Jonathan H Chan

President at Oxford University Biotech Society
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Contact Information
us****@****om
(386) 825-5501
Location
Greater Oxford Area, UK

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Bio

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Credentials

  • freeCodeCamp Scientific Computing with Python Developer Certification
    freeCodeCamp
    Aug, 2020
    - Oct, 2024

Experience

  • Oxford University Biotech Society
    • United Kingdom
    • Biotechnology Research
    • 1 - 100 Employee
    • President
      • Jun 2023 - Present

      Leading the Oxford University Biotech Society with fellow President Daniel Kochin to inspire and engage the Oxford student community. Leading the Oxford University Biotech Society with fellow President Daniel Kochin to inspire and engage the Oxford student community.

  • University of Oxford
    • United Kingdom
    • Research Services
    • 700 & Above Employee
    • Doctoral Student
      • Oct 2022 - Present

      Under the supervision of Prof. Hugh Watkins and Prof. Anuj Goel, I am personalising risk prediction for hypertrophic cardiomyopathy, the most common genetic heart disease. Specifically, I am applying bioinformatic and ML/DL tools to build predictive models such as genetic risk scores in R and Python. Under the supervision of Prof. Hugh Watkins and Prof. Anuj Goel, I am personalising risk prediction for hypertrophic cardiomyopathy, the most common genetic heart disease. Specifically, I am applying bioinformatic and ML/DL tools to build predictive models such as genetic risk scores in R and Python.

  • University of Oxford
    • United Kingdom
    • Research Services
    • 700 & Above Employee
    • Masters Student
      • Sep 2021 - Jun 2022

      Under the supervision of Prof. Yang Shi at the University of Oxford Ludwig Institute for Cancer Research, I discovered several potential vulnerabilities in the childhood brain cancer, diffuse intrinsic pontine glioma (DIPG). Specifically, I applied genome-wide CRISPR-knockout screening to isogenic DIPG cell lines to identify synthetic lethalities in DIPG. This was recognised by the University of Oxford Department of Biochemistry with a Departmental Project Prize. Under the supervision of Prof. Yang Shi at the University of Oxford Ludwig Institute for Cancer Research, I discovered several potential vulnerabilities in the childhood brain cancer, diffuse intrinsic pontine glioma (DIPG). Specifically, I applied genome-wide CRISPR-knockout screening to isogenic DIPG cell lines to identify synthetic lethalities in DIPG. This was recognised by the University of Oxford Department of Biochemistry with a Departmental Project Prize.

  • EPFL (École polytechnique fédérale de Lausanne)
    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Summer Research Student
      • Jul 2021 - Aug 2021

      Under the supervision of Prof. Jacques Fellay, I conducted research into the application of machine learning & statistical approaches to uncover what drives accelerated aging in HIV-infected individuals. Specifically, I investigated potential epidemiological drivers of somatic mutagenesis in nuclear DNA using patient exomes via R. Under the supervision of Prof. Jacques Fellay, I conducted research into the application of machine learning & statistical approaches to uncover what drives accelerated aging in HIV-infected individuals. Specifically, I investigated potential epidemiological drivers of somatic mutagenesis in nuclear DNA using patient exomes via R.

  • University of Oxford iGEM
    • United Kingdom
    • Biotechnology Research
    • Scientific Researcher
      • Jan 2019 - Nov 2019

      Under the supervision of Prof. Mark Howarth of the University of Oxford Department of Biochemistry, I conducted research towards the ab initio development of a novel therapeutic for C. difficile infection as part of the Oxford iGEM Team of 2019. Conventional molecular biology techniques as PCR; SDS-PAGE; Western blotting etc. were used in addition to Gibson assembly for genetic engineering of Escherichia coli and Lactobacillus reuteri. Additional contributions beyond the wet lab included: - Modelling Consultant via adapting MATLAB computational models to our probiotic system - Website Coding Lead via HTML/CSS Notably, the project garnered a Gold Medal at the iGEM Jamboree 2019 in addition to a nomination for the best undergraduate therapeutics project (top 5 projects). Show less

  • The University of Auckland
    • New Zealand
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • Jul 2018 - Oct 2018

      Under the supervision of Prof. Jane Allison of the University of Auckland School of Biological Sciences, I conducted full-time research into the interactions of synthetic antimicrobial peptides with model bacterial membranes in silico. Specifically, computational modelling of biological systems was achieved via molecular dynamics simulations (GROMACS), with results published in Chakraborty et al. (2021). In conjunction with the internship, I attended the following two scientific conferences in Dec 2018: - AsCA/CRYSTAL 32 in Auckland, New Zealand (Asian Crystallographic Association & Society of Crystallographers in Australia and New Zealand) - QUACCS (Quantum and Computational Chemistry Student Conference) 3.0 in Kioloa, Australia (Australian National University & Australian Association of Theoretical and Computational Chemists) Show less

Education

  • University of Oxford
    DPhil in Medical Sciences
    2022 -
  • University of Oxford
    Master of Biochemistry
    2018 - 2022
  • Auckland Grammar School
    High School
    2013 - 2017

Community

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