Experience

Vibliome Therapeutics, LLC

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• • Feb 2023 - Present

  At Vibliome, I lead efforts in target selection, discovery biology, DMPK, in vivo pharmacology, and preclinical safety.

• • Jun 2019 - Feb 2023



SPARK Drug Discovery

• Stanford University, School of Medicine

• Project Leader

  • Jan 2013 - Jun 2019



Stanford University School of Medicine

• United States
• Higher Education
• 700 & Above Employee

• Male Contraceptive Initiative Fellow

  • Jul 2018 - May 2019

  Demonstrated that homeodomain-interacting protein kinase 4 (HIPK4) is essential for spermiogenesis and male fertility in mice using knockout mouse models and cultured cells. I found that HIPK4 regulates F-actin dynamics in key structures that shape the sperm head as it transforms from a round to elongated spermatid. male fertility, sperm assessment, electron microscopy, histology, immunofluorescence, phosphoproteomics, microarray analysis, drug development Demonstrated that homeodomain-interacting protein kinase 4 (HIPK4) is essential for spermiogenesis and male fertility in mice using knockout mouse models and cultured cells. I found that HIPK4 regulates F-actin dynamics in key structures that shape the sperm head as it transforms from a round to elongated spermatid. male fertility, sperm assessment, electron microscopy, histology, immunofluorescence, phosphoproteomics, microarray analysis, drug development



Stanford University School of Medicine

• United States
• Higher Education
• 700 & Above Employee

• American Cancer Society Postdoctoral Fellow

  • Jul 2013 - Jul 2016

  As a postdoctoral fellow at Stanford University, I used chemical genetics, quantitative proteomics, and standard techniques in molecular/cellular/chemical biology and biochemistry to study kinase signaling and activation of the Hedgehog pathway. I also validated a set of proprietary, small molecule kinase inhibitors developed in collaboration with Spacefill Enterprises, LLC, and explored the links between our kinase of interest and a variety of cancers in cultured cell lines. As a postdoctoral fellow at Stanford University, I used chemical genetics, quantitative proteomics, and standard techniques in molecular/cellular/chemical biology and biochemistry to study kinase signaling and activation of the Hedgehog pathway. I also validated a set of proprietary, small molecule kinase inhibitors developed in collaboration with Spacefill Enterprises, LLC, and explored the links between our kinase of interest and a variety of cancers in cultured cell lines.



University of Wisconsin-Madison

• Higher Education
• 700 & Above Employee

• Graduate Student

  • Aug 2007 - Jul 2012

  As a graduate student at UW-Madison, I trained in the laboratory of Professor Helen Blackwell. My research was focused on the design, synthesis, and structural characterization of a class of peptidomimetics called peptoids. I discovered two new peptoid secondary structures (extended sheet and ribbon), and helped characterize two other new secondary structures, using NMR, X-ray crystallization, circular dichroism, and IR spectroscopy. As a graduate student at UW-Madison, I trained in the laboratory of Professor Helen Blackwell. My research was focused on the design, synthesis, and structural characterization of a class of peptidomimetics called peptoids. I discovered two new peptoid secondary structures (extended sheet and ribbon), and helped characterize two other new secondary structures, using NMR, X-ray crystallization, circular dichroism, and IR spectroscopy.



MedImmune

• United States
• Biotechnology Research
• 700 & Above Employee

• Research Assistant, Biochemical Engineer

  • 2006 - 2007

  • Analyzed liquid chromatography purification of antibody therapeutics during a scale-up process. • Validated the viral clearance and column lifetimes at each step of the purification. • Analyzed liquid chromatography purification of antibody therapeutics during a scale-up process. • Validated the viral clearance and column lifetimes at each step of the purification.