PHD Scholar

• Sep 2021 - Present

- Presented poster at SRBCE international conference 2022. - Wrote a comprehensive review on ‘infertility management strategies’. Paper under peer review. - Presented poster at SRBCE international conference 2022. - Wrote a comprehensive review on ‘infertility management strategies’. Paper under peer review.

Clinical genetics trainer

• Dec 2020 - Present

Connecting the concepts of Human Genetics to clinical genetics for lab professionals from 3 different countries. Connecting the concepts of Human Genetics to clinical genetics for lab professionals from 3 different countries.

Genetics Consultant

• Mar 2022 - Aug 2023

Research Fellow

• May 2021 - Sep 2021

~Handled cytogenetic harvesting, analysis and reporting of postnatal and infertility blood samples. ~Supported the clinical microarray testing of prenatal and postnatal samples on CytoScan 350K array. ~Processed, analysed and reported cytogenetic male infertility research samples when in-house. ~Wrote a case series paper on diagnosis of Cornelia de Lange syndrome using the data available in the lab. Employers repositioned my authorship from first to last and/or never pursued towards… Show more ~Handled cytogenetic harvesting, analysis and reporting of postnatal and infertility blood samples. ~Supported the clinical microarray testing of prenatal and postnatal samples on CytoScan 350K array. ~Processed, analysed and reported cytogenetic male infertility research samples when in-house. ~Wrote a case series paper on diagnosis of Cornelia de Lange syndrome using the data available in the lab. Employers repositioned my authorship from first to last and/or never pursued towards publication. Remains a mystery! Show less ~Handled cytogenetic harvesting, analysis and reporting of postnatal and infertility blood samples. ~Supported the clinical microarray testing of prenatal and postnatal samples on CytoScan 350K array. ~Processed, analysed and reported cytogenetic male infertility research samples when in-house. ~Wrote a case series paper on diagnosis of Cornelia de Lange syndrome using the data available in the lab. Employers repositioned my authorship from first to last and/or never pursued towards… Show more ~Handled cytogenetic harvesting, analysis and reporting of postnatal and infertility blood samples. ~Supported the clinical microarray testing of prenatal and postnatal samples on CytoScan 350K array. ~Processed, analysed and reported cytogenetic male infertility research samples when in-house. ~Wrote a case series paper on diagnosis of Cornelia de Lange syndrome using the data available in the lab. Employers repositioned my authorship from first to last and/or never pursued towards publication. Remains a mystery! Show less

Bioinformatic Research consultant

• Jun 2020 - Jan 2021

Designed bioinformatic pipeline for four phases for nutrigenomic diet recommendations. Discovered risk scoring method for small set of samples for metabolic traits. Designed bioinformatic pipeline for four phases for nutrigenomic diet recommendations. Discovered risk scoring method for small set of samples for metabolic traits.

Guest Speaker

• Dec 2020 - Dec 2020

Skill training on "Molecular cytogenomics and its role in Genetic diagnosis and counseling" Skill training on "Molecular cytogenomics and its role in Genetic diagnosis and counseling"

Genome Application Technologist

• Nov 2018 - May 2019

1. Genetic test development ranging from cytogenetic tests to SNP Microarrays and PCR-based tests. 2. Assistance for analysis, comparison and reporting of clinically important findings from microarray raw results pertaining to prenatal, postnatal and cancer diagnosis. 3. Overall cytogenetic lab development for obtaining CAP/CLIA accreditation. 4. Training and protocol development for conducting clinical genetic tests - karyotyping, FISH, PCR, SNP Microarray. 1. Genetic test development ranging from cytogenetic tests to SNP Microarrays and PCR-based tests. 2. Assistance for analysis, comparison and reporting of clinically important findings from microarray raw results pertaining to prenatal, postnatal and cancer diagnosis. 3. Overall cytogenetic lab development for obtaining CAP/CLIA accreditation. 4. Training and protocol development for conducting clinical genetic tests - karyotyping, FISH, PCR, SNP Microarray.

Guest Speaker

• Aug 2018 - Aug 2018

Topic - Recent Advances in Molecular Diagnostics Topic - Recent Advances in Molecular Diagnostics

Microarray section supervisor

• Nov 2016 - May 2018

• Developed new standard operating procedures and quality control/preventive maintenance protocols for cancer microarray testing, ensuring new testing regulatory compliance and certification requirements. Also, coordinated collaborative academic research cases with Childrens’ Oncology Group (COG). Wrote a paper on validation of oncoarrays but due to retraction/absence of patient consent, couldnot process to publication. • Was the Team Leader for the microarray team ensuring microarray… Show more • Developed new standard operating procedures and quality control/preventive maintenance protocols for cancer microarray testing, ensuring new testing regulatory compliance and certification requirements. Also, coordinated collaborative academic research cases with Childrens’ Oncology Group (COG). Wrote a paper on validation of oncoarrays but due to retraction/absence of patient consent, couldnot process to publication. • Was the Team Leader for the microarray team ensuring microarray testing quality, safety, timeliness and regulatory compliance; developed team member & conducted team competencies and performance evaluations relevant College of American Pathologists (CAP) proficiency testing. • Determined best testing options through test preview, consultation with Client Services, Genetic Counselors, Directors, and Clinicians; coordinated processing and analysis priorities; and review/interpret microarray/cytogenetics test results for Director’s review and release of results, every week. • Processed and analyzed clinical microarray samples, as needed • Developed and implemented laboratory improvement workflows in order to optimize value-to-patient testing, an example is creating communication workflow between prenatal culture team, chromosome analysis team and microarray team handling same sample for prenatal CMA and cytogenetic testing, thus, reducing patient reporting delays/errors. • Participated in continuing education, orientation, training and maintained professional certification by incorporating CMA (Chromosomal Microarray) School. Establishment of CMA school involved development of curriculum with 10 classes covering molecular genetics/genomics, bioinformatics and bioengineering topics. Delegated as well as taught theoretical and practical application of clinical microarray technique for the fellow cytogenetic professionals in the laboratory. Show less • Developed new standard operating procedures and quality control/preventive maintenance protocols for cancer microarray testing, ensuring new testing regulatory compliance and certification requirements. Also, coordinated collaborative academic research cases with Childrens’ Oncology Group (COG). Wrote a paper on validation of oncoarrays but due to retraction/absence of patient consent, couldnot process to publication. • Was the Team Leader for the microarray team ensuring microarray… Show more • Developed new standard operating procedures and quality control/preventive maintenance protocols for cancer microarray testing, ensuring new testing regulatory compliance and certification requirements. Also, coordinated collaborative academic research cases with Childrens’ Oncology Group (COG). Wrote a paper on validation of oncoarrays but due to retraction/absence of patient consent, couldnot process to publication. • Was the Team Leader for the microarray team ensuring microarray testing quality, safety, timeliness and regulatory compliance; developed team member & conducted team competencies and performance evaluations relevant College of American Pathologists (CAP) proficiency testing. • Determined best testing options through test preview, consultation with Client Services, Genetic Counselors, Directors, and Clinicians; coordinated processing and analysis priorities; and review/interpret microarray/cytogenetics test results for Director’s review and release of results, every week. • Processed and analyzed clinical microarray samples, as needed • Developed and implemented laboratory improvement workflows in order to optimize value-to-patient testing, an example is creating communication workflow between prenatal culture team, chromosome analysis team and microarray team handling same sample for prenatal CMA and cytogenetic testing, thus, reducing patient reporting delays/errors. • Participated in continuing education, orientation, training and maintained professional certification by incorporating CMA (Chromosomal Microarray) School. Establishment of CMA school involved development of curriculum with 10 classes covering molecular genetics/genomics, bioinformatics and bioengineering topics. Delegated as well as taught theoretical and practical application of clinical microarray technique for the fellow cytogenetic professionals in the laboratory. Show less

Clinical Application Research Student

• Jun 2015 - Jul 2016

• Created workflow for clinical data analysis of data obtained from Affymetrix CytoScan SNP microarray for childhood sarcoma cases using Chromosome Analysis Suite and Nexus Copy Number softwares. • Identified copy number alterations involved in various types of sarcomas for 22 patients and validated the SNP array data with whole exome data. • Conducted Primer Design and Sanger Sequencing for validating fusion transcripts in solid tumor samples, and tumor DNA isolation. • Created workflow for clinical data analysis of data obtained from Affymetrix CytoScan SNP microarray for childhood sarcoma cases using Chromosome Analysis Suite and Nexus Copy Number softwares. • Identified copy number alterations involved in various types of sarcomas for 22 patients and validated the SNP array data with whole exome data. • Conducted Primer Design and Sanger Sequencing for validating fusion transcripts in solid tumor samples, and tumor DNA isolation.

Group Student Project Lead

• Dec 2014 - May 2015

• Created and Validated Home-Brew FISH Probes for novel HNRNPK gene in 50 AML patients. • Validated HANABI PIV Automated Metaphase Spreader for dropping using 95 slides from 19 samples for the Clinical Cytogenetics Laboratory at MD Anderson Cancer Center.

Clinical Rotation student

• Apr 2015 - Apr 2015

• Learned the handling, culturing, mapping, karyotyping and reporting of real cancer cases. • Observed the various types of FISH probes used and their analysis.

Clinical Rotation student

• Feb 2015 - Feb 2015

• Learned the handling, culturing, mapping, karyotyping and reporting of real prenatal samples. • Conducted validation for FISH probes 7q, 20q, CBFB and MLL break apart probes. • Learned the handling, culturing, mapping, karyotyping and reporting of real prenatal samples. • Conducted validation for FISH probes 7q, 20q, CBFB and MLL break apart probes.

Research Fellow

• Jan 2013 - Aug 2013

• Worked on epigenetic study of genes associated with childhood obesity. • Designed and implemented the protocol that analyzed the methylation profiling of genes (ADIPOQ, TNF-alpha, RETN, LEP & LEPR) using bisulphite sequencing. • Performed genotyping of 2500 samples of North Indian population to obtain the pharmacogenetic map of clopidogrel effect. Till date remain a ghost author. • Experienced in conducting and managing blood camps. • Proposed and performed the Insilico… Show more • Worked on epigenetic study of genes associated with childhood obesity. • Designed and implemented the protocol that analyzed the methylation profiling of genes (ADIPOQ, TNF-alpha, RETN, LEP & LEPR) using bisulphite sequencing. • Performed genotyping of 2500 samples of North Indian population to obtain the pharmacogenetic map of clopidogrel effect. Till date remain a ghost author. • Experienced in conducting and managing blood camps. • Proposed and performed the Insilico experimentation for finding selection signatures in North Indian population. Paper thrown away by PI because of my intention for marriage. • Expertise in using bioinformatics tools ranging from Terminal to HaploPS involving in extraction of protein, gene and SNP databases. Show less • Worked on epigenetic study of genes associated with childhood obesity. • Designed and implemented the protocol that analyzed the methylation profiling of genes (ADIPOQ, TNF-alpha, RETN, LEP & LEPR) using bisulphite sequencing. • Performed genotyping of 2500 samples of North Indian population to obtain the pharmacogenetic map of clopidogrel effect. Till date remain a ghost author. • Experienced in conducting and managing blood camps. • Proposed and performed the Insilico… Show more • Worked on epigenetic study of genes associated with childhood obesity. • Designed and implemented the protocol that analyzed the methylation profiling of genes (ADIPOQ, TNF-alpha, RETN, LEP & LEPR) using bisulphite sequencing. • Performed genotyping of 2500 samples of North Indian population to obtain the pharmacogenetic map of clopidogrel effect. Till date remain a ghost author. • Experienced in conducting and managing blood camps. • Proposed and performed the Insilico experimentation for finding selection signatures in North Indian population. Paper thrown away by PI because of my intention for marriage. • Expertise in using bioinformatics tools ranging from Terminal to HaploPS involving in extraction of protein, gene and SNP databases. Show less

Student Research Fellow

• Dec 2011 - May 2012

• Worked on research project titled: "Characterization and Molecular Detection of Streptococcus pneumoniae from body fluids of children aged between 0-5yrs" • Conducted Antibiotic Susceptibility Testing and serotyping on E. coli and S. pneumoniae isolates using different dosages of penicillin and erythromycin antibiotics to evaluate antibiotic resistance. • Worked on research project titled: "Characterization and Molecular Detection of Streptococcus pneumoniae from body fluids of children aged between 0-5yrs" • Conducted Antibiotic Susceptibility Testing and serotyping on E. coli and S. pneumoniae isolates using different dosages of penicillin and erythromycin antibiotics to evaluate antibiotic resistance.

Student Intern

• May 2011 - Jun 2011

• Conducted DNA isolation from blood samples of pregnant women, allele-specific PCR and gel electrophoresis for identifying SNP in MTHFR and TNFα genes. • Conducted DNA isolation from blood samples of pregnant women, allele-specific PCR and gel electrophoresis for identifying SNP in MTHFR and TNFα genes.

Observer

• May 2008 - May 2008

• DNA isolation and gel electrophoresis from pediatric blood samples using manual salting out method. • DNA isolation and gel electrophoresis from pediatric blood samples using manual salting out method.