Sean Rowley

Manager I/Bioanalytical Project Manager at BioAgilytix
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Contact Information
us****@****om
(386) 825-5501
Location
Durham, North Carolina, United States, US
Languages
  • English Native or bilingual proficiency

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Bio

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Credentials

  • Diversity and Inclusion in a Global Enterprise
    LinkedIn
    Jun, 2021
    - Nov, 2024
  • Diversity, Inclusion, and Belonging
    LinkedIn
    Jun, 2021
    - Nov, 2024

Experience

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Manager I/Bioanalytical Project Manager
      • Apr 2023 - Present

      Working to develop and validate immunogenic and neutralizing antibody (NAb) cell-based assays for preclinical drug approval according to GLP regulatory guidelines. Work closely with clients to assure successful on time execution of assays, validation and sample analysis under GxPs.

    • Scientist III/Bioanalytical Project Manager
      • Aug 2020 - Apr 2023

      Working to develop, qualify, and validate immunogenic and neutralizing antibody (NAb) cell-based assays for pre-clinical drug screening.

    • Scientist II
      • Apr 2018 - Aug 2020

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist II
      • Jan 2016 - Mar 2018

      Worked to develop and optimize novel in vitro cell-based assays aimed at supporting and advancing new human systems biology based approaches to chemical compound safety and efficacy testing. Specific work focused on utilizing human cell-based assay development to test the efficacy and risk assessment of key compounds in areas of DNA damage induction, skin sensitization, and endocrine disruption. Worked to develop and optimize novel in vitro cell-based assays aimed at supporting and advancing new human systems biology based approaches to chemical compound safety and efficacy testing. Specific work focused on utilizing human cell-based assay development to test the efficacy and risk assessment of key compounds in areas of DNA damage induction, skin sensitization, and endocrine disruption.

    • United States
    • Research Services
    • 1 - 100 Employee
    • Research Associate
      • May 2013 - Dec 2015

      Main efforts focused on the development and optimization of novel in vitro chemical toxicity screening assays to evaluate chemical safety and human risk assessment. In particular, major projects involved the development of in vitro molecular assays in a human cell line based system to assess chemical-induced DNA damage pathway activation and help formulate dose response safety recommendations. Additionally provided technical expertise on other related Hamner projects to advance the goals… Show more Main efforts focused on the development and optimization of novel in vitro chemical toxicity screening assays to evaluate chemical safety and human risk assessment. In particular, major projects involved the development of in vitro molecular assays in a human cell line based system to assess chemical-induced DNA damage pathway activation and help formulate dose response safety recommendations. Additionally provided technical expertise on other related Hamner projects to advance the goals of affiliated industry sponsors. Show less Main efforts focused on the development and optimization of novel in vitro chemical toxicity screening assays to evaluate chemical safety and human risk assessment. In particular, major projects involved the development of in vitro molecular assays in a human cell line based system to assess chemical-induced DNA damage pathway activation and help formulate dose response safety recommendations. Additionally provided technical expertise on other related Hamner projects to advance the goals… Show more Main efforts focused on the development and optimization of novel in vitro chemical toxicity screening assays to evaluate chemical safety and human risk assessment. In particular, major projects involved the development of in vitro molecular assays in a human cell line based system to assess chemical-induced DNA damage pathway activation and help formulate dose response safety recommendations. Additionally provided technical expertise on other related Hamner projects to advance the goals of affiliated industry sponsors. Show less

    • Higher Education
    • 700 & Above Employee
    • Research Technician III
      • Jan 2013 - May 2013

      Worked as Research Technician in the laboratory of Dr. Wendy Watford. This position was an extension of graduate research work performed in the lab. Research centered on the planning and execution of various laboratory experiments to support the publication of two manuscripts related to the Master’s thesis project involving the characterization of the role of the protein kinase Tpl2 (MAP3K8) in the innate inflammatory immune response.

    • Graduate Research Assistant
      • Aug 2010 - Dec 2012

      Graduate Student with Dr. Wendy Watford (2011-2012) Laboratory focus was aimed at understanding the mechanisms that regulate host defense and tolerance during the inflammatory response. Thesis Project involved characterizing the role of the protein kinase Tpl2 (MAP3K8) on innate immune cell functions during the inflammatory response. Graduate Student with Dr. Harry Dickerson (2010) Laboratory focused on the mucosal immune response of channel catfish to the protozoan… Show more Graduate Student with Dr. Wendy Watford (2011-2012) Laboratory focus was aimed at understanding the mechanisms that regulate host defense and tolerance during the inflammatory response. Thesis Project involved characterizing the role of the protein kinase Tpl2 (MAP3K8) on innate immune cell functions during the inflammatory response. Graduate Student with Dr. Harry Dickerson (2010) Laboratory focused on the mucosal immune response of channel catfish to the protozoan parasite Ichthyophthirius multifiliis. During Master’s rotation in the lab, studied the immune response and cellular infiltration at mucosal sites in catfish infected with the I. multifiliis parasite. Graduate Student with Dr. Liliana Jaso-Friedmann (2010) Laboratory focused on the mechanisms by which natural killer cells are activated and the molecules produced by activated natural killer cells. During Master’s rotation in the lab, performed various experimental tasks to assess the roles of NK cells during the innate immune response using a catfish model.

  • Perimeter Primary Care
    • Sandy Springs, GA
    • Medical Assistant
      • Aug 2009 - Jul 2010

      Assisted in preparing patients for medical exams and performed in-office procedures. Also, recorded patient vitals, updated medical histories, and managed patient charts. Assisted in preparing patients for medical exams and performed in-office procedures. Also, recorded patient vitals, updated medical histories, and managed patient charts.

Education

  • The University of Georgia
    Master of Science (M.S.), Veterinary and Biomedical Sciences
    2010 - 2012
  • The University of Georgia
    Bachelor of Science (B.S.), Biology
    2005 - 2009

Community

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