Kole DeGolier

Graduate Student, Immunology PhD Program at University of Colorado Anschutz Medical Campus
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Contact Information
us****@****om
(386) 825-5501
Location
Denver, Colorado, United States, US
Languages
  • Spanish Limited working proficiency

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Experience

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Student, Immunology PhD Program
      • Aug 2018 - Present

      Immunology PhD Program - Laboratory of Terry J. Fry, MDResearch Laboratory Rotations:-Jing Wang, PhD-Eduardo Davila, PhD Immunology PhD Program - Laboratory of Terry J. Fry, MDResearch Laboratory Rotations:-Jing Wang, PhD-Eduardo Davila, PhD

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Scientist
      • Feb 2017 - Jul 2018

      Laboratory of Dr. Courtney A. Crane, PhD (now employed by Mozart Therapeutics)• Cancer immunotherapy research developing a novel approach to locally deliver immunostimulatory factors to the tumor microenvironment of solid tumors using genetically engineered macrophages (GEMs)• Using GEMs as a tool to enhance proliferation and activation of chimeric antigen receptor T cells in solid tumors (Presented research at a Keystone Symposium in Whistler, BC, Canada. View poster below).• Studying T cell responses to immunostimulatory factors produced by GEMs• Characterizing natural killer cell function and phenotype after ex vivo expansion for adoptive cell transfer therapies• Characterizing the immune microenvironment and effector function of natural killer cells in diffuse intrinsic pontine glioma, a rare but incurable type of pediatric brain tumor• Assisting all members of the lab with murine in vivo studies and Chromium-51 release assays to profile function of effector cellsMy work in the Crane Lab has lead to multiple publications, listed in the "Publications" section below.

    • Research Associate
      • Jun 2016 - Feb 2017

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Scientist
      • Apr 2015 - Jun 2016

      My research at the Reh Lab involves retinal-cell reprogramming to treat retinal degenerative diseases. My focus is on high-throughput in-vitro screening using primary cell cultures and in-vivo validation of hundreds of small molecule compounds to reprogram mammalian photoreceptors, which has lead to a publication in eLife journal (see "Publications" section below). My research at the Reh Lab involves retinal-cell reprogramming to treat retinal degenerative diseases. My focus is on high-throughput in-vitro screening using primary cell cultures and in-vivo validation of hundreds of small molecule compounds to reprogram mammalian photoreceptors, which has lead to a publication in eLife journal (see "Publications" section below).

    • Undergraduate Research Assistant
      • Jun 2013 - Jun 2015

      Research to enhance Positron Emission Tomography techniques and sensor devices. My work has included studying the effects of sub-surface laser engraved interfaces in scintillator crystals on light transmission throughout the crystal and development of a device to profile the shape of a gamma ray beam emitted by a radioactive source. My main project while at the lab was the design and manufacture of a device to characterize the bi-directional scatter distribution function of laser light through a spherical scintillation crystal with sub surface laser engraved interfaces.

Education

  • University of Washington
    Bachelor of Science (B.S.), Biophysics
    2010 - 2015

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