Léa THIEBAULT, PharmD, PhD
Clinical Project Leader - Scientific Advisor at ClinSearch- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
Experience
-
ClinSearch SA/CAST®/EDClin™
-
France
-
Research Services
-
1 - 100 Employee
-
Clinical Project Leader - Scientific Advisor
-
Mar 2023 - Present
-
-
-
SparingVision
-
France
-
Biotechnology
-
1 - 100 Employee
-
-
Nov 2018 - Apr 2022
- Application for ethical authorization in animal experimentation and evaluation by the ethics committee- Development of a in vivo AAV-based model to study promoter regulation in Age Macular Degeneration- Study of mutations using an iPS cells-based model in Age Macular DegenerationPublication: Klipfel L, Thiébault L, Cordonnier M, Clérin E, Blond F, Millet-Puel G, Mohand-Saïd S, Goureau O, Sahel JA, Nandrot EF, Léveillard T. A Splice Variant in SLC16A8 Gene Leads to Lactate Transport Deficit in Human iPS Cell-Derived Retinal Pigment Epithelial Cells. Cells. 2021 Jan 18 Show less
-
-
-
Nov 2017 - Nov 2018
Study of the Natural History of Retinitis Pigmentosa, PHENOROD 1 study (NCT03975543), based on a retrospective study of patients' medical records, at the CHNO des Quinze-Vingts, INSERM-DGOS, Clinical Investigation Center 1423, Paris, FranceNatural history of Retinitis Pigmentosa caused by mutations in the RHO, PDE6A and PDE6B genes. Selection of inclusion and evaluation criteria for a clinical trial for a gene therapy drug. DES thesis defended in November 2019.
-
-
-
Syndicat des Internes en Pharmacie et Biologie Médicale des hôpitaux d'Île-de-France (SIPHIF)
-
France
-
Civic and Social Organizations
-
Vice-presidente
-
Nov 2016 - Oct 2018
- Creation of 20 positions out of 70 for interns specializing in "Pharmaceutical Innovation and Research". - Follow-up of the course of the interns specialized in IPR - Organization of the General Assembly of pharmacy interns in biology and hospital pharmacy (200 interns) - Creation of 20 positions out of 70 for interns specializing in "Pharmaceutical Innovation and Research". - Follow-up of the course of the interns specialized in IPR - Organization of the General Assembly of pharmacy interns in biology and hospital pharmacy (200 interns)
-
-
-
I-Stem
-
France
-
Research Services
-
1 - 100 Employee
-
Pharmacist Scientist in Translationnal Research
-
May 2017 - Oct 2017
- Affaires Réglementaires : aide à la rédaction de la brochure investigateur et du document CMC de l’IMPD pour le patch de cellules de l’épithélium pigmentaire rétinien dérivées de cellules souches embryonnaires dans le traitement de la Rétinite Pigmentaire (NCT03963154). - Unité de recherche : mise au point d’une méthode de différentiation des cellules souches embryonnaires en épithélium pigmentaire rétinien selon des conditions GMP - Affaires Réglementaires : aide à la rédaction de la brochure investigateur et du document CMC de l’IMPD pour le patch de cellules de l’épithélium pigmentaire rétinien dérivées de cellules souches embryonnaires dans le traitement de la Rétinite Pigmentaire (NCT03963154). - Unité de recherche : mise au point d’une méthode de différentiation des cellules souches embryonnaires en épithélium pigmentaire rétinien selon des conditions GMP
-
-
-
Greater Paris University Hospitals - AP-HP
-
France
-
Hospitals and Health Care
-
700 & Above Employee
-
-
Nov 2016 - Apr 2017
Gestion de la banque de sang de cordon
-
-
-
Jul 2016 - Oct 2016
Development of a stem cell encapsulation method for a ready-to-use injectable preparation after thawing
-
-
-
INSERM
-
France
-
Research Services
-
700 & Above Employee
-
Master's internship
-
Jan 2016 - Jun 2016
Development of a method using calcein AM to identify extracellular vesicles of cardiac progenitor cells derived from pluripotency-induced stem cells El Harane N, Kervadec A, Bellamy V, Pidial L, Neametalla HJ, Perier MC, Lima Correa B, Thiébault L, Cagnard N, Duché A, Brunaud C, Lemitre M, Gauthier J, Bourdillon AT, Renault MP, Hovhannisyan Y, Paiva S, Colas AR, Agbulut O, Hagège A, Silvestre JS, Menasché P, Renault NKE. Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors. Eur Heart J. 2018 May 21 Show less
-
-
-
Greater Paris University Hospitals - AP-HP
-
France
-
Hospitals and Health Care
-
700 & Above Employee
-
-
May 2015 - Oct 2015
Validation des dosages pharmacologiques et toxicologiques
-
-
-
Nov 2014 - Apr 2015
- Validation of pharmacological and toxicological assays- Therapeutic follow-up of patients treated with oral chemotherapies (tyrosine kinase inhibitors)- Development of an ELISA assay for plasma bevacizumab in patients with GliobastomaTabouret E, Rousseau B, Barrié M, Bequet C, Thiebault L, Chinot O and Hulin A. Bevacizumab Through Concentration in Recurrent Glioblastoma Patients. Journal of Integrative Oncology. 2015
-
-
-
PHARMACIE VOILLOT
-
France
-
Employé étudiant
-
Sep 2013 - Sep 2014
-
-
-
Hôpital Cochin
-
Paris
-
Extern
-
Oct 2011 - Sep 2012
Publication : D. Le Guiner, L. Thiebault, D. Talon, F. Chast. Moindre efficacité de détergence des produits inactivants totaux ? Pharmacien Hospitalier et Clinicien 12/2012 ; 47(4):269–270. Publication : D. Le Guiner, L. Thiebault, D. Talon, F. Chast. Moindre efficacité de détergence des produits inactivants totaux ? Pharmacien Hospitalier et Clinicien 12/2012 ; 47(4):269–270.
-
-
-
Pharmacie Villiers
-
Paris
-
Employé étudiant
-
Sep 2010 - Nov 2011
-
-
Education
-
Sorbonne Universités
Doctor of Philosophy - PhD, Ecole Doctorale Cognition, Comportement, Cerveau -
Université Paris Descartes
Diplôme d'Etudes Spécialisées, Innovation Pharmaceutique et Recherche -
Université de Paris
Doctor of Pharmacy - PharmD, Pharmacie clinique, hospitalière et de réseau de soins -
Université Paris Descartes
Diplôme Universitaire, Médicaments de Thérapie Innovante -
Université Paris Diderot
Diplôme inter-universitaire, Thérapie Cellulaire -
Université Paris-Est Créteil (UPEC)
Master 2 (M2), Biothérapie Tissulaire, Cellulaire et Génique