Vic Keschrumrus, Ph.D.
Postdoctoral Research Associate at University of Arizona- Claim this Profile
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Bio
Credentials
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Lean Six Sigma White Belt Certification
US Navy
Experience
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University of Arizona
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Research Associate
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Aug 2021 - Present
Department of Cellular and Molecular Medicine (College of Medicine)▪ Established Engineering Heart Tissue platform for drug screening and disease modeling at the College of Medicine Phenotyping Core Facility.▪ Rapid prototyping tissue culture devices with SolidWorks and 3D printing.▪ Developed experiments from the titin protein level up to the whole engineered tissue.▪ Trained employees and students on research techniques and equipment to maintain an efficient working environment.▪ Member of a multi-disciplinary team consisting of engineers, biologists, physicists, and students.
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Graduate Research Associate
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Aug 2014 - Aug 2021
Department of Biomedical Engineering (College of Engineering)▪ Designed and constructed the first Engineering Heart Tissue platform in North America for titin-based disease modeling and therapeutic testing.▪ Discovered the influence of extracellular matrix on engineered heart tissue development and titin maturity (publication pending).▪ Designed and tested antisense oligonucleotide (AON) for exon skipping mutations (gene therapy).▪ Performed stem cell cardiomyocyte differentiation and cardiomyocyte isolation from neonatal rodent hearts.▪ Analyzed sarcomeric ultrastructure (EM) and proteins (titin and MHC).▪ Presented scientific findings (posters, abstracts, and oral presentations) internally and at regional/international conferences.
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Children's Hospital of Orange County
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Orange County, California, United States
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Research Associate II
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Apr 2008 - Jan 2011
CHOC Research Institute: Center for Neuroscience and Stem Cell Research (Neuro-Oncology) ▪ Studied the influence of the extracellular matrix on tumor and stem cell function using polymer chemistry, tensile testing, plasmid DNA transfection, protein purification, gel electrophoresis, PCR, ICC, IHC, zymography, western blot, immunofluorescence, and time-lapse microscopy. ▪ Fabricated microfluidic devices (photolithography and soft lithography) to study patterned proteins and chemotaxis. ▪ Established novel primary cell lines extracted from patient tumor samples. ▪ Repaired and maintained sensitive laboratory equipment.
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University of California - Irvine
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Irvine, CA
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Graduate Researcher and Teaching Assistant
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Jun 2005 - Jul 2007
Department of Biomedical Engineering - Samueli School of Engineering • Utilized a variety of techniques from bioengineering and cellular and molecular biology, including cell culture (melanoma cells, human aortic smooth muscle cells, mouse myocytes, and e-Coli), scaffold construction via polymer chemistry, transfection of plasmid DNA, protein purification and gel electrophoresis, immunofluorescence staining, and time-lapse microscopy PUBLICATION: Peyton SR, Raub CB, Keschrumrus VP, and Putnam AJ. (2006) “The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells.” Biomaterials. Oct;27(28):4881-93
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Monarch Labs
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Irvine, CA
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Quality Assurance and Materials Manager
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Jan 2007 - Jun 2007
• Developed and enforced a new QA system to improve the efficiency of materials record-keeping and tracking • Duties also expanded to include tasks in the insectary, culture testing and R&D in the microbiology laboratory, safety and quality control in the shipping department, and IT/Networking improvement projects for the company • Monitored and tested all incoming, circulating, and manufactured materials in accordance with established SOPs and GMPs • Developed and enforced a new QA system to improve the efficiency of materials record-keeping and tracking • Duties also expanded to include tasks in the insectary, culture testing and R&D in the microbiology laboratory, safety and quality control in the shipping department, and IT/Networking improvement projects for the company • Monitored and tested all incoming, circulating, and manufactured materials in accordance with established SOPs and GMPs
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Research Assistant
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Apr 2003 - Jun 2005
• Investigated melanoma development and progression on polystyrene, polyacrylamide, and Matrigel via migration assays • Formulated method to couple DNA to extracellular matrix for enhanced gene transfection • Investigated melanoma development and progression on polystyrene, polyacrylamide, and Matrigel via migration assays • Formulated method to couple DNA to extracellular matrix for enhanced gene transfection
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Education
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2014 - 2021
University of Arizona
Doctor of Philosophy (Ph.D.), Biomedical Engineering -
2005 - 2007
University of California, Irvine
Master of Science, Biomedical Engineering -
2001 - 2005
University of California, Irvine
Bachelor of Science (B.S.), Biomedical Engineering
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