Experience

Sirnaomics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Scientist

  • Jan 2022 - Present

  In charge of LCMS analysis of oligonucleotide company-wide. 10nmol-200umol oligonucleotide solid-phase synthesis using MerMade 12, OligoPilot 100, ABI 392. Downstream purification on C18/desalting cartridges, prep-HPLC, or AKTA 600. Ion-pair/IEX HPLC, RP/HILIC/SEC LCMS characterization. siRNA synthesis and conjugation with targeting ligands. Nanoparticle formulation of siRNA with cationic peptides. In vitro analysis including cell culture, gene transfection, RNA extraction, qPCR, viability study, uptake, and imaging. Show less



Louisiana State University

• United States
• Higher Education
• 700 & Above Employee

• Research Assistant

  • Jun 2017 - Aug 2021

  Synthesis, characterization, and optimization of novel cancer drugs and imaging agents. Optimize the toxicity, uptake, and distribution by SAR-based structural modification. Cell study including cell-based assays and cell-imaging using fluorescence microscopy.Research lab maintenance.

• Instrument Assistant

  • May 2019 - Dec 2019

  Conducted accurate mass analysis using Agilent HPLC-ESI/APCI-TOF and MALDI-TOF (~ 500 samples).Performed daily calibration and maintenance of the Agilent 6230 instrument.Wrote the protocol for preparing samples and using Agilent mass detector software.

• Teaching & Solution Assistant

  • Aug 2016 - Dec 2018

  General Chemistry Lab & Organic Chemistry Lab