Experience

Fate Therapeutics Inc

• United States
• Biotechnology Research
• 200 - 300 Employee

• Principal Scientist

  • Jan 2022 - Present

  Develop bioanalytical assays for characterization and clinical lot release of iPSC-derived cellular immunotherapies including allogeneic CAR-T and CAR-NK cells. Qualify cellular and molecular methods in accordance with ICH guidelines and FDA expectations. Use cutting-edge technology including droplet digital PCR and multicolor flow cytometry. Maintain detailed records, use good documentation practices, analyze data and interpret results. Author and review standard operating procedures, reports, and IND sections. Lead teams developing analytical methods, manage analytical activities for drug programs, train personnel, and transfer technology. Manage multiple direct reports including research associates and scientists. Show less

• Senior Scientist

  • Jun 2020 - Dec 2021



Tocagen

• Research Scientist 2

  • Jan 2018 - Mar 2020

  Investigated drug efficacy and mechanisms of action at a clinical stage biotechnology and pharmaceutical company specializing in cancer gene therapies. Isolated, cryopreserved and cultured human PBMCs from clinical blood samples, then executed immunophenotyping and functional immune experiments using multicolor flow cytometry. Coordinated with contract research organizations to perform immunological measurements using multiplex digital ELISA and deconvolution of next generation sequencing of nucleic acids. Applied biostatistics to identify biomarkers related to patient outcomes in Phase 1 to 3 clinical trials. Maintained detailed records and author SOPs, work instructions, white papers, invention disclosures and patents, as well as assay development, qualification and experimental reports. Worked with and led cross-functional teams in a fast paced, high-pressure environment that required effective communication to internal and external audiences with varied backgrounds. Supported IND-enabling studies for novel cancer gene therapies. Managed multiple direct reports including interns and research associates. Show less

• Research Scientist 1

  • Mar 2016 - Jan 2019



DKFZ German Cancer Research Center

• Germany
• Research Services
• 700 & Above Employee

• Postdoctoral Research Scientist

  • Jul 2014 - Dec 2015

  Worked at the Institute for Cancer Prevention and Epidemiology and the Clinical Research Center at the University Hospital Freiburg in Germany. Performed epigenetic epidemiological studies of colon cancer and prostate cancer. Coordinated with clinicians, pathologists & biostatisticians. Helped organize longitudinal and cross-sectional population-based studies involving human participants. Worked at the Institute for Cancer Prevention and Epidemiology and the Clinical Research Center at the University Hospital Freiburg in Germany. Performed epigenetic epidemiological studies of colon cancer and prostate cancer. Coordinated with clinicians, pathologists & biostatisticians. Helped organize longitudinal and cross-sectional population-based studies involving human participants.



Harvard T.H. Chan School of Public Health

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Fellow

  • Jul 2013 - Jun 2014

  Worked at Brigham and Women's Hospital in the Department of OB/GYN Epidemiology. Developed next-generation sequencing library preparation methodologies, including RRBS, and applied them to human blood samples. Conducted DNA sequencing experiments on human blood and tissue samples from a birth cohort. Worked at Brigham and Women's Hospital in the Department of OB/GYN Epidemiology. Developed next-generation sequencing library preparation methodologies, including RRBS, and applied them to human blood samples. Conducted DNA sequencing experiments on human blood and tissue samples from a birth cohort.



Brown University

• United States
• Higher Education
• 700 & Above Employee

• Graduate Research Assistant

  • Sep 2008 - Jun 2013

  Worked in the Division of Biology and Medicine, Department of Pathology & Laboratory Medicine. Discovered epigenetic biomarkers of human cell subsets, created novel methods for human cell detection & quantification, designed & executed nucleic acid sequencing & microarray experiments, studied cancer epigenetics & immunology, graduate teaching assistant (The Biology of AIDS) & course grader (Pfizer Cancer Biology Course) Dissertation Title: Epigenetic Biomarkers for the Detection and Quantification of Human Leukocytes in Blood and Tissue Advisor: Kart T. Kelsey, M.D., M.O.H. Show less



Dartmouth College

• United States
• Higher Education
• 700 & Above Employee

• Research Assistant (Full Time)

  • Jun 2007 - Aug 2008

  Worked full time at Dartmouth Medical School, Department of Endocrine & MetabolismPerformed human and animal cell culture experiments, proteomic analysis, and biochemistryResearched AMP activated kinase signaling pathways in response to synthetic human hormonesPrincipal Investigator: Lee Witters, M.D.

• Undergraduate Teaching Assitant

  • Jan 2006 - May 2007

  Assisted in teaching laboratory courses in the Department of Biology, including Genetics, Cell Biology and Microbial Biology.