotechnology
    • 700 & Above Employee
    • Senior Scientist
      • Mar 2023 - Present

      TCR Discovery

    • Associate Scientist
      • Jun 2022 - Present

      TCR Discovery

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Biomedical Engineering PhD Candidate - Schneck Laboratory
      • Aug 2016 - Jun 2022

      • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer… Show more • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer immunotherapy. • Directly mentored 3 undergraduate, 9 graduate, and 1 postdoctoral researcher. • Helped in writing and data collection for funded R01, R33, and P41 grants. Show less • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer… Show more • Designed and patented nanoparticle technology that recruits T cell help to augment existing cancer immunotherapies, in collaboration with 5 national and international laboratories. • Developed and patented high-throughput approaches for targeting and identifying tumor-specific T cells. • Provided the first demonstration of cross-reactivity between gut microbes and tumor antigens. • Identified unique T cell receptor sequences associated with responses to cancer immunotherapy. • Directly mentored 3 undergraduate, 9 graduate, and 1 postdoctoral researcher. • Helped in writing and data collection for funded R01, R33, and P41 grants. Show less

    • Co-Chair
      • Jun 2017 - Jun 2021

      Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional… Show more Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional development events. Webmaster (June 2017 - June 2018) • Re-designed the BME EDGE website. Show less Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional… Show more Co-Chair (June 2019 - June 2021) • Led a 13-member student group to coordinate graduate internship program, professional workshops, and career talks, overseeing 12 student interns and 30+ events serving nearly 600 students. • Spearheaded departmental changes to Individual Development Plans with Ph.D. program director. • Raised $13,500 in annual funding to support BME EDGE activities. Professional Development Chair (June 2018 - June 2019) • Organized monthly professional development events. Webmaster (June 2017 - June 2018) • Re-designed the BME EDGE website. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Aug 2014 - Aug 2016

      • Studied free energy of mixing and clustering behavior of ionic liquids in organic solvents in the presence of carbohydrate chains using Molecular Dynamics simulations. • Synthesized pH-sensitive bilayer polymer squares through spin-coating, thermal annealing, and photolithography. • Characterized surface morphology with optical and atomic force microscopy. • Studied free energy of mixing and clustering behavior of ionic liquids in organic solvents in the presence of carbohydrate chains using Molecular Dynamics simulations. • Synthesized pH-sensitive bilayer polymer squares through spin-coating, thermal annealing, and photolithography. • Characterized surface morphology with optical and atomic force microscopy.

    • Founding Vice President of Academic Affairs
      • Sep 2015 - May 2016

      • Co-founder of UMD Chapter - helped draft constitution, elect first board, and recruit members. • Established and coordinated departmental tutoring and peer academic advising programs. • Co-founder of UMD Chapter - helped draft constitution, elect first board, and recruit members. • Established and coordinated departmental tutoring and peer academic advising programs.

    • United States
    • Education Administration Programs
    • 1 - 100 Employee
    • Computer Science Teacher
      • Sep 2015 - May 2016

      Designed and taught an after-school programming course in Python to middle school students. Designed and taught an after-school programming course in Python to middle school students.

    • United States
    • Research Services
    • 700 & Above Employee
    • Summer Undergraduate Research Fellow
      • May 2015 - Aug 2015

      • Created Python Wrapper for Molecular Dynamics Software and developed algorithms to predict bulk properties of organic liquids. • Created Python Wrapper for Molecular Dynamics Software and developed algorithms to predict bulk properties of organic liquids.

    • United States
    • Research Services
    • 700 & Above Employee
    • Summer Undergraduate Research Fellow
      • May 2014 - Aug 2014

      • Performed liquid silane deposition, spin-coating, and grafting out of solution to synthesize polymer brushes. • Studied brushes with variable angle spectroscopic ellipsometry and atomic force microscopy. • Performed liquid silane deposition, spin-coating, and grafting out of solution to synthesize polymer brushes. • Studied brushes with variable angle spectroscopic ellipsometry and atomic force microscopy.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Jun 2012 - Jan 2014

      • Created a microfluidic device and computer vision software for imaging and sorting C. Elegans nematodes. • Designed and built a LabVIEW-based system to measure magnetic fields three-dimensionally. • Created a microfluidic device and computer vision software for imaging and sorting C. Elegans nematodes. • Designed and built a LabVIEW-based system to measure magnetic fields three-dimensionally.

    • United States
    • Government Administration
    • 700 & Above Employee
    • Research Assistant
      • Jun 2010 - Aug 2010

      Conducted monoclonal antibody purification, protein assays, gel electrophoresis, virus purification through sucrose gradients, enzyme-linked immunosorbent assays, competition and virus neutralization assays. Conducted monoclonal antibody purification, protein assays, gel electrophoresis, virus purification through sucrose gradients, enzyme-linked immunosorbent assays, competition and virus neutralization assays.

Education

  • The Johns Hopkins University School of Medicine
    Doctor of Philosophy (Ph.D.), Biomedical Engineering
    2016 - 2022
  • University of Maryland College Park
    Bachelor’s Degree, Bioengineering
    2012 - 2016

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