Minkyu Kim, Ph.D.

Associate Professor at University of Arizona
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Contact Information
us****@****om
(386) 825-5501
Location
Tucson, Arizona, United States, US

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Experience

    • United States
    • Higher Education
    • 700 & Above Employee
    • Associate Professor
      • Jul 2023 - Present

      - Department of Materials Science and Engineering- Department of Biomedical Engineering- The BIO5 Institute

    • Assistant Professor
      • Jul 2016 - Jun 2023

      - Department of Materials Science and Engineering- Department of Biomedical Engineering- The BIO5 Institute

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • Jul 2012 - Jun 2016

      • Invented first artificial protein polymer hydrogel that acts as a selective biomolecule filter - Conceptualized and developed a method to selectively sequester biological warfare agents - Developed scale-up synthesis process using synthetic biology (~70-fold higher than natural hydrogel analogue) - Earned first rank evaluation at annual review meeting in Defense Threat Reduction Agency (DTRA) headquarters (2014) • Invented simple and safe formulation for decontamination of chemical warfare agents on aircraft surfaces - Discovered the self-assembly of inexpensive, commercially available amphiphilic block copolymers onto the organophosphorus hydrolase (OPH) enzyme, which detoxifies neurotoxic nerve agents; developed a co-assembly procedure which enhances enzyme activity (up to 40 %) and stability in various environments (organic solvents, high temperature, lifetime) - Developed high yielding OPH synthesis process • Determined the effect of electrostatics on the self-assembly of protein-polymer block copolymers for material design - Synthesized bioconjugates of 5 fluorescent proteins and one synthetic polymer (Poly (N-isopropylacrylamide) (PNIPAM)) using a combination of protein synthesis, reversible addition-fragmentation polymerization (RAFT), and thiol-maleimide chemistry; characterized their self-assembly behavior using synchrotron small-angle x-ray scattering (SAXS) • Published four first author publications, wrote one successful DTRA grant proposal and proposals for synchrotron SAXS time at the National Synchrotron Light Source Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • May 2011 - Jun 2012

      Design of Artificially Engineered Biopolymers and Nanoscale Biopolymer Physics

    • Research Assistant
      • Sep 2006 - Apr 2011

      • Designed protein-based polymeric materials with advanced properties including muscle toughness and red blood cell reversible deformability - Discovered a new class of proteins with nanospring mechanical behavior using custom-built AFM-based single molecule force spectroscopy- Developed a route to controllably construct protein polymer architectures by utilizing self-assembled biopolymer complexes as material joints - Invented protein-based force probes to precisely measure the strength of self-assembled biopolymer complexes to identify strong crosslinkers for use in materials design - Designed and developed biosynthesis process of shock absorber and nanospring protein polymers• Effectively collaborated with the Chilkoti group in Biomedical Engineering to capture the real-space images of stimulus-responsive biopolymer micelle structures relevant to drug delivery• Published four first author publications (7 total) Show less

    • Research Assistant
      • Sep 2004 - Aug 2006

      Research Topic: Analysis of the mechanical properties of single cells via atomic force microscopy (AFM) and total internal reflection fluorescence microscopy (TIRFM)

    • Non-Commissioned Officer (Sergeant), KATUSA
      • Aug 1998 - Aug 2000

      • Coordinated military vehicle movements and managed logistics within the battalion as interim section leader • Reduced the budget for the battalion (valued over $50k) by searching out, negotiating, and coordinating vendors for all locally procured items • Supervised U.S. and Korean soldiers • Coordinated military vehicle movements and managed logistics within the battalion as interim section leader • Reduced the budget for the battalion (valued over $50k) by searching out, negotiating, and coordinating vendors for all locally procured items • Supervised U.S. and Korean soldiers

Education

  • Duke University
    PhD, Mechanical Engineering and Materials Science
    2006 - 2011
  • Duke University
    MS, Biomedical Engineering
    2004 - 2006
  • Kyung Hee University
    BS, Mechanical Engineering
    1997 - 2004

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