Bo Lu
Principal Bioinformatics Scientist at Pleno Inc.- Claim this Profile
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Bio
Experience
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Pleno Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Principal Bioinformatics Scientist
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Sep 2022 - Present
- Tech lead, software architect for high performance image analysis, informatics and asynchronous control systems - Informatics and image analysis algorithm development in Python with Rust and C++ FFI with pybind and PyO3, - High performance heterogenous software architecture design & implementation, acceleration using FPGA, CUDA, JAX and other acceleration technologies - Signal processing, machine learning, statistical inference algorithm development and productization - Tech lead, software architect for high performance image analysis, informatics and asynchronous control systems - Informatics and image analysis algorithm development in Python with Rust and C++ FFI with pybind and PyO3, - High performance heterogenous software architecture design & implementation, acceleration using FPGA, CUDA, JAX and other acceleration technologies - Signal processing, machine learning, statistical inference algorithm development and productization
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Illumina
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United States
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Biotechnology Research
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700 & Above Employee
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Staff Bioinformatics Scientist
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Apr 2022 - Sep 2022
- Developed real time image analysis and basecalling pipelines for next-generation sequencing systems - Algorithms (image analysis, super resolution, machine learning) prototyping, optimization, and production software development utilizing state of art languages and tools (modern C++, C#, CUDA, and Python) - Developed end to end analysis metric generation, IO & and visualization in C++, Python, React, and Typescript - Two time recipient of the annual Illumina Innovation Awards in… Show more - Developed real time image analysis and basecalling pipelines for next-generation sequencing systems - Algorithms (image analysis, super resolution, machine learning) prototyping, optimization, and production software development utilizing state of art languages and tools (modern C++, C#, CUDA, and Python) - Developed end to end analysis metric generation, IO & and visualization in C++, Python, React, and Typescript - Two time recipient of the annual Illumina Innovation Awards in 2020 and 2021 for work in super-resolution reconstruction and improving basecalling accuracy - PDP core team rep for primary analysis & bioinformatics for an upcoming platform project (200 FTE+)
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Senior Bioinformatics Scientist
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Jul 2020 - Apr 2022
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Bioinformatics Scientist I & II
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Oct 2017 - Jul 2020
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Dow
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United States
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Chemical Manufacturing
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700 & Above Employee
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Associate Analytics Manager
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Jul 2017 - Oct 2017
- Provided machine learning and multivariate modeling support to troubleshoot high-priority plant issues, improve reliability and optimize asset utilization for Dow's global operations using process historian data; combined project value estimated to be ~20$MM - Developed and deployed model-based batch adaptive control applications (in C#) to improve process capability in food and pharmaceutical processes - Led the adoption of open source data science tools internally, developed interop… Show more - Provided machine learning and multivariate modeling support to troubleshoot high-priority plant issues, improve reliability and optimize asset utilization for Dow's global operations using process historian data; combined project value estimated to be ~20$MM - Developed and deployed model-based batch adaptive control applications (in C#) to improve process capability in food and pharmaceutical processes - Led the adoption of open source data science tools internally, developed interop libraries to provide convenient process data historians access through Python and Pandas - Led research collaboration projects with University partners and internal teams to develop DL transfer learning models (ResNet / ImageNet) for manufacturing process quality control
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Senior Engineer
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Jan 2015 - Jul 2017
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The University of Texas at Austin
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United States
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Higher Education
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700 & Above Employee
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Graduate Research Assistant
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Sep 2011 - May 2015
- Virtual metrology of plasma etch processes in semiconductor fabs - Nonlinear control optimization and fault detection of run-to-run control systems - Research Adviser: Dr. Thomas F. Edgar - 11 journal publications (6 first author) - Virtual metrology of plasma etch processes in semiconductor fabs - Nonlinear control optimization and fault detection of run-to-run control systems - Research Adviser: Dr. Thomas F. Edgar - 11 journal publications (6 first author)
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Education
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The University of Texas at Austin
Doctor of Philosophy (Ph.D.), Chemical Engineering -
University of Alberta
Bachelor, Chemical Engineering w/ Minor in Comp. Sci.