Maurizio Varrone

Principal Investigator at Axxam S.p.A
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Contact Information
us****@****om
(386) 825-5501
Location
Italy, IT
Languages
  • Italian Native or bilingual proficiency
  • English Full professional proficiency

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Experience

    • Italy
    • Biotechnology Research
    • 100 - 200 Employee
    • Principal Investigator
      • May 2018 - Present

    • Singapore
    • Research Services
    • 1 - 100 Employee
    • Program Director SPARK AT NTU
      • Jun 2015 - Jun 2017

      SPARK AT NTU is a translational research program aimed at supporting researchers of the Nanyang Technological University of Singapore in the development of academic research in new therapies, products and tools. The translational activities are coupled with educational activities aimed at increasing faculty and staff members’ knowledge of the principals and practises of the pharmaceutical and biomedical industry. The program has been created based upon SPARK AT STANFORD, a platform created by Stanford University School of medicine in 2007. The program is integrated in NTUitive the innovation and enterprise company of Nanyang Technological University which manages the University’s intellectual property and handles the challenges of commercialisation of early stage technologies. Show less

    • United Kingdom
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Investigator
      • Sep 2013 - Jun 2015

      Responsible for the activities aimed at the identification of lead molecules for the treatment of neurodegenerative diseases applying phenotypic screen approaches. The main responsibilities include: definition, prioritization and implementation of the activities to follow up the results of the HTS campaigns; data analysis to define compound series and to identify their strengths and potential liabilities; coordination of the activities performed by scientist in different units/sites. Responsible for the activities aimed at the identification of lead molecules for the treatment of neurodegenerative diseases applying phenotypic screen approaches. The main responsibilities include: definition, prioritization and implementation of the activities to follow up the results of the HTS campaigns; data analysis to define compound series and to identify their strengths and potential liabilities; coordination of the activities performed by scientist in different units/sites.

    • Group Leader (Medicinal Chemistry)
      • Oct 2008 - Sep 2013

      Responsible for scientific activities and for the management of a group of up to 9 graduated chemists and technicians. The main responsibilities include: quality/quantity of the synthetic chemistry performed within the group, Lab safety, performing annual employee’s appraisal and definition of personal development plans, close monitoring and definition of OPEX/CAPEX, selection of new candidates, mentoring and traing of junior staff.

    • Project leader
      • Jun 2006 - Sep 2013

      Initially co-project leader of a neurooncology project based on a pathway screen approach with the responsibility of running the project starting from the assay development phase to hit series identification. Still maintaining the same involvement in the project I have taken full responsibility of a target based project in the screen to hit phase always in the neurooncology area. Both roles include as main activities the coordination of a multidisciplinary team, the definition and implementation of project strategy and plans, reporting to the strategy and portfolio comities. Show less

    • Senior Scientist (Medicinal Chemistry)
      • Jul 2004 - Mar 2009

      Worked on hit-to-lead and lead optimization phases of an internal project in the neuroprotection area. Responsible for design, synthesis and characterization of new chemical entities and responsible for the coordination of chemists working on the project. Team member reporting to project meetings and to external collaborators. Main reference point for the scientific/organisational coordination of CRO.

    • Germany
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Senior Scientist
      • Jul 2002 - Jul 2004

      Worked on hit-to-lead and lead optimization customer research programs. Main activities: validation of new synthetic routes, design and synthesis of single compounds and focused libraries (20-250 compounds), quality control before dispatch of compounds to customers, reporting of project progress internally and to customers in telephone conferences. Worked on hit-to-lead and lead optimization customer research programs. Main activities: validation of new synthetic routes, design and synthesis of single compounds and focused libraries (20-250 compounds), quality control before dispatch of compounds to customers, reporting of project progress internally and to customers in telephone conferences.

    • Italy
    • Research Services
    • 700 & Above Employee
    • Scientist
      • Oct 1997 - Mar 1999

      Involved in different projects in the area of protein purification and immobilization and responsible for the renewal of the laboratory facilities. Main project: Synthesis and characterisation of new poly(vinyl alcohol) based matrix for the immobilisation of lipolytic enzymes. Involved in different projects in the area of protein purification and immobilization and responsible for the renewal of the laboratory facilities. Main project: Synthesis and characterisation of new poly(vinyl alcohol) based matrix for the immobilisation of lipolytic enzymes.

Education

  • University of Bath
    PhD; Degree, Chemistry; Organic Chemistry
    1999 - 2002
  • Sapienza Università di Roma
    Master's Degree, Organic Chemistry
    1989 - 1995

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