Léa THIEBAULT, PharmD, PhD

Clinical Project Leader - Scientific Advisor at ClinSearch
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Paris, Île-de-France, France, FR

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • France
    • Research Services
    • 1 - 100 Employee
    • Clinical Project Leader - Scientific Advisor
      • Mar 2023 - Present

    • France
    • Biotechnology
    • 1 - 100 Employee
      • Nov 2018 - Apr 2022

      - Application for ethical authorization in animal experimentation and evaluation by the ethics committee- Development of a in vivo AAV-based model to study promoter regulation in Age Macular Degeneration- Study of mutations using an iPS cells-based model in Age Macular DegenerationPublication: Klipfel L, Thiébault L, Cordonnier M, Clérin E, Blond F, Millet-Puel G, Mohand-Saïd S, Goureau O, Sahel JA, Nandrot EF, Léveillard T. A Splice Variant in SLC16A8 Gene Leads to Lactate Transport Deficit in Human iPS Cell-Derived Retinal Pigment Epithelial Cells. Cells. 2021 Jan 18 Show less

      • Nov 2017 - Nov 2018

      Study of the Natural History of Retinitis Pigmentosa, PHENOROD 1 study (NCT03975543), based on a retrospective study of patients' medical records, at the CHNO des Quinze-Vingts, INSERM-DGOS, Clinical Investigation Center 1423, Paris, FranceNatural history of Retinitis Pigmentosa caused by mutations in the RHO, PDE6A and PDE6B genes. Selection of inclusion and evaluation criteria for a clinical trial for a gene therapy drug. DES thesis defended in November 2019.

    • Vice-presidente
      • Nov 2016 - Oct 2018

      - Creation of 20 positions out of 70 for interns specializing in "Pharmaceutical Innovation and Research". - Follow-up of the course of the interns specialized in IPR - Organization of the General Assembly of pharmacy interns in biology and hospital pharmacy (200 interns) - Creation of 20 positions out of 70 for interns specializing in "Pharmaceutical Innovation and Research". - Follow-up of the course of the interns specialized in IPR - Organization of the General Assembly of pharmacy interns in biology and hospital pharmacy (200 interns)

    • France
    • Research Services
    • 1 - 100 Employee
    • Pharmacist Scientist in Translationnal Research
      • May 2017 - Oct 2017

      - Affaires Réglementaires : aide à la rédaction de la brochure investigateur et du document CMC de l’IMPD pour le patch de cellules de l’épithélium pigmentaire rétinien dérivées de cellules souches embryonnaires dans le traitement de la Rétinite Pigmentaire (NCT03963154). - Unité de recherche : mise au point d’une méthode de différentiation des cellules souches embryonnaires en épithélium pigmentaire rétinien selon des conditions GMP - Affaires Réglementaires : aide à la rédaction de la brochure investigateur et du document CMC de l’IMPD pour le patch de cellules de l’épithélium pigmentaire rétinien dérivées de cellules souches embryonnaires dans le traitement de la Rétinite Pigmentaire (NCT03963154). - Unité de recherche : mise au point d’une méthode de différentiation des cellules souches embryonnaires en épithélium pigmentaire rétinien selon des conditions GMP

    • France
    • Hospitals and Health Care
    • 700 & Above Employee
      • Nov 2016 - Apr 2017

      Gestion de la banque de sang de cordon

      • Jul 2016 - Oct 2016

      Development of a stem cell encapsulation method for a ready-to-use injectable preparation after thawing

    • France
    • Research Services
    • 700 & Above Employee
    • Master's internship
      • Jan 2016 - Jun 2016

      Development of a method using calcein AM to identify extracellular vesicles of cardiac progenitor cells derived from pluripotency-induced stem cells El Harane N, Kervadec A, Bellamy V, Pidial L, Neametalla HJ, Perier MC, Lima Correa B, Thiébault L, Cagnard N, Duché A, Brunaud C, Lemitre M, Gauthier J, Bourdillon AT, Renault MP, Hovhannisyan Y, Paiva S, Colas AR, Agbulut O, Hagège A, Silvestre JS, Menasché P, Renault NKE. Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors. Eur Heart J. 2018 May 21 Show less

    • France
    • Hospitals and Health Care
    • 700 & Above Employee
      • May 2015 - Oct 2015

      Validation des dosages pharmacologiques et toxicologiques

      • Nov 2014 - Apr 2015

      - Validation of pharmacological and toxicological assays- Therapeutic follow-up of patients treated with oral chemotherapies (tyrosine kinase inhibitors)- Development of an ELISA assay for plasma bevacizumab in patients with GliobastomaTabouret E, Rousseau B, Barrié M, Bequet C, Thiebault L, Chinot O and Hulin A. Bevacizumab Through Concentration in Recurrent Glioblastoma Patients. Journal of Integrative Oncology. 2015

    • Employé étudiant
      • Sep 2013 - Sep 2014

    • Extern
      • Oct 2011 - Sep 2012

      Publication : D. Le Guiner, L. Thiebault, D. Talon, F. Chast. Moindre efficacité de détergence des produits inactivants totaux ? Pharmacien Hospitalier et Clinicien 12/2012 ; 47(4):269–270. Publication : D. Le Guiner, L. Thiebault, D. Talon, F. Chast. Moindre efficacité de détergence des produits inactivants totaux ? Pharmacien Hospitalier et Clinicien 12/2012 ; 47(4):269–270.

    • Employé étudiant
      • Sep 2010 - Nov 2011

Education

  • Sorbonne Universités
    Doctor of Philosophy - PhD, Ecole Doctorale Cognition, Comportement, Cerveau
    2018 - 2022
  • Université Paris Descartes
    Diplôme d'Etudes Spécialisées, Innovation Pharmaceutique et Recherche
    2014 - 2019
  • Université de Paris
    Doctor of Pharmacy - PharmD, Pharmacie clinique, hospitalière et de réseau de soins
    2007 - 2019
  • Université Paris Descartes
    Diplôme Universitaire, Médicaments de Thérapie Innovante
    2017 - 2018
  • Université Paris Diderot
    Diplôme inter-universitaire, Thérapie Cellulaire
    2016 - 2017
  • Université Paris-Est Créteil (UPEC)
    Master 2 (M2), Biothérapie Tissulaire, Cellulaire et Génique
    2015 - 2016

Community

You need to have a working account to view this content. Click here to join now