Zachary Holtzapple, MD

Resident Physician at The University of Toledo College of Medicine and Life Sciences
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Contact Information
us****@****om
(386) 825-5501
Location
Ohio, United States, US

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Credentials

  • NIH Stroke Scale Certification
    American Heart Association
    Mar, 2021
    - Oct, 2024
  • OSHA 10 Hour Construction License
    ClickSafety
    Jan, 2018
    - Oct, 2024
  • Advanced Cardiovascular Life Support Basic Life Support
    American Heart Association
    Aug, 2020
    - Oct, 2024
  • Advanced Cardiac Life Support (ACLS)
    American Heart Association
    Feb, 2020
    - Oct, 2024

Experience

  • The University of Toledo College of Medicine and Life Sciences
    • United States
    • Higher Education
    • 200 - 300 Employee
    • Resident Physician
      • Jul 2022 - Present
  • The University of Toledo
    • Higher Education
    • 700 & Above Employee
    • Researcher in Department of Pulmonary Medicine and Department of Cardiovascular Medicine
      • Nov 2020 - Present

      Projects: • Correlating positive end-expiratory pressure (PEEP) of 8 to a decreased probability of ventilator associated event (VAE) • Clinical Characteristics and Outcomes of Non-ICU Hospitalization for COVID-19 • Meta-analysis review of pulmonary artery catheters (PAC) to mortality in patients with cardiogenic shock Projects: • Correlating positive end-expiratory pressure (PEEP) of 8 to a decreased probability of ventilator associated event (VAE) • Clinical Characteristics and Outcomes of Non-ICU Hospitalization for COVID-19 • Meta-analysis review of pulmonary artery catheters (PAC) to mortality in patients with cardiogenic shock

  • Lima Memorial Health System
    • United States
    • Hospitals and Health Care
    • 400 - 500 Employee
    • Researcher in Surgery Department
      • Jan 2018 - Nov 2021

      Project: Benefits Seen in Robotic-Assisted Surgery for Hernia Patients • Collect patient data and Intuitive Da Vinci Surgical System data on over 750 hernia surgery patients • Compare robotic, laparoscopic, and open procedures via conversion %, 30-day readmission %, and inpatient admissions • Present findings at annual conferences (Abdominal Wall Reconstruction and American College of Surgeons Conferences) Project: Benefits Seen in Robotic-Assisted Surgery for Hernia Patients • Collect patient data and Intuitive Da Vinci Surgical System data on over 750 hernia surgery patients • Compare robotic, laparoscopic, and open procedures via conversion %, 30-day readmission %, and inpatient admissions • Present findings at annual conferences (Abdominal Wall Reconstruction and American College of Surgeons Conferences)

    • Researcher in Cardiovascular Department
      • Aug 2018 - Aug 2019

      Project: CD-40 Receptor Effect on Fibrosis in Myocardial Tissue • Analyze Dahl-S Rat Model and CD-40 Knockout Rat Model cardiac fibrosis levels • Compare cardiac fibrosis in high-salt diet vs low-salt diet animal models • Participate in Medical Student Research Program (MSRP) coursework Project: CD-40 Receptor Effect on Fibrosis in Myocardial Tissue • Analyze Dahl-S Rat Model and CD-40 Knockout Rat Model cardiac fibrosis levels • Compare cardiac fibrosis in high-salt diet vs low-salt diet animal models • Participate in Medical Student Research Program (MSRP) coursework

  • Matrix Technologies, Inc.
    • United States
    • Automation Machinery Manufacturing
    • 200 - 300 Employee
    • Engineer I
      • Jan 2018 - Jun 2018

      • Designed two separate fast loop Sample Condition Systems (SCS) to different flare gas calorimeters for a petrochemical refining client • Devised a multidisciplinary sampling and mitigation plan for a petrochemical refining client's flare gas recycle compressor • Provided technical support and documentation on 53 different pressure relief devices in a petrochemical refinery client's newly designed amine units • Designed two separate fast loop Sample Condition Systems (SCS) to different flare gas calorimeters for a petrochemical refining client • Devised a multidisciplinary sampling and mitigation plan for a petrochemical refining client's flare gas recycle compressor • Provided technical support and documentation on 53 different pressure relief devices in a petrochemical refinery client's newly designed amine units

  • Toledo Refining Company LLC
    • United States
    • Oil and Gas
    • 100 - 200 Employee
    • Process Engineer Co-op (Unit Engineer)
      • Jan 2017 - May 2017

      • Provided day to day technical support and process moves to the refinery's naphtha splitter and the heavy naphtha and light naphtha desulfurization treaters for optimization • Reviewed and redlined operating procedures and guidelines for unit startups and shutdowns • Organized daily incident reports concerning process safety and occupational safety events • Provided day to day technical support and process moves to the refinery's naphtha splitter and the heavy naphtha and light naphtha desulfurization treaters for optimization • Reviewed and redlined operating procedures and guidelines for unit startups and shutdowns • Organized daily incident reports concerning process safety and occupational safety events

    • Undergraduate Research Assistant (Polyelectrolyte-Based Pharmaceuticals)
      • Aug 2016 - Dec 2016

      The research was based on developing data to further understand protein uptake and release from certain polyelectrolyte-based biological derivatives that are commonly used in pharmaceuticals. This was achieved by relating properties of ionically crosslinked polyelectrolyte nanospheres to their formation via photo-spectroscopy. Then analyzing correlations to find the solution parameters that govern their optimum structural formation and protein uptake.

    • Undergraduate Researcher Assistant (Neuroendocrine Cancer)
      • Feb 2015 - Aug 2016

      This research was conducted to monitor the metastatic behavior of glioblastoma cells. The metastatic behavior was induced by using arachidonic acid as a stimulant. While stimulating the cells, I used live cell imaging to record and analyze the correlation of calcium influx and release via hypothesized Orai-3 channels. As my work progressed, I used different agonists and antagonists to pinpoint the effectiveness of the hypothesized Orai-3 channels. Along with the research, I presented at lab meetings in front of medical students and doctoral candidates. Show less

    • Process Engineer Co-op (Energy & Economics)
      • May 2016 - Aug 2016

      • Managed a refinery-wide stream trap testing program (roughly 5000 steam traps) and analyzed testing results to deduce whether a given steam trap needed replaced or removed. • Worked with the Energy Coordinator to generate the annual refinery-wide energy budget • Performed monthly mass balances of the refinery fuel gas system including all of the refinery heaters to develop monthly, refinery-wide reports for energy consumption and heater efficiency • Managed a refinery-wide stream trap testing program (roughly 5000 steam traps) and analyzed testing results to deduce whether a given steam trap needed replaced or removed. • Worked with the Energy Coordinator to generate the annual refinery-wide energy budget • Performed monthly mass balances of the refinery fuel gas system including all of the refinery heaters to develop monthly, refinery-wide reports for energy consumption and heater efficiency

    • Process Engineer Co-op (Projects Engineer)
      • Aug 2015 - Jan 2016

      • Designed a turnaround project to consolidate the aromatic sewer system at our aromatic recovery unit • Tested and troubleshooted steam traps around the refinery to optimize energy efficiency in our refinery's steam system • Monitored dew points of air dryers to analyze correct cycling between dryers and to evaluate need for desiccant change out • Designed a turnaround project to consolidate the aromatic sewer system at our aromatic recovery unit • Tested and troubleshooted steam traps around the refinery to optimize energy efficiency in our refinery's steam system • Monitored dew points of air dryers to analyze correct cycling between dryers and to evaluate need for desiccant change out

    • Process Engineer Co-op (Introduction to Refining/Quality Assurance)
      • Jan 2015 - May 2015

      • Developed and updated heat exchanger monitoring spreadsheets utilizing Hysys models for accurate system parameters to plug into calculations of Overall Heat Transfer Coefficients to indicated fouling • Designed over 30 inferential models using process parameters for real time estimates of ASTM D86 distillation curves utilized by a Dynamic Matrix Control model • Created and updated Pi Graphic pages for widespread use among engineers • Developed and updated heat exchanger monitoring spreadsheets utilizing Hysys models for accurate system parameters to plug into calculations of Overall Heat Transfer Coefficients to indicated fouling • Designed over 30 inferential models using process parameters for real time estimates of ASTM D86 distillation curves utilized by a Dynamic Matrix Control model • Created and updated Pi Graphic pages for widespread use among engineers

Education

  • The University of Toledo
    Doctor of Medicine - MD, Medicine
    2018 - 2022
  • University of Toledo
    Bachelor of Applied Science (BASc), Chemical Engineering
    2013 - 2017

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