Minkyu Kim, Ph.D.
Associate Professor at University of Arizona- Claim this Profile
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Bio
Experience
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University of Arizona
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United States
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Higher Education
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700 & Above Employee
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Associate Professor
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Jul 2023 - Present
- Department of Materials Science and Engineering- Department of Biomedical Engineering- The BIO5 Institute
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Assistant Professor
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Jul 2016 - Jun 2023
- Department of Materials Science and Engineering- Department of Biomedical Engineering- The BIO5 Institute
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Massachusetts Institute of Technology
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Associate
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Jul 2012 - Jun 2016
• Invented first artificial protein polymer hydrogel that acts as a selective biomolecule filter - Conceptualized and developed a method to selectively sequester biological warfare agents - Developed scale-up synthesis process using synthetic biology (~70-fold higher than natural hydrogel analogue) - Earned first rank evaluation at annual review meeting in Defense Threat Reduction Agency (DTRA) headquarters (2014) • Invented simple and safe formulation for decontamination of chemical warfare agents on aircraft surfaces - Discovered the self-assembly of inexpensive, commercially available amphiphilic block copolymers onto the organophosphorus hydrolase (OPH) enzyme, which detoxifies neurotoxic nerve agents; developed a co-assembly procedure which enhances enzyme activity (up to 40 %) and stability in various environments (organic solvents, high temperature, lifetime) - Developed high yielding OPH synthesis process • Determined the effect of electrostatics on the self-assembly of protein-polymer block copolymers for material design - Synthesized bioconjugates of 5 fluorescent proteins and one synthetic polymer (Poly (N-isopropylacrylamide) (PNIPAM)) using a combination of protein synthesis, reversible addition-fragmentation polymerization (RAFT), and thiol-maleimide chemistry; characterized their self-assembly behavior using synchrotron small-angle x-ray scattering (SAXS) • Published four first author publications, wrote one successful DTRA grant proposal and proposals for synchrotron SAXS time at the National Synchrotron Light Source Show less
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Duke University
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Associate
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May 2011 - Jun 2012
Design of Artificially Engineered Biopolymers and Nanoscale Biopolymer Physics
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Research Assistant
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Sep 2006 - Apr 2011
• Designed protein-based polymeric materials with advanced properties including muscle toughness and red blood cell reversible deformability - Discovered a new class of proteins with nanospring mechanical behavior using custom-built AFM-based single molecule force spectroscopy- Developed a route to controllably construct protein polymer architectures by utilizing self-assembled biopolymer complexes as material joints - Invented protein-based force probes to precisely measure the strength of self-assembled biopolymer complexes to identify strong crosslinkers for use in materials design - Designed and developed biosynthesis process of shock absorber and nanospring protein polymers• Effectively collaborated with the Chilkoti group in Biomedical Engineering to capture the real-space images of stimulus-responsive biopolymer micelle structures relevant to drug delivery• Published four first author publications (7 total) Show less
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Research Assistant
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Sep 2004 - Aug 2006
Research Topic: Analysis of the mechanical properties of single cells via atomic force microscopy (AFM) and total internal reflection fluorescence microscopy (TIRFM)
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8th U.S. ARMY, 2nd Infantry Division, 44th Engineer Battalion, S4 (Logistics)
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Camp Howze, S. Korea
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Non-Commissioned Officer (Sergeant), KATUSA
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Aug 1998 - Aug 2000
• Coordinated military vehicle movements and managed logistics within the battalion as interim section leader • Reduced the budget for the battalion (valued over $50k) by searching out, negotiating, and coordinating vendors for all locally procured items • Supervised U.S. and Korean soldiers • Coordinated military vehicle movements and managed logistics within the battalion as interim section leader • Reduced the budget for the battalion (valued over $50k) by searching out, negotiating, and coordinating vendors for all locally procured items • Supervised U.S. and Korean soldiers
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Education
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Duke University
PhD, Mechanical Engineering and Materials Science -
Duke University
MS, Biomedical Engineering -
Kyung Hee University
BS, Mechanical Engineering